Hostname: page-component-848d4c4894-ttngx Total loading time: 0 Render date: 2024-05-04T09:17:24.628Z Has data issue: false hasContentIssue false
  • English
  • Français

Erythrocytosis and severe asphyxia: two different causes of neonatal myocardial infarction

Published online by Cambridge University Press:  07 February 2013

Elio Caruso ,
Alfredo Di Pino ,
Daniela Poli ,
Lucia Manuri  and
Paolo Guccione
Elio Caruso*
Affiliation:
Centro Cardiologico Pediatrico del Mediterraneo, San Vincenzo Hospital, Taormina (ME), Italy
Alfredo Di Pino
Affiliation:
Centro Cardiologico Pediatrico del Mediterraneo, San Vincenzo Hospital, Taormina (ME), Italy
Daniela Poli
Affiliation:
Centro Cardiologico Pediatrico del Mediterraneo, San Vincenzo Hospital, Taormina (ME), Italy
Lucia Manuri
Affiliation:
Centro Cardiologico Pediatrico del Mediterraneo, San Vincenzo Hospital, Taormina (ME), Italy
Paolo Guccione
Affiliation:
Centro Cardiologico Pediatrico del Mediterraneo, San Vincenzo Hospital, Taormina (ME), Italy
*
Correspondence to: Dr E. Caruso, MD, Centro Cardiologico Pediatrico del Mediterraneo, San Vincenzo Hospital, Contrada Sirina, 98039 Taormina (ME), Italy. Tel: +390942579558; Fax: +390942579573; E-mail: carusoelio@gmail.com
Get access Rights & Permissions [Opens in a new window]

Abstract

Neonatal acute myocardial infarction is a rare event that carries a high mortality rate. We describe the cases of two newborns who survived acute myocardial infarction and discuss the management. The first neonate was born with severe asphyxia and left ventricular myocardial infarction with ventricular tachycardia. In this patient, systemic flow was maintained by right-to-left shunting through the patent ductus arteriosus. The second neonate presented with a haematocrit of 80% and an inferolateral myocardial infarction. Intensive treatment of low cardiac output syndrome led to survival of both high-risk neonates. In the follow-up, at 48 and 4 months, respectively, ventricular function recovered in both patients.

Keywords

Myocardial ischaemiaventricular tachycardiaduct assistanceventricular hypertrophypolycythaemia
Type
Brief Reports
Information
Cardiology in the Young , Volume 24 , Issue 1 , February 2014 , pp. 178 - 181
Copyright
Copyright © Cambridge University Press 2013 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. De Vetten, L, Bergman, KA, Elzenga, NJ, Van Melle, JP, Timmer, A, Bartelds, B. Neonatal myocardial infarction or myocarditis? Pediatr Cardiol 2011; 32: 492–497.CrossRefGoogle ScholarPubMed
2. Murugan, SJ, Gnanapragasam, J, Vettukattil, J. Acute myocardial infarction in the neonatal period. Cardiol Young 2002; 12: 411–413.CrossRefGoogle ScholarPubMed
3. Clark, AB, Stokes, T, Krous, HF, Carbine, D. Myocardial infarction in a newborn heterozygous for the MTHFR C677T mutation. Pediatr Dev Pathol 2012; 15: 232–236.CrossRefGoogle Scholar
4. Abbal, J, Paranon, S, Brierre, G, Dulac, Y, Casper, C, Acar, P. Myocardial infarction in a newborn from a diabetic mother. Cardiol Young 2010; 20: 451–454.CrossRefGoogle Scholar
5. Poonai, N, Kornecki, A, Buffo, I, Pepelassis, D. Neonatal myocardial infarction secondary to umbilical venous catheterization: a case report and review of the literature. Paediatr Child Health 2009; 14: 539–541.CrossRefGoogle ScholarPubMed
6. Farooqi, KM, Sutton, N, Weinstein, S, Menegus, M, Spindola-Franco, H, Pass, RH. Neonatal myocardial infarction: case report and review of the literature. Congenit Heart Dis 2012, April 27.CrossRefGoogle ScholarPubMed
7. Rossi, C, Randi, ML, Zerbinati, P, Rinaldi, V, Girolami, A. Acute coronary disease in essential thrombocythemia and polycythemia vera. J Intern Med 1998; 244: 49–53.CrossRefGoogle ScholarPubMed
8. Holtz, J. Myocardial hypertrophy after myocardial infarct: what is the significance of phenotype changes in cardiocytes? Herz 1993; 18: 387–394.Google ScholarPubMed
9. Samson, FN, Bonnet, M, Heimburger, M, et al. Left ventricular alterations in a model of fetal left ventricular overload. Pediatr Res 2000; 48: 43–49.CrossRefGoogle Scholar
10. de Almeida, A, McQuinn, T, Sedmera, D. Increased ventricular preload is compensated by myocyte proliferation in normal and hypoplastic fetal chick left ventricle. Circ Res 2007; 10: 1363–1370.CrossRefGoogle Scholar