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Perspectives on Current Directions in the Neurobiology of Addiction Disorders Relevant to Genetic Risk Factors

Published online by Cambridge University Press:  07 November 2014

Yasmin L. Hurd
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Abstract

There is a significant heritability of drug addiction disorders, but potential genes that may underlie such vulnerability have not been clearly identified. Common neurobiological candidates for drug abuse include genes related to dopamine, opioid neuropeptide, and glutamate transmission that play important roles in drug reward and inhibitory control. This article provides an overview of genetic polymorphisms linked to these neurobiological systems, particularly in relation to psychostimulant- and opioid-addiction vulnerability.

Type
Review Article
Information
CNS Spectrums , Volume 11 , Issue 11 , November 2006 , pp. 855 - 862
Copyright
Copyright © Cambridge University Press 2006

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