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Short-term renal support in postoperative repair of tetralogy of Fallot in the paediatric intensive care unit: can we predict those who need it?

Published online by Cambridge University Press:  10 June 2014

Michael J. Griksaitis ,
Rebekah R. Kemp ,
Robert J. Dyer ,
James P. Gnanapragasam ,
Nicola Viola ,
Iain Macintosh  and
Kim Sykes
Michael J. Griksaitis*
Affiliation:
Department of Child Health, Paediatric Intensive Care, University Hospital Southampton, SouthamptonUnited Kingdom
Rebekah R. Kemp
Affiliation:
Department of Child Health, Paediatric Intensive Care, University Hospital Southampton, SouthamptonUnited Kingdom
Robert J. Dyer
Affiliation:
Department of Mathematics, Manchester University, ManchesterUnited Kingdom
James P. Gnanapragasam
Affiliation:
Department of Paediatric Cardiology, University Hospital SouthamptonSouthampton, United Kingdom
Nicola Viola
Affiliation:
Department of Cardiothoracic Surgery, University Hospital Southampton, Southampton, United Kingdom
Iain Macintosh
Affiliation:
Department of Child Health, Paediatric Intensive Care, University Hospital Southampton, SouthamptonUnited Kingdom
Kim Sykes
Affiliation:
Department of Child Health, Paediatric Intensive Care, University Hospital Southampton, SouthamptonUnited Kingdom
*
Correspondence to: Dr M. J. Griksaitis, MBBS (Hons), MRCPCH, PGDipMedEd, Paediatric Intensive Care Unit, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, United Kingdom. Tel: +44 23 8077 7222; Fax: +44 23 80 794526; E-mail: m.j.griksaitis@doctors.org.uk
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Abstract

Introduction

Fluid balance and renal function can be difficult to manage in the postoperative infant with tetralogy of Fallot. High fluid volumes are often needed to maintain cardiac output.

Aims

To stratify patients at risk for advanced renal support following tetralogy of Fallot repair.

Methods

Retrospective analysis of all consecutive tetralogy of Fallot cases operated at a single centre in a 3-year period.

Results

A total of 41 children were identified. All cases had loop diuretics administered. Of the cases, 17% required support with a peritoneal dialysis catheter, with only one complication of peritoneal dialysis catheter blockage. The mean length of paediatric intensive care unit stay in those receiving peritoneal dialysis catheter insertion was prolonged by an additional mean of 6 days (p<0.001). No statistical significance was found between those children requiring peritoneal dialysis and those who did not when considering patient age and weight at time of repair, cardiopulmonary bypass and aortic cross clamp times, the presence of a transannular patch, or junctional ectopic tachycardia. However, volume requirement of more than 35 ml/kg in the first 12 hours following repair did increase the likelihood to need peritoneal dialysis (p<0.0001). Furthermore, the higher the peak creatinine, the longer the stay on intensive care (p<0.01).

Conclusions

Peritoneal dialysis is an effective method of dealing with fluid balance in children after tetralogy of Fallot repair, with minimal complications. Early consideration should be given to peritoneal dialysis when it is clear that high fluid volumes are required postoperatively.

Keywords

Tetralogy of Fallotperitoneal dialysiscongenital heart diseasecardiac surgerypaediatric intensive carerenal functionfluid resuscitation
Type
Original Articles
Information
Cardiology in the Young , Volume 25 , Issue 4 , April 2015 , pp. 760 - 764
Copyright
© Cambridge University Press 2014 

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