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Rhabdomyoma of the interventricular septum presenting as a Brugada phenocopy

  • Timothy Nguyen (a1), John Smythe (a1) and Adrian Baranchuk (a1)


Brugada syndrome is a channelopathy characterised electrocardiographically by distinctive coved ST-segment elevation in the right precordial leads and is associated with a predisposition for sudden death secondary to ventricular arrhythmias in otherwise healthy patients. Previously known as Brugada-like patterns, Brugada phenocopies include agents and conditions that mimic true Brugada syndrome, presenting with an acquired Brugada Type-1 ECG pattern. We describe the first reported case of a 17-month-old female with an asymptomatic rhabdomyoma of the interventricular septum that presented as a Brugada phenocopy.


Corresponding author

Correspondence to: Dr A. Baranchuk, MD FACC, Associate Professor of Medicine, Cardiac Electrophysiology and Pacing, Kingston General Hospital K7L 2V7, Queen's University, Canada. Tel: 613 549 6666 ext 3801; Fax: 613 548 1387; E-mail:


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1.Antzelevitch, C, Brugada, P, Borggrefe, M, et al. Brugada syndrome: report of the second consensus conference: endorsed by the heart rhythm society and the European Heart Rhythm Association. Circulation 2005; 111: 659670.
2.Riera, ARP, Uchida, AH, Schapachnik, E, et al. Propofol infusion syndrome and Brugada syndrome electrocardiographic phenocopy. Cardiol J 2010; 17: 130135.
3.Arce, M, Riera, ARP, Femenia, F, Baranchuk, A. Brugada electrocardiographic phenocopy in a patient with chronic chagasic cardiomyopathy. Cardiol J 2010; 17: 525527.
4.Sabatine, MS, Colucci, WS, Schoen, FJ. Primary tumors of the heart. In: Libby P, Bonow RO, Zipes DP, Mann DL (eds). Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th edn. Saunders, Philadelphia, 2007; 1751.
5.Marx, GR, Flyer, DC. Cardiac tumors. In: Keane JF, Lock JE, Fyler DC (eds). Nadas’ Pediatric Cardiology, 2nd edn. Saunders, Philadelphia, 2006; 825826.
6.Amonkar, GP, Kandalkar, BM, Balasubramanian, M. Cardiac rhabdomyoma. Cardiovasc Pathol 2009; 18: 313314.
7.Nakamura, K, Funabashi, N, Miyauchi, H, et al. Hemangioma located just above the left main coronary artery, in a subject who had cardiac arrest due to ventricular fibrillation, led to a diagnosis of Brugada syndrome. Int J Cardiol 2008; 127: 437441.
8.Tarin, N, Farre, J, Rubio, JM, Tunon, J, Castro-Dorticos, J. Brugada-like electrocardiographic pattern in a patient with a mediastinal tumor. PACE 1999; 22: 12641266.
9.Junttila, MJ, Gonzalez, M, Lizotte, E, et al. Induced brugada-type electrocardiogram, a sign for imminent malignant arrhythmias. Circulation 2008; 117: 18901893.



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