Autism is a common neurodevelopmental disorder that affects an individual’s ability to communicate socially and emotionally. The incidence of autism among college students is increasing year by year, which causes trouble to their study and life. Therefore, it is of great significance to find effective intervention methods to improve the symptoms of college students with autism.

This study selected 30 students from colleges and universities who were diagnosed with autism as research objects, and were randomly divided into an experimental group and a control group. The experimental group received 8 weeks of music-guided imagination activity combined with multimodal exercise intervention, while the control group received conventional treatment. Both groups were evaluated by self-rating scales and professional assessment tools, and data were analyzed using SPSS23.0 software to understand the efficacy before and after the intervention.

The self-rating scale score of the experimental group after intervention was significantly higher than that before intervention (P<0.05), and significantly higher than that of the control group (P<0.01). In the professional assessment tool, the loneliness symptom status score of the experimental group was significantly improved compared with that before intervention (P<0.05), and was significantly lower than that of the control group (P<0.01).

Music-guided imagination activity combined with multimodal movement has a significant effect on college students with autism. The experimental group can better express emotions, enhance social skills, and improve physical coordination and spatial perception through music-guided imagination activities.

2022 Guangdong Ocean University Graduate Education Innovation Project (No.202213); 2022 Guangdong Ocean University teaching quality and teaching reform project (No.px-11223462).