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Hormones of reproduction in farm animals

Published online by Cambridge University Press:  02 September 2010

R.B. Heap  and
G. Jenkin
G. Jenkin
Affiliation:
ARC Institute of Animal PhysiologyBabraham, Cambridge, CB2 4AT.
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Extract

Profiles of the blood concentration of the hormones of reproduction during the oestrous cycle and pregnancy have now been described in all farm animals. Advances in this field have been facilitated by the advent of highly sensitive radioimmunoassays of steroid and protein hormones in biological fluids (see Jaffe and Behrman, 1974). This paper summarizes the hormone changes that are normally associated with ovulation, the establishment and maintenance of gestation, and the onset of parturition. Emphasis will be given to progesterone and oestrogen in view of their important role in gestation and because we shall consider later the possible diagnostic or predictive value of their concentrations in the assessment of reproductive performance.

Type
Research Article
Information
BSAP Occasional Publication , Volume 1: The Use of Blood Metabolites in Animal Production , January 1978 , pp. 13 - 29
Copyright
Copyright © British Society of Animal Production 1978

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References

REFERENCES

Ash, R.W., Challis, J.R.G., Harrison, F.A., Heap, R.B., Illingworth, D.V., Perry, J.S. and Poyser, N.L. 1973. Hormonal control of pregnancy and parturition; a comparative analysis. In Foetal and Neonatal Physiology (ed. Comline, R.S., Cross, K.W., Dawes, G.S. and Nathanielsz, P.W.), pp. 551–561. University Press, Cambridge.Google Scholar
Ash, R.W. and Heap, R.B. 1973. The induction and synchronization of parturition in sows treated with I.C.I. 79,939, an analogue of prostaglandin F2α. J. agric. Sci., Camb. 81: 365–368.CrossRefGoogle Scholar
Ash, R.W. and Heap, R.B. 1975. Oestrogen, progesterone and corticosteroid concentrations in peripheral plasma of sows during pregnancy, parturition, lactation and after weaning. J. Endocr. 64: 141–154.CrossRefGoogle ScholarPubMed
Bassett, J.M., Oxborrow, T.J., Smith, I.D. and Thoeburn, G.D. 1969. The concentration of progesterone in the peripheral plasma of the pregnant ewe. J. Endocr. 45: 449–457.CrossRefGoogle ScholarPubMed
Bassett, J.M. and Thorburn, G.D. 1973. Circulating levels of progesterone and corticosteroids in the pregnant ewe and its foetus. In The Endocrinology of Pregnancy and Parturition, (ed. Pierrepoint, C.G.), pp. 126–140. Alpha Omega Alpha, Cardiff.Google Scholar
Bedford, C.A., Challis, J.R.G., Harrison, F.A. and Heap, R.B. 1972a. The role of oestrogens and progesterone in the onset of parturition in various species. J. Reprod. Fert. Suppl. 16: 1–24.Google ScholarPubMed
Bedford, C.A., Harrison, F.A. and Heap, R.B. 1972b. The metabolic clearance rate and production rate of progesterone and the conversion of progesterone to 20α-hydroxypregn-4-en-3-one in the sheep. J. Endocr. 55: 105–118.CrossRefGoogle Scholar
Bindon, B.M. and Turner, H.N. 1974. Plasma LH of the prepubertal lamb: a possible early indicator of fecundity. J. Reprod. Fert. 39: 85–88.CrossRefGoogle Scholar
Bryant, G.D., Linzell, J.L. and Greenwood, F.C. 1970. Plasma prolactin in goats measured by radioimmunoassay: the effects of teat stimulation, mating behaviour, fasting and of oxytocin, insulin and glucose injections. Hormones 1: 26–35.Google ScholarPubMed
Cerini, M., Findlay, J.K. and Lawson, R.A.S. 1976. Pregnancy-specific antigens in the sheep: application to the diagnosis of pregnancy. J. Reprod. Fert. 46: 65–69.CrossRefGoogle Scholar
Challis, J.R.G. 1971. Sharp increase in free circulating oestrogens immediately before parturition in sheep. Nature, Lond. 299: 208.CrossRefGoogle Scholar
Challis, J.R.G., Harrison, F.A. and Heap, R.B. 1973. The metabolic clearance rate, production rate and conversion ratios of oestrone in the sheep. J. Endocr. 58: 435–446.CrossRefGoogle ScholarPubMed
Dobson, H., Midmer, S.E. and Fitzpatrick, R.J. 1975. Relationship between progesterone concetrations in milk and plasma during the bovine oestrous cycle. Vet. Rec. 96: 222–223.CrossRefGoogle Scholar
Donaldson, L.E., Bassett, J.M. and Thorburn, G.D. 1970. Peripheral plasma progesterone concentrations of cows during puberty, oestrous cycles, pregnancy and lactation, and the effects of undernutrition or exogenous oxytocin on progesterone concentration. J. Endocr. 48: 599–614.CrossRefGoogle ScholarPubMed
Edqvist, L.E. and Lamm, A.M. 1971. Progesterone levels in plasma during the oestrous cycle of the sow, measured by rapid competitive protein binding technique. J. Reprod. Fert. 25: 447–448.CrossRefGoogle ScholarPubMed
Foster, D.L., Lemons, J.A., Jaffe, R.B. and Niswender, G.D. 1975. Sequential patterns of circulating luteinizing hormone and follicle-stimulating hormone in female sheep from early postnatal life through the first oestrous cycles. Endocrinology 97: 985–994.CrossRefGoogle Scholar
Gadsby, J.E., Heap, R.B., Henville, A. and Laing, J.A. 1975. A semi-automated technique for the estimation of progesterone in cow's milk and its application to pregnancy diagnosis. J. Physiol. Lond. 242: 3–5P.Google Scholar
Gadsby, J.E., Heap, R.B., Powell, D.G. and Walters, D.E. 1972. Diagnosis of pregnancy and of the number of foetuses in sheep from plasma progesterone concentrations. Vet. Rec. 90: 339–342.CrossRefGoogle ScholarPubMed
Heap, R.B. 1972. Role of hormones in pregnancy. In Reproduction in Mammals. Vol. 3. Hormones in Reproduction, (ed. Austin, C.R. and Short, R.V.), pp. 73–106. Cambridge University Press.Google Scholar
Heap, R.B., Gwyn, M., Laing, J.A. and Walters, D.E. 1973. Pregnancy diagnosis in cows; changes in milk progesterone concentration during the oestrous cycle and pregnancy measured by a rapid radioimmunoassay. J. agrie. Sci., Camb. 81: 151–157.CrossRefGoogle Scholar
Heap, R.B. and Illingworth, D.V. 1974. The maintenance of gestation in the guinea-pig and other hystricomorph rodents: changes in the dynamics of progesterone metabolism and the occurrence of progesterone-binding globulin (PBG). Symp. zool. Soc. Lond. 34: 385–415.Google Scholar
Heap, R.B. and Laing, J.A. 1974. Pregnancy diagnosis in cows; progress report on the use of progestagen concentration in milk. Br. Cattle Breeders Club, Digest No. 29, pp. 27–29.Google Scholar
Heap, R.B., Perry, J.S., Gadsby, J.E. and Burton, R.D. 1976. Endocrine activities of the blastocyst and early embryonic tissue in the pig. Biochem. Trans. 3: 1183–1188.CrossRefGoogle Scholar
Hoffman, B., Hamburger, R., Gunzler, O., Korndorfer, L. and Lohoff, H. 1974. Determination of progesterone in milk applied for pregnancy diagnosis in the cow. Theriogenology 2: 21–28.CrossRefGoogle Scholar
Illingworth, D.V., Heap, R.B. and Perry, J.S. 1970. Changes in the metabolic clearance rate of progesterone in the guinea-pig. J. Endocr. 48: 409–417.CrossRefGoogle ScholarPubMed
Jaffe, B.M. and Behrman, H.R. 1974. Methods of Hormone Radioimmunoassay. Academic Press, New York and London.Google Scholar
Katangole, C.B., Naftolin, F. and Short, R.V. 1971. Relationship between blood levels of luteinizing hormone and testosterone in bulls, and the effects of sexual stimulation. J. Endocr. 50: 457–466.CrossRefGoogle Scholar
Laing, J.A. and Heap, R.B. 1971. The concentration of progesterone in the milk of cows during the reproductive cycle. Br. vet. J. 127: xixxxii.CrossRefGoogle ScholarPubMed
McNatty, K.P., Cashmore, M. and Young, A. 1972. Diurnal variations in plasma cortisol levels in sheep. J. Endocr. 54: 361–362.CrossRefGoogle ScholarPubMed
Paterson, J.Y.F., Bedford, C.A., Harrison, F.A. and Heap, R.B. 1976. Progesterone and 20α-dihydroprogesterone in the sheep: a model of their distribution and metabolism. J. Reprod. Fert. 46: 313–522.CrossRefGoogle Scholar
Paterson, J.Y.F. and Harrison, F.A. 1967. The specific activity of plasma cortisol in sheep during continuous infusion of [l,2-3H2] cortisol, and its relation to the rate of cortisol secretion. J. Endocr. 37: 269–277.CrossRefGoogle Scholar
Perry, J.S., Heap, R.B. and Amoroso, E.C. 1973. Steroid hormone production by pig blastocysts. Nature, Lond. 245: 45–47.CrossRefGoogle ScholarPubMed
Pope, G.S. and Hodgson-Jones, L.S. 1975. Use of plasma progesterone levels in an assessment of embryonic loss in dairy cattle. Vet. Rec. 96: 154.CrossRefGoogle Scholar
Robertson, H.A. 1974. Changes in the concentration of unconjugated oestrone, oestradiol-17α and oestradiol-17β in the maternal plasma of the pregnant cow in relation to the initiation of parturition and lactation. J. Reprod. Fert. 36: 1–7.CrossRefGoogle Scholar
Robertson, H.A. and King, G.J. 1974. Plasma concentrations of progesterone, oestrone, oestradiol-17β and of oestrone sulphate in the pig at implantation, during pregnancy and at parturition. J. Reprod. Fert. 40: 135–141.CrossRefGoogle ScholarPubMed
Robertson, H.A. and Sarda, I.E. 1971. A very early pregnancy test for mammals: its application to the cow, ewe and sow. J. Endocr. 49: 407–419.CrossRefGoogle Scholar
Shevah, Y., Black, W.J.M., Carr, W.R. and Land, R.B. 1975. The effects of nutrition on the reproductive performance of Finn x Dorset ewes. 1. Plasma progesterone and LH concentrations during late pregnancy. J. Reprod. Fert. 45: 283–288.CrossRefGoogle ScholarPubMed
Short, R.V. 1972. Role of hormones in sex cycles. In Reproduction in Mammals. Vol. 3. Hormones in Reproduction, (ed. Austin, C.R. and Short, R.V.), pp. 42–72. Cambridge University Press.Google Scholar
Stabenfeldt, G.H., Osburn, B.I. and Ewing, L.L. 1970. Peripheral plasma progesterone levels in the cow during pregnancy and parturition. Am. J. Physiol. 218: 571–575.CrossRefGoogle ScholarPubMed
Thimonier, J., Pelletier, J. and Land, R.B. 1972. The concentrations of plasma LH in male and female lambs of high and low prolificacy breed types. J. Reprod. Fert. 31: 498–499.CrossRefGoogle ScholarPubMed
Wishart, D.F., Head, V.A. and Hoeth, C.E. 1975. Early pregnancy diagnosis in cattle. Yet. Rec. 96: 34–38.Google ScholarPubMed