Hostname: page-component-848d4c4894-mwx4w Total loading time: 0 Render date: 2024-06-21T07:09:18.429Z Has data issue: false hasContentIssue false
  • English
  • Français

Apparent porosity of porous bioceramics prepared with small organic foam spheres as the pore-making reagent

Published online by Cambridge University Press:  09 July 2018

Chuisheng Zeng ,
Xiaoming Chen ,
Yuhua Yan ,
Xiaoying Tang ,
Yilong Liang ,
Zhiqiang Zhao  and
Yanjun Zeng
Chuisheng Zeng
Affiliation:
College of Bio-Information, Chongqing University of Post & Telecommunication, Chongqing 400065, China
Xiaoming Chen
Affiliation:
Biomedical Materials and Engineering Center, Wuhan University of Technology, Wuhan 430070, China
Yuhua Yan
Affiliation:
Biomedical Materials and Engineering Center, Wuhan University of Technology, Wuhan 430070, China
Xiaoying Tang
Affiliation:
School of Life, Department of Biomedical Engineering, Beijing Institute of Technology, Beijing 100081, China
Yilong Liang
Affiliation:
College of Bio-Information, Chongqing University of Post & Telecommunication, Chongqing 400065, China
Zhiqiang Zhao
Affiliation:
College of Bio-Information, Chongqing University of Post & Telecommunication, Chongqing 400065, China
Yanjun Zeng*
Affiliation:
Biomedical Engineering Center, Beijing University of Technology, Beijing 100022, China
*
*E-mail: yjzeng@bjut.edu.cn
Get access Rights & Permissions [Opens in a new window]

Abstract

This study focuses on the main factors determining the apparent porosity of porous bioceramics prepared using small organic foam spheres as the pore-making reagent, in order to determine the best technical parameters for preparing porous bioceramics. In every experiment, only one of these factors (the time of heating, the sintering temperature, the mass ratio between small organic foam spheres and beta-tricalcium phosphate (β-TCP) powder, and the rate of the temperature rise) was changed, while the others were kept constant. In each case the apparent porosity was tested and the relation between the specific variable and apparent porosity was observed. Finally, the optimum technical parameters were deduced. The apparent porosity shows an inverse linear relation to the time of heating and the sintering temperature, and is approximately proportional to the mass ratio between the small organic foam spheres and the β-TCP powder and the rate of temperature rise. These factors have important influences on the apparent porosity. The optimum conditions were: heating time (soak time) 120 min, sintering temperature 850ºC, mass ratio 0.25, and a rate of temperature increase of 120ºC h–1.

Keywords

porous bioceramicsheating timetime of heat preservationsoak timesintering temperatureβ-tricalcium phosphaterate of temperature increase
Type
Research Article
Information
Clay Minerals , Volume 45 , Issue 4 , December 2010 , pp. 449 - 452
Copyright
Copyright © The Mineralogical Society of Great Britain and Ireland 2010

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Barralet, J.E., Grover, L., Gaunt, T., Wright, A.J. & Gibson, I.R. (2002) Preparation of macroporous calcium phosphate cement tissue engineering scaffold. Biomaterials, 23, 3063–3072.CrossRefGoogle ScholarPubMed
Gbureck, U., Grolms, O., Barralet, J.E., Grover, L.M. & Thull, R. (2003) Mechanical activation and cement formation of β-tricalcium phosphate. Biomaterials, 24, 4123–4131.CrossRefGoogle ScholarPubMed
Hench, L.L. & Polak, J.M. (2002) Third-generation biomedical materials. Science, 295, 1014–1017.CrossRefGoogle ScholarPubMed
Hulbert, S.F., Morrison, S.J. & Klawitter, J.J. (1972) Tissue reaction to three ceramics of porous and nonporous structures. Journal of Biomedical Materials Research, 6, 347–374.CrossRefGoogle ScholarPubMed
Ishaug, S.L., Crane, G.M., Miller, M.J., Yasko, A.W., Yaszemski, M.J. & Mikos, A.G. (1997) Bone formation by three-dimensional stromal osteoblast culture in biodegradable polymer scaffolds. Journal of Biomedical Materials Research, 36, 17–28.3.0.CO;2-O>CrossRefGoogle ScholarPubMed
John, A., Varma, H.K. & Kumari, T.V. (2003) Surface reactivity of calcium phosphate based ceramics in a cell culture system. Journal of Biomaterials Applications, 18, 63–78.CrossRefGoogle Scholar
Katti, K.S. (2004) Biomaterials in total joint replacement. Colloids and Surfaces B: Biointerfaces, 39, 133–142.CrossRefGoogle ScholarPubMed
Lee, Y.M., Yang, J.S. & Lim, Y.K. (2001) Tissue engineered growth of bone by marrow cell transplantation using porous calcium metaphosphate matrices. Journal of Biomedical Materials Research, 54, 216–223.3.0.CO;2-C>CrossRefGoogle ScholarPubMed
LeGeros, R.Z. (1993) Biodegradation and bioresorption of calcium phosphate ceramics. Clinical Materials, 14, 65–88.CrossRefGoogle ScholarPubMed
Lu, J.X., Flautre, B. & Anselme, K. (1997) Study of porous interconnection of bioceramic on cellular rehabilitation in vitro and in vivo . Biomaterials, 10, 583.Google Scholar
Ohgushi, H., Okamura, M., Yoshikawa, T., Inoue, K., Senpuku, N., Tamai, S. & Shors, E.C. (1992) Bone formation process in porous calcium carbonate and hydroxyapatite. Journal of Biomedical Materials Research, 26, 885–895.CrossRefGoogle ScholarPubMed
Radin, S.R. & Ducheyne, P. (1993) The effect of calcium phosphate ceramic composition and structure on in vitro behavior. Journal of Biomedical Materials Research, 27, 35–45.CrossRefGoogle ScholarPubMed
Takahashi, T., Yamamoto, M., Ioku, K. & Goto, S. (1997) Relationship between compressive strength and pore structure of hardened cement pastes. Advances in Cement Research, 9, 25–30.CrossRefGoogle Scholar
Zeng, C.S., Zhang, L., Zeng, Y.J., Chen, X.M. & Yan, Y.H. (2009) A new technique for preparation of porous bioceramic with controllable macrostructures. Clay Minerals, 44, 411–416.CrossRefGoogle Scholar