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Successful treatment of pediatric stroke with recombinant tissue plasminogen activator (rt-PA): a case report and review of the literature

  • Shirra Cremer (a1), Yaniv Berliner (a2), David Warren (a3) and Andrew E. Jones (a2)

Abstract

Pediatric stroke is a rare disorder with a paucity of evidence-based treatment options, and can result in significant morbidity and mortality. In contrast to adult acute ischemic stroke, where the use of recombinant tissue plasminogen activator (rt-PA) has been studied in several large, randomized clinical trials, no high-level evidence exists for the use of thrombolytics in children with stroke. We report a case of a 15-year-old girl who suffered an acute ischemic stroke and had a dramatic improvement in symptoms following the administration of intravenous rt-PA.

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Copyright

Corresponding author

Emergency Department, Rm. E1-124, London Health Sciences Centre, Victoria Campus, 800 Commissioners Rd. E., London ON N6A 5W9; jonesmd@gmail.com

References

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Keywords

Successful treatment of pediatric stroke with recombinant tissue plasminogen activator (rt-PA): a case report and review of the literature

  • Shirra Cremer (a1), Yaniv Berliner (a2), David Warren (a3) and Andrew E. Jones (a2)

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