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Prevalence of Psychotic Disorders in Patients with Obsessive-Compulsive Disorder

Published online by Cambridge University Press:  07 November 2014

Lieuwe de Haan ,
Christine Dudek-Hodge ,
Yolanda Verhoeven  and
Damiaan Denys
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Abstract

Introduction: The co-occurrence of obsessive-compulsive disorder (OCD) in patients with schizophrenia and related disorders has been increasingly recognized. However, the rate of psychosis comorbidity in OCD patients has yet to be systematically evaluated.

Methods: The prevalence of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition psychotic disorders was evaluated in 757 subjects consecutively referred to a specialised diagnostic and treatment facility for OCD. Demographic and clinical characteristics were assessed.

Results: Thirteen OCD patients (1.7%) also met the DSM-IV criteria for a psychotic disorder. We found no significant differences in clinical characteristic between OCD patients with and without a psychotic disorder, although patients with OCD and a psychotic disorder more likely used illicit substances and more likely were male.

Conclusion: Relatively few patients referred to a specialized treatment OCD center suffer from a psychotic disorder.

Type
Original Research
Information
CNS Spectrums , Volume 14 , Issue 8 , August 2009 , pp. 415 - 418
Copyright
Copyright © Cambridge University Press 2009

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References

REFERENCES

1.Eisen, JL, Beer, DA, Pato, MT, Venditto, TA, Rasmussen, SA. Obsessive-compulsive disorder in patients with schizophrenia or schizoaffective disorder. Am J Psychiatry. 1997;154:271–273.Google Scholar
2.Porto, L, Bermanzohn, P, Pollack, S, et al.A profile of obsessive compulsive symptoms in schizophrenia. CNS Spectr. 1997;2:21–25.Google Scholar
3.Fabisch, K, Fabisch, H, Langs, G, Huber, HP, Zapotoczky, HG. Incidence of obsessive-compulsive phenomena in the course of acute schizophrenia and schizoaffective disorder. Eur Psychiatry. 2001;16:336–341.CrossRefGoogle ScholarPubMed
4.Poyurovsky, M, Fuchs, C, Weizman, A. Obsessive-compulsive disorder in patients with first episode schizophrenia. Am J Psychiatry. 1999;156:1998–2000.Google Scholar
5.Poyurovsky, M, Hramenkov, S, Isakov, V, e al. Obsessive-compulsive disorder in hospitalized patients with chronic schizophrenia. Psychiatry Res. 2001;102:49–57.Google Scholar
6.Tibbo, P, Kroetsch, M, Chue, P, Warneke, L. Obsessive-compulsive disorder in schizophrenia. J Psychiatr Res. 2000;34:139–146.Google Scholar
7.Sevincok, L, Akoglu, A, Arslantas, H: Schizo-obsessive and obsessive compulsive disorder: Comparison of clinical characteristics and neurological soft signs. Psychiatry Res. 2006;145:241–248.CrossRefGoogle ScholarPubMed
8.Rajkumar, R, Reddy, J, Kandavel, T. Clinical profile of schizo-obsessive disorder: a comparative study. Compr Psychiatry. 2008;49:262–268.Google Scholar
9.Poyurovsky, M, Kriss, V, Weismann, G, et al.Comparison of clinical characteristics and comorbidity in schizophrenia patients with and without obsessive compulsive disorder: schizophrenic and OC symptoms in schizophrenia. J Clin Psychiatry. 2003;64:1300–1307.Google Scholar
10.Poyurovsky, M, Faragian, S, Pashinian, Aet al.Clinical characteristics of schizotypical related obsessive–compulsive disorder. Psychiatry Res. 2008;159:254–258.Google Scholar
11.Ganesan, V, Kumar, TC, Khanna, S. Obsessive-compulsive disorder and psychosis. Can J Psychiatry. 2001;46:750–754.Google Scholar
12.Kamo, M, Golding, JM, Sorenson, SB, Burnam, MA. The epidemiology of obsessive-compulsive disorder in five US communities. Arch Gen Psychiatry. 1988;45:1094–1099.Google Scholar
13.Fenton, WS, McGlashan, TH. The prognostic significance of obsessive-compulsive symptoms in schizophrenia. Am J Psychiatry. 1986;143:437–441.Google ScholarPubMed
14.Goodman, WK, Price, LH, Rasmussen, SA, et al.The Yale-Brown Obsessive Compulsive Scale, II: validity. Arch Gen Psychiatry. 1989;46:1012–1016.Google Scholar
15.de Haan, L, Hoogenboom, B, Beuk, N, Wouters, L, Dingemans, PM, Linszen, DH. Reliability and validity of the Yale-Brown Obsessive-Compulsive Scale in schizophrenia patients. Psychopharmacol Bull. 2006;39:25–30.Google Scholar
16.de Haan, L, Linszen, DH, Gorsira, R. Clozapine and obsessions in patients with recent onset schizophrenia and other psychotic disorders. J Clin Psychiatry. 1999;60:364–365.CrossRefGoogle ScholarPubMed
17.Van Nimwegen, L, De Haan, L, van Beveren, N, et al.Obsessive-Compulsive Symptoms in a Randomized, Double-Blind Study With Olanzapine or Risperidone in Young Patients With Early Psychosis. J Clin Psychopharmacol. 2008;28:214–218.Google Scholar
18.De Haan, L, Oekeneva, A, Van Amelsvoort, T, Linszen, D. Obsessive-Compulsive Disorder and treatment with clozapine in 200 patients with recent-onset schizophrenia or related disorders. Eur Psychiatry. 2004;19:524.Google Scholar
19.De Haan, L, Beuk, N, Hoogenboom, B, Dingemans, P, Linszen, D. Obsessive-Compulsive Symptoms during treatment with olanzapine and risperidone, a prospective study of 113 patients with recent-onset schizophrenia or related disorders. J Clin Psychiatry. 2002;63:104–107.CrossRefGoogle ScholarPubMed
20.Reddy, Y, Reddy, RSrinath, S, Khanna, S, Sheshadri, SP, Girimaji, SC. Comorbidity in juvenile obsessive-compulsive disorder: A report from India. Can J Psychiatry. 2000;45:274–278.Google Scholar
21.Pigott, T, L'Heureux, F, Dubbert, B, Berstein, S, Murphy, DL. Obsessive compulsive disorder: comorbid conditions. J Clin Psychiatry. 1994;55(suppl):15–27.Google ScholarPubMed
22.Poyurovsky, M, Fuchs, C, Faragian, S. Prefential aggregation of obsessive-compulsive spectrum disorders in schizophrenia patients with obsessive-compulsive disorder. Can J Psychiatry. 2006;51:746–754.Google Scholar
23.Whitney, K, Fastenau, P, Evans, J, Lysaker, PH. Comparative neuropsychological function in obsessive-compulsive disorder and schizophrenia with and without obsessive-compulsive symptoms. Schizophr Res. 2004;69:75–83.Google Scholar