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Does obesity affect the short-term outcomes after cardiothoracic surgery in adolescents with congenital heart disease?

Published online by Cambridge University Press:  09 January 2020

Richard U. Garcia Open the ORCID record for Richard U. Garcia [Opens in a new window] ,
Preetha L. Balakrishnan  and
Sanjeev Aggarwal
Richard U. Garcia*
Affiliation:
Division of Cardiology, Carman and Ann Adams Department of Pediatrics, Children’s Hospital of Michigan, Wayne State University School of Medicine 3901 Beaubien Blvd, Detroit, MI48201-2119, USA
Preetha L. Balakrishnan
Affiliation:
Division of Cardiology, Carman and Ann Adams Department of Pediatrics, Children’s Hospital of Michigan, Wayne State University School of Medicine 3901 Beaubien Blvd, Detroit, MI48201-2119, USA
Sanjeev Aggarwal
Affiliation:
Division of Cardiology, Carman and Ann Adams Department of Pediatrics, Children’s Hospital of Michigan, Wayne State University School of Medicine 3901 Beaubien Blvd, Detroit, MI48201-2119, USA
*
Author for correspondence: R. U. Garcia, MD, Division of Cardiology, Carman and Ann Adams Department of Pediatrics, Children’s Hospital of Michigan, Wayne State University School of Medicine, 3901 Beaubien Blvd, Detroit, MI48201-2119, USA. Tel: +1(313) 966-7277 (Business); Fax: +1(313) 993-0894; E-mail: rgarcias@dmc.org
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Abstract

Background:

Obesity is a modifiable, independent risk factor for mortality and morbidity after cardiovascular surgery in adults. Our objective was to evaluate the impact of obesity on short-term outcomes in adolescents undergoing surgery for congenital heart disease (CHD).

Methods:

This retrospective chart review included patients 10–18 years of age who underwent CHD surgery. Our exclusion criteria were patients with a known genetic syndrome, heart transplantation, and patients with incomplete medical records. The clinical data collected included baseline demographics and multiple perioperative variables. Charting the body mass index in the Centers for Disease Control and Prevention growth curves, the entire cohort was divided into three categories: obese (>95th percentile), overweight (85th–95th percentile), and normal weight (<85th percentile). The composite outcome included survival, arrhythmias, surgical wound infection, acute neurologic injury, and acute kidney injury.

Results:

The study cohort (n = 149) had a mean standard deviation (SD), body mass index (BMI) of 22.6 ± 6.5 g/m2, and 65% were male. There were 27 obese (18.1%), 24 overweight (16.1%), and 98 normal weight (65.8%) patients. Twenty-seven (18%) patients had composite adverse outcomes. Overweight and obese patients had significantly higher adverse outcomes compared with normal weight patients (odds ratio (OR): 2.9; confidence interval (CI): 1–8.5, p = 0.04 and OR: 3; CI: 1–8.5, p = 0.03, respectively). In multivariate analysis, obesity was an independent predictor of adverse outcome in our cohort (p = 0.04).

Conclusions:

Obesity is associated with short-term adverse outcome and increased health resource utilisation in adolescents following surgery for CHD. Further studies should evaluate if intervention in the preoperative period can improve outcomes in this population.

Keywords

Obesitypost-operative outcomescongenital heart diseaseadolescents
Type
Original Article
Information
Cardiology in the Young , Volume 30 , Issue 3 , March 2020 , pp. 372 - 376
Copyright
© Cambridge University Press 2020

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