Hostname: page-component-8448b6f56d-dnltx Total loading time: 0 Render date: 2024-04-23T08:07:27.594Z Has data issue: false hasContentIssue false
  • English
  • Français

Troponin elevation in the setting of exercise-induced rhabdomyolysis in an athletic teenager

Published online by Cambridge University Press:  03 December 2019

Jacqueline Rausa ,
Ira Shetty  and
Rohit S. Loomba Open the ORCID record for Rohit S. Loomba [Opens in a new window]
Jacqueline Rausa
Affiliation:
Advocate Children’s Hospital, Chicago, IL, USA
Ira Shetty
Affiliation:
Advocate Children’s Hospital, Chicago, IL, USA
Rohit S. Loomba*
Affiliation:
Advocate Children’s Hospital, Chicago, IL, USA Chicago Medical School, Chicago, IL, USA
*
Author for correspondence: R. S. Loomba, Division of Pediatric Cardiology, Advocate Children’s Hospital, 4440 95th Street, Oak Lawn, IL 60453, USA. Tel: +1 708 684 6471; Fax: +1 708 684 5932; E-mail: loomba.rohit@gmail.com
Get access Rights & Permissions [Opens in a new window]

Abstract

Troponin levels are often obtained when chest pain is evaluated in the paediatric emergency department. Elevations in troponin levels can be due to different causes, and it is important to fully understand all of these possible causes to help streamline further evaluation and therapy. We present the case of a teenager who had two episodes of troponin elevation in the setting of rhabdomyolysis.

Keywords

Troponinrhabdomyolysismyocarditis
Type
Brief Report
Information
Cardiology in the Young , Volume 29 , Issue 12 , December 2019 , pp. 1552 - 1555
Copyright
© Cambridge University Press 2019 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Footnotes

This case report does have a greater number of figures and words than outlined in the instructions for authors. This has been discussed with Dr Jeffrey Jacobs who has said this is alright.

References

Westermeyer, ML, Eilbert, WP. Elevation of troponin I in athletes: a case report in a marathon runner. J Emerg Med 2008; 34: 175–178.10.1016/j.jemermed.2007.03.044CrossRefGoogle Scholar
Korff, S, Katus, HA, Giannitsis, E. Differential diagnosis of elevated troponins. Heart 2006; 92: 987–993.CrossRefGoogle ScholarPubMed
Alpert, JS, Thygesen, K, Antman, E, Bassand, JP. Myocardial infarction redefined – a consensus document of The Joint European Society of Cardiology/American College of Cardiology Committee for the redefinition of myocardial infarction. J Am Coll Cardiol 2000; 36: 959–969.Google Scholar
Nageh, T, Sherwood, RA, Harris, BM, Thomas, MR. Prognostic role of cardiac troponin I after percutaneous coronary intervention in stable coronary disease. Heart 2005; 91: 1181–1185.10.1136/hrt.2004.042911CrossRefGoogle ScholarPubMed
Lehrke, S, Steen, H, Sievers, HH, et al. Cardiac troponin T for prediction of short- and long-term morbidity and mortality after elective open heart surgery. Clin Chem 2004; 50: 1560–1567.CrossRefGoogle Scholar
Imazio, M, Demichelis, B, Cecchi, E, et al. Cardiac troponin I in acute pericarditis. J Am Coll Cardiol 2003; 42: 2144–2148.CrossRefGoogle ScholarPubMed
Missov, E, Mair, J. A novel biochemical approach to congestive heart failure: cardiac troponin T. Am Heart J 1999; 138: 95–99.CrossRefGoogle ScholarPubMed
Giannitsis, E, Muller-Bardorff, M, Kurowski, V, et al. Independent prognostic value of cardiac troponin T in patients with confirmed pulmonary embolism. Circulation 2000; 102: 211–217.10.1161/01.CIR.102.2.211CrossRefGoogle ScholarPubMed
Apple, FS, Murakami, MM, Pearce, LA, Herzog, CA. Predictive value of cardiac troponin I and T for subsequent death in end-stage renal disease. Circulation 2002; 106: 2941–2945.CrossRefGoogle Scholar
Bonnefoy, E, Godon, P, Kirkorian, G, Chabaud, S, Touboul, P. Significance of serum troponin I elevation in patients with acute aortic dissection of the ascending aorta. Acta Cardiol 2005; 60: 165–170.10.2143/AC.60.2.2005027CrossRefGoogle ScholarPubMed
Rifai, N, Douglas, PS, O’Toole, M, Rimm, E, Ginsburg, GS. Cardiac troponin T and I, echocardiographic [correction of electrocardiographic] wall motion analyses, and ejection fractions in athletes participating in the Hawaii Ironman Triathlon. Am J Cardiol 1999; 83: 1085–1089.CrossRefGoogle Scholar
Lavoinne, A, Hue, G. Serum cardiac troponins I and T in early posttraumatic rhabdomyolysis. Clin Chem 1998; 44: 667–668.Google Scholar
Neumayr, G, Gaenzer, H, Pfister, R, et al. Plasma levels of cardiac troponin I after prolonged strenuous endurance exercise. Am J Cardiol 2001; 87: 369–371, A310.CrossRefGoogle ScholarPubMed
Koller, A. Exercise-induced increases in cardiac troponins and prothrombotic markers. Med Sci Sports Exerc 2003; 35: 444–448.CrossRefGoogle ScholarPubMed
Rowe, WJ. Extraordinary unremitting endurance exercise and permanent injury to normal heart. Lancet 1992; 340: 712–714.10.1016/0140-6736(92)92243-9CrossRefGoogle ScholarPubMed
Laslett, L, Eisenbud, E, Lind, R. Evidence of myocardial injury during prolonged strenuous exercise. Am J Cardiol 1996; 78: 488–490.CrossRefGoogle ScholarPubMed
Punukollu, G, Gowda, RM, Khan, IA, et al. Elevated serum cardiac troponin I in rhabdomyolysis. Int J Cardiol 2004; 96: 35–40.10.1016/j.ijcard.2003.04.053CrossRefGoogle ScholarPubMed
Wongrakpanich, S, Kallis, C, Prasad, P, et al. Prevalence of false positive troponin I in elderly patients with rhabdomyolysis. Geriatr Gerontol Int 2017; 17: 1137–1140.CrossRefGoogle ScholarPubMed
Li, SF, Zapata, J, Tillem, E. The prevalence of false-positive cardiac troponin I in ED patients with rhabdomyolysis. Am J Emerg Med 2005; 23: 860–863.10.1016/j.ajem.2005.05.008CrossRefGoogle ScholarPubMed
Hyytia, H, Heikkila, T, Hedberg, P, Puolakanaho, T, Pettersson, K. Skeletal troponin I cross-reactivity in different cardiac troponin I assay versions. Clin Biochem 2015; 48: 313–317.CrossRefGoogle ScholarPubMed