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Ductal constriction during dexamethasone treatment in an anti-SSA-antibody-exposed fetus with signs of myocardial inflammation

Published online by Cambridge University Press:  18 April 2016

Lauren Talemal ,
Laura Olivieri  and
Anita Krishnan
Lauren Talemal*
Affiliation:
Department of Cardiology, Children’s National Medical Center, Washington, District of Columbia, United States of America
Laura Olivieri
Affiliation:
Department of Cardiology, Children’s National Medical Center, Washington, District of Columbia, United States of America
Anita Krishnan
Affiliation:
Department of Cardiology, Children’s National Medical Center, Washington, District of Columbia, United States of America
*
Correspondence to: L. Talemal, Department of Cardiology, Children’s National Medical Center, 111 Michigan Avenue NW, Suite WW3-200, Washington, DC 20010, United States of America. Tel: +1 202 476 2020; Fax: +1 202 476 5700; E-mail: LTalemal@childrensnational.org
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Abstract

This report describes the clinical course and multi-modality imaging findings in an anti-SSA-antibody-exposed fetus with suspected myocardial inflammation. Postnatal cardiac MRI – using fast acquisition, free-breathing with feed-and-swaddle technique – was used to evaluate for myocardial fibrosis/inflammation. This is the first published report, to our knowledge, of ductal constriction temporally associated with oral dexamethasone therapy in an anti-SSA-antibody-exposed fetus and of the use of this unique postnatal MRI protocol in this setting.

Keywords

Anti-SSA antibodiesductus arteriosus constrictionsteroids
Type
Brief Reports
Information
Cardiology in the Young , Volume 26 , Issue 5 , June 2016 , pp. 1021 - 1024
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Copyright
© Cambridge University Press 2016 

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