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Mechanisms of insecticide resistance in Aedes aegypti (L.) (Diptera: Culicidae) from Puerto Rico

Published online by Cambridge University Press:  10 July 2009

J. Hemingway ,
R. G. Boddington ,
J. Harris  and
S. J. Dunbar
J. Hemingway*
Affiliation:
London School of Hygiene and Tropical Medicine, Keppel Street, Gower Street, London, WCIE 7HT, UK
R. G. Boddington
Affiliation:
London School of Hygiene and Tropical Medicine, Keppel Street, Gower Street, London, WCIE 7HT, UK
J. Harris
Affiliation:
London School of Hygiene and Tropical Medicine, Keppel Street, Gower Street, London, WCIE 7HT, UK
S. J. Dunbar
Affiliation:
I.C.I., Jealott's Hill Research Station, Bracknell, Berks, RG12 6EY, UK
*
*To whom all correspondence should be sent.
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Abstract

A strain of Aedes aegypti (L.) was collected in Rio Piedras, Puerto Rico, in 1987 and reared through to the F2 generation. The strain was shown to be heterozygous for resistance to a range of pyrethroids, but there was no evidence of organophosphate and carbamate resistance. Biochemical studies indicated that the pyrethroid resistance was not metabolically based. Electrophysiological studies at the neuromuscular junction of resistant insects indicated that a kdr (nerve insensitivity) type mechanism was operating in this strain. It is not known whether this mechanism was selected by earlier DDT exposure or by the recent ultra-low-volume applications of pyrethroids.

Type
Original Articles
Information
Bulletin of Entomological Research , Volume 79 , Issue 1 , March 1989 , pp. 123 - 130
Copyright
Copyright © Cambridge University Press 1989

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