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Synchronous Lumbar Disc Herniation in Adult Twins. Case Report

Published online by Cambridge University Press:  02 December 2014

Ratan Bhardwaj  and
Rajiv Midha
Ratan Bhardwaj
Affiliation:
Division of Neurosurgery and Neuroscience Research Program, Sunnybrook & Women's College Health Sciences Centre, Department of Surgery, University of Toronto, Toronto and Division of Neurosurgery, Department of Clinical Neurosciences, University of Calgary, Calgary, AB, Canada
Rajiv Midha
Affiliation:
Division of Neurosurgery and Neuroscience Research Program, Sunnybrook & Women's College Health Sciences Centre, Department of Surgery, University of Toronto, Toronto and Division of Neurosurgery, Department of Clinical Neurosciences, University of Calgary, Calgary, AB, Canada
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Abstract

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Objective:

To report an unusual case of large synchronous lumbar disc herniation in adult twins.

Methods:

Case report and relevant literature review.

Results:

The authors report a case of adult female monozygotic twins who synchronously presented with huge lumbar disc herniation. Rather than being a curious coincidence, this case highlights the potential importance of hereditary factors in the causation of lumbar disc degeneration. The relevant literature regarding the role of genetic factors and their relationship to other risk factors in lumbar disc degeneration is reviewed and discussed.

Conclusion:

Synchronous lumbar disc herniation in adult twins is a rare event. It, however, sheds light on the role of genetic factors in disc degeneration.

Type
Other
Information
Canadian Journal of Neurological Sciences , Volume 31 , Issue 4 , November 2004 , pp. 554 - 557
Copyright
Copyright © The Canadian Journal of Neurological 2004

References

1. Gunzburg, R, Fraser, RD, Fraser, GA. Lumbar intervertebral disc prolapse in teenage twins. A case report and review of the literature. J Bone Joint Surg Br 1990;72(5):914–916.Google Scholar
2. Matsui, H, Tsuji, H, Terahata, N. Juvenile lumbar herniated nucleus pulposus in monozygotic twins. Spine 1990;15(11):1228–1230.CrossRefGoogle ScholarPubMed
3. Battie, MC, Haynor, DR, Fisher, LD, et al. Similarities in degenerative findings on magnetic resonance images of the lumbar spines of identical twins. J Bone Joint Surg (Am) 1995;77(11):1662–1670.Google Scholar
4. Battie, MC, Videman, T, Gibbons, LE, et al. 1995 Volvo Award in Clinical Sciences. Determinants of lumbar disc degeneration. A study relating lifetime exposures and magnetic resonance imaging findings in identical twins. Spine 1995;20(24):2601–2612.CrossRefGoogle ScholarPubMed
5. Sambrook, PN, MacGregor, AJ, Spector, TD. Genetic influences on cervical and lumbar disc degeneration: a magnetic resonance imaging study in twins. Arthritis Rheum 1999;42(2):366–372.Google Scholar
6. Videman, T, Leppavuori, J, Kaprio, J, et al. Intragenic polymorphisms of the vitamin D receptor gene associated with intervertebral disc degeneration. Spine 1998;23(23):2477–2485.Google Scholar
7. Varughese, G, Quartey, GR. Familial lumbar spinal stenosis with acute disc herniations. Case reports of four brothers. J Neurosurg 1979;51(2):234–236.Google Scholar
8. Heikkila, JK, Koskenvuo, M, Heliovaara, M, et al. Genetic and environmental factors in sciatica. Evidence from a nationwide panel of 9365 adult twin pairs. Ann Med 1989;21(5):393–398.CrossRefGoogle ScholarPubMed
9. Matsui, H, Kanamori, M, Ishihara, H, et al. Familial predisposition for lumbar degenerative disc disease. A case-control study. Spine 1998;23(9):1029–1034.Google Scholar
10. Matsui, H, Terahata, N, Tsuji, H, Hirano, N, Naruse, Y. Familial predisposition and clustering for juvenile lumbar disc herniation. Spine 1992;17(11):1323–1328.CrossRefGoogle ScholarPubMed