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Overlapping dimensional phenotypes of impulsivity and compulsivity explain co-occurrence of addictive and related behaviors

  • Jeggan Tiego (a1), Sanne Oostermeijer (a1) (a2), Luisa Prochazkova (a1) (a3), Linden Parkes (a1), Andrew Dawson (a1), George Youssef (a1) (a4) (a5), Erin Oldenhof (a1), Adrian Carter (a1), Rebecca A. Segrave (a1), Leonardo F. Fontenelle (a1) (a6) (a7) and Murat Yücel (a1)...



Impulsivity and compulsivity have been implicated as important transdiagnostic dimensional phenotypes with potential relevance to addiction. We aimed to develop a model that conceptualizes these constructs as overlapping dimensional phenotypes and test whether different components of this model explain the co-occurrence of addictive and related behaviors.


A large sample of adults (N = 487) was recruited through Amazon’s Mechanical Turk and completed self-report questionnaires measuring impulsivity, intolerance of uncertainty, obsessive beliefs, and the severity of 6 addictive and related behaviors. Hierarchical clustering was used to organize addictive behaviors into homogenous groups reflecting their co-occurrence. Structural equation modeling was used to evaluate fit of the hypothesized bifactor model of impulsivity and compulsivity and determine the proportion of variance explained in the co-occurrence of addictive and related behaviors by each component of the model.


Addictive and related behaviors clustered into 2 distinct groups: Impulse-Control Problems, consisting of harmful alcohol use, pathological gambling, and compulsive buying, and Obsessive-Compulsive-Related Problems, consisting of obsessive-compulsive symptoms, binge eating, and internet addiction. The hypothesized bifactor model of impulsivity and compulsivity provided the best empirical fit, with 3 uncorrelated factors corresponding to a general Disinhibition dimension, and specific Impulsivity and Compulsivity dimensions. These dimensional phenotypes uniquely and additively explained 39.9% and 68.7% of the total variance in Impulse-Control Problems and Obsessive-Compulsive-Related Problems.


A model of impulsivity and compulsivity that represents these constructs as overlapping dimensional phenotypes has important implications for understanding addictive and related behaviors in terms of shared etiology, comorbidity, and potential transdiagnostic treatments.


Corresponding author

*Correspondence regarding this article should be addressed to Jeggan Tiego, Brain and Mental Health Research Hub, 770 Blackburn Road, Clayton, Victoria 3800, Australia. (Email:


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Jeggan Tiego and Sanne Oostermeijer are both first authors.



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Overlapping dimensional phenotypes of impulsivity and compulsivity explain co-occurrence of addictive and related behaviors

  • Jeggan Tiego (a1), Sanne Oostermeijer (a1) (a2), Luisa Prochazkova (a1) (a3), Linden Parkes (a1), Andrew Dawson (a1), George Youssef (a1) (a4) (a5), Erin Oldenhof (a1), Adrian Carter (a1), Rebecca A. Segrave (a1), Leonardo F. Fontenelle (a1) (a6) (a7) and Murat Yücel (a1)...


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