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Neurochemical and Behavioral Effects Related to 5-HT1B/1D Receptors

Published online by Cambridge University Press:  07 November 2014

Mike Briley  and
Chantal Moret
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Abstract

The lack of selective agonists and antagonists for serotonin 5-HT1B/1D receptors has made it difficult to determine the neurochemical, behavioral, and clinical effects controlled by 5-HT1B/1D receptors. However, by combining data from various compounds with different receptor affinity profiles, it is possible to tentatively determine those effects that result from interactions at the 5-HT1B/1D receptors.

This discussion contains a review of the in vitro and in vivo neuropharmacology of the 5-HT1B/1D group of receptor subtypes, and attempts to identify their possible functions and potential implications in central nervous system disorders.

Type
Feature Article
Information
CNS Spectrums , Volume 3 , Issue 8: Serotonin Subsystems , September 1998 , pp. 22 - 29
Copyright
Copyright © Cambridge University Press 1998

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