Skip to main content Accessibility help

Antifeedant activity of xanthohumol and supercritical carbon dioxide extract of spent hops against stored product pests

  • J. Jackowski (a1), M. Hurej (a1), E. Rój (a2), J. Popłoński (a3), L. Kośny (a1) and E. Huszcza (a3)...


Xanthohumol, a prenylated flavonoid from hops, and a supercritical carbon dioxide extract of spent hops were studied for their antifeedant activity against stored product insect pests: Sitophilus granarius L., Tribolium confusum Duv. and Trogoderma granarium Everts. Xanthohumol exhibited medium deterrent activity against the adults of S. granarius L. and larvae of T. confusum Duv. The spent hops extract was more active than xanthohumol towards the adults of T. confusum Duv. The potential application of the crude spent hops extract as a feeding deterrent against the stored product pests is proposed.


Corresponding author

* Author for correspondence Phone: +48713201693 Fax: +48713201748 E-mail:


Hide All
Bartmańska, A., Tronina, T., Popłoński, J. & Huszcza, E. (2013) Biotransformations of prenylated hop flavonoids for drug discovery and production. Current Drug Metabolism 14, 10831097.
Biendl, M. (2007) Development of new plant extracts rich in hop polyphenols. pp. 8–9 in Proceedings of the 31st EBC (European Brewing Convention) Congress, 06-10.05.2007, Venice.
Chadwick, L.R., Pauli, G.F. & Farnsworth, N.R. (2006) The pharmacognosy of Humulus lupulus L. (hops) with an emphasis on estrogenic properties. Phytomedicine 13, 119131.
Coleoptera Poloniae. Information System about Beetles of Poland — KFP (Catalogue of Fauna of Poland) 2011, accessed in July 2014. Database browser
Dancewicz, K., Wiśniewska, E., Lagiera, M., Anioł, M. & Gabryś, B. (2011) Effect of spent hop extracts on the probing and settling behaviour of Myzus persicae (Sulzer, 1776). Aphids and Other Hemipterous Insects 17, 121127.
Gökçe, A., Stelinski, Ł.L., Whalon, M.E. & Gut, L.J. (2009) Toxicity and antifeedant activity of selected plant extracts against larval obliquebanded leafroller, Choristoneura rosaceana (Harris). Open Entomology Journal 3, 3036.
Gökçe, A., Isaacs, R. & Whalon, M.E. (2012) Dose-response relationships for the antifeedant effects of Humulus lupulus extracts against larvae and adults of the Colorado potato beetle. Pest Management Science 68(3), 476481.
Guo-qing, H., Hao-ping, X., Qi-he, C., Hui, R., Zhao-yue, W. & Lonseny, T. (2005) Optimization of conditions for supercritical fluid extraction of flavonoids from hops (Humulus lupulus L.). Journal of Zhejiang University Science B 10, 9991004.
Harborne, J.B. & Grayer, R.J. (1993) Flavonoids and insects. pp. 589618 in Harborne, J.B. (Ed.) The Flavonoids. London, Chapman and Hall.
Iwashina, T. (2003) Flavonoid function and activity to plants and other organisms. Biological Sciences in Space 17, 2444.
Jones, G., Campbell, C.A.M., Hardie, J., Pickett, J.A., Pye, B.J. & Wadhams, L.J. (2003) Integrated management of two-spotted spider mite Tetranychus urticae on hops using hop ß-acids as an antifeedant together with the predatory mite Phytoseiulus persimilis . Biocontrol Science and Technology 13(2), 241252.
Larson, E.L., Yu, , Rosa, R.Y., Lee, , Olga, A., Price, S., Haas, G.J. & Johnson, E.A. (1996) Antimicrobial activity of hop extracts against Listeria monocytogenes in media and in food. International Journal of Food Microbiology 33, 195207.
Nawrot, J., Bloszyk, E., Harmatha, J., Novotny, L. & Drozdz, B. (1986) Action of antifeedants of plant origin on beetles infesting stored products. Acta Entomologica Bohemslovaca 83, 327335.
Nawrot, J., Dams, I. & Wawrzeńczyk, Cz. (2009) Feeding deterrent activity of terpenoid lactones with a p-menthane system against stored-product pests. Journal of Stored Products Research 45, 221225.
Powell, G., Hardie, J. & Pickett, J.A. (1997) Laboratory evaluation of antifeedant compounds for inhibiting settling by cereal aphids. Entomologia Experimentalis et Applicata 84, 189193.
Simmonds, M.S.J. (2001) Importance of flavonoids in insect-plant interactions: feeding and oviposition. Phytochemistry 56, 245–52.
Simmonds, M.S.J. (2003) Flavonoid–insect interactions: recent advances in our knowledge. Phytochemistry 64, 2130.
Stevens, J.F. & Page, J.E. (2004) Xanthohumol and related prenylflavonoids from hops and beer: to your good health! Phytochemistry 65, 13171330.
Stevens, J.F., Ivancic, M., Hsu, V. & Deinzer, M.L. (1997) Prenylflavonoids from Humulus lupulus . Phytochemistry 44, 15751585.
Stevens, J.F., Taylor, A.W. & Deinzer, M.L. (1999) Quantitative analysis of xanthohumol and related prenylflavonoids in hops and beer by liquid chromatography-tandem mass spectrometry. Journal of Chromatography A 832, 97107.
Strathmann, J. & Gerhäuser, C. (2012) Anti-proliferative and apoptosis-inducing properties of xanthohumol, a prenylated chalcone from hops (Humulus lupulus L.). pp. 6993 in Diederich, M. & Noworyta, K. (Eds). Natural Compounds as Inducers of Cell Death, Dordrecht, Springer.
War, A.R., Paulraj, M.G., Ahmad, T., Buhroo, A.A., Hussain, B., Ignacimuthu, S. & Sharma, H.C. (2012) Mechanisms of plant defense against insect herbivores. Plant Signaling and Behavior 7(10), 13061320.
Zanoli, P. & Zavatti, M. (2008) Pharmacognostic and pharmacological profile of Humulus lupulus L. Journal of Ethnopharmacology 116, 383396.



Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed