Newcomers to the workplace in the post-epidemic era are often accompanied by maladaptive symptoms such as anxiety and depression. Due to their varying degrees of severity, a combination of psychosocial and pharmacologic treatments is essential.

In this study, 500 on-the-job new employees of a company were selected as research subjects, and they were randomly divided into the control group and the research group. The control group was treated with medication only, and the research group was treated with a combination of psychological intervention medication. The medication was chosen to be buspirone hydrochloride tablets 10 mg 3 times/d orally, and analyzed with the Hamilton Rating Scale for Anxiety (HAM-A) as a control, and finally analyzed using SPSS 22.0 for statistical analysis.

After 3 months of experimentation in the study, the anxiety scale score of new employees in the control group decreased from 23 to 17, and the anxiety scale score of new employees in the research group decreased from 24 to 12. In the research group, there was a significant difference in the psychological stress of new employees before and after the experiment (P<0.05). The experimental results show that the treatment has a more obvious alleviating effect on the depression and anxiety of new employees in the post-epidemic era, which means combining psychological intervention and medication.

The combination of psychotherapy and drug therapy in this study can significantly alleviate the depression and anxiety of new employees after the epidemic. It can also provide a reference for other company managers and promote the attention to the psychological state of employees.

Humanities and Social Science project of Guangdong University of Science and Technology (No. GKY-2021KYYBW-35).