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Basic science: (November 2008)

  • R. Sutherland (a1)
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      Basic science: (November 2008)
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1.Alcaraz, J, Xu, R, Mori, H, Nelson, CM, Mroue, R, Spencer, VA, Brownfield, D, Radisky, DC, Bustamante, C, Bissell, MJ. Laminin and biomimetic extracellular elasticity enhance functional differentiation in mammary epithelia. EMBO J 2008; 27: 28292838.
2.Behmoaram, E, Bijian, K, Jie, S, Xu, YJ, Darnel, A, Bismar, TA, Alaoui-Jamali, MA. Focal adhesion kinase-related proline-rich tyrosine kinase 2 and focal adhesion kinase are co-overexpressed in early-stage and invasive ErbB-2-positive breast cancer and cooperate for breast cancer cell tumorigenesis and invasiveness. Am J Pathol 2008; 173: 15401550.
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5.Harbeck, N, Nimmrich, I, Hartmann, A, Ross, JS, Cufer, T, Gruetzmann, R, Kristiansen, G, Paradiso, A, Hartmann, O, Margossian, A, Martens, J, Schwope, I, Lukas, A, Mueller, V, Milde-Langosch, K, Nahrig, J, Foekens, J, Maier, S, Schmitt, M, Lesche, R. Multicenter study using paraffin-embedded tumor tissue testing PITX2 DNA methylation as a marker for outcome prediction in tamoxifen-treated, node-negative breast cancer patients. J Clin Oncol 2008; 26: 50365042.
6.Helczynska, K, Larsson, AM, Mengelbier, LH, Bridges, E, Fredlund, E, Borgquist, S, Landberg, G, Pahlman, S, Jirstrom, K. Hypoxia-Inducible Factor-2 α correlates to distant recurrence and poor outcome in invasive breast cancer. Cancer Res 2008; 68: 92129220.
7.Johansson, H, Gandini, S, Guerrieri-Gonzaga, A, Iodice, S, Ruscica, M, Bonanni, B, Gulisano, M, Magni, P, Formelli, F, Decensi, A. Effect of fenretinide and low-dose tamoxifen on insulin sensitivity in premenopausal women at high risk for breast cancer. Cancer Res 2008; 68: 95129518.
8.Kim, H, Chung, H, Kim, HJ, Lee, JY, Oh, MY, Kim, Y, Kong, G. Id-1 regulates Bcl-2 and Bax expression through p53 and NF-κ B in MCF-7 breast cancer cells. Breast Cancer Res Treat 2008; 112: 287296.
9.Kruschinski, A, Moosmann, A, Poschke, I, Norell, H, Chmielewski, M, Seliger, B, Kiessling, R, Blankenstein, T, Abken, H, Charo, J. Engineering antigen-specific primary human NK cells against HER-2 positive carcinomas. Proc Natl Acad Sci USA 2008; 105: 1748117486.
10.Lee, E, Ma, H, McKean-Cowdin, R, Van Den Berg, D, Bernstein, L, Henderson, BE, Ursin, G. Effect of reproductive factors and oral contraceptives on breast cancer risk in BRCA1/2 mutation carriers and noncarriers: results from a population-based study. Cancer Epidemiol Biomarkers Prev 2008; 17: 31703178.
11.Mathes, RW, Malone, KE, Daling, JR, Davis, S, Lucas, SM, Porter, PL, Li, CI. Migraine in postmenopausal women and the risk of invasive breast cancer. Cancer Epidemiol Biomarkers Prev 2008; 17: 31163122.
12.Nikolsky, Y, Sviridov, E, Yao, J, Dosymbekov, D, Ustyansky, V, Kaznacheev, V, Dezso, Z, Mulvey, L, Macconaill, LE, Winckler, W, Serebryiskaya, T, Nikolskaya, T, Polyak, K. Genome-wide functional synergy between amplified and mutated genes in human breast cancer. Cancer Res 2008; 68: 95329540.
13.Pankratz, VS, Hartmann, LC, Degnim, AC, Vierkant, RA, Ghosh, K, Vachon, CM, Frost, MH, Maloney, SD, Reynolds, C, Boughey, JC. Assessment of the accuracy of the Gail Model in women with atypical hyperplasia. J Clin Oncol 2008; 26: 53745379.
14.Phillips, GDL, Li, GM, Dugger, DL, Crocker, LM, Parsons, KL, Mai, E, Blattler, WA, Lambert, JM, Chari, RVJ, Lutz, RJ, Wong, WLT, Jacobson, FS, Koeppen, H, Schwall, RH, Kenkare-Mitra, SR, Spencer, SD, Sliwkowski, MX. Targeting HER2-positive breast cancer with Trastuzumab-DM1, an antibody–cytotoxic drug conjugate. Cancer Res 2008; 68: 92809290.
15.Plo, I, Laulier, C, Gauthier, L, Lebrun, F, Calvo, F, Lopez, BS. AKT1 inhibits homologous recombination by inducing cytoplasmic retention of BRCA1 and RAD51. Cancer Res 2008; 68: 94049412.
16.Provenzano, PP, Inman, DR, Eliceiri, KW, Beggs, HE, Keely, PJ. Mammary epithelial-specific disruption of focal adhesion kinase retards tumor formation and metastasis in a transgenic mouse model of human breast cancer. Am J Pathol 2008; 173: 15511565.
17.Rottenberg, S, Jaspers, JE, Kersbergen, A, van der Burg, E, Nygren, AOH, Zander, SAL, Derksen, PWB, de Bruin, M, Zevenhoven, J, Lau, A, Boulter, R, Cranston, A, O’Connor, MJ, Martin, NMB, Borst, P, Jonkers, J. High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs. Proc Natl Acad Sci USA 2008; 105: 1707917084.
18.Saunus, JM, French, JD, Edwards, SL, Beveridge, DJ, Hatchell, EC, Wagner, SA, Stein, SR, Davidson, A, Simpson, KJ, Francis, GD, Leedman, PJ, Brown, MA. Posttranscriptional regulation of the breast cancer susceptibility gene BRCA1 by the RNA binding protein HuR. Cancer Res 2008; 68: 94699478.
19.Schwabedissen, H, Tirona, RG, Yip, CS, Ho, RH, Kim, RB. Interplay between the nuclear receptor Pregnane X receptor and the uptake transporter organic anion transporter Polypeptide 1A2 selectively enhances estrogen effects in breast cancer. Cancer Res 2008; 68: 93389347.
20.Sieri, S, Krogh, V, Ferrari, P, Berrino, F, Pala, V, Thiebaut, ACM, Tjonneland, A, Olsen, A, Overvad, K, Jakobsen, MU, Clavel-Chapelon, F, Chajes, V, Boutron-Ruault, MC, Kaaks, R, Linseisen, J, Boeing, H, Nothlings, U, Trichopoulou, A, Naska, A, Lagiou, P, Panico, S, Palli, D, Vineis, P, Tumino, R, Lund, E, Kumle, M, Skeie, G, Gonzalez, CA, Ardanaz, E, Amiano, P, Tormo, MJ, Martinez-Garcia, C, Quiros, JR, Berglund, G, Gullberg, B, Hallmans, G, Lenner, P, Bueno-de-Mesquita, HB, van Duijnhoven, FJB, Peeters, PHM, van Gils, CH, Key, TJ, Crowe, FL, Bingham, S, Khaw, KT, Rinaldi, S, Slimani, N, Jenab, M, Norat, T, Riboli, E. Dietary fat and breast cancer risk in the European prospective investigation into cancer and nutrition. Am J Clin Nutr 2008; 88: 13041312.
21.Sonestedt, E, Borgquist, S, Ericson, U, Gullberg, B, Olsson, H, Adlercreutz, H, Landberg, G, Wirfalt, E. Enterolactone is differently associated with estrogen receptor β-negative and -positive breast cancer in a Swedish nested case–control study. Cancer Epidemiol Biomarkers Prev 2008; 17: 32413251.
22.Su, G, Blaine, SA, Qiao, DH, Friedl, A. Membrane type 1 matrix metalloproteinase-mediated stromal Syndecan-1 shedding stimulates breast carcinoma cell proliferation. Cancer Res 2008; 68: 95589565.
23.Van der Auwera, I, Van Laere, SJ, Van den Bosch, SM, Van den Eynden, GG, Trinh, BX, van Dam, PA, Colpaert, CG, van Engeland, M, Van Marck, EA, Vermeulen, PB, Dirix, LY. Aberrant methylation of the Adenomatous Polyposis Coli (APC) gene promoter is associated with the inflammatory breast cancer phenotype. Br J Cancer 2008; 99: 17351742.
24.Van Laere, S, Beissbarth, T, Van der Auwera, I, Van den Eynden, G, Trinh, XB, Elst, H, Van Hummelen, P, van Dam, P, Van Marck, E, Vermeulen, P, Dirix, L. Relapse-free survival in breast cancer patients is associated with a gene expression signature characteristic for inflammatory breast cancer. Clin Cancer Res 2008; 14: 74527460.
25.Walker, LC, Waddell, N, Ten Haaf, A, Grimmond, S, Spurdle, AB. Use of expression data and the CGEMS genome-wide breast cancer association study to identify genes that may modify risk in BRCA1/2 mutation carriers. Breast Cancer Res Treat 2008; 112: 229236.
26.Wayne, S, Neuhouser, ML, Ulrich, CM, Koprowski, C, Wiggins, C, Baumgartner, KB, Bernstein, L, Baumgartner, RN, Gilliland, F, McTiernan, A, Ballard-Barbash, R. Association between alcohol intake and serum sex hormones and peptides differs by tamoxifen use in breast cancer survivors. Cancer Epidemiol Biomarkers Prev 2008; 17: 32243232.
27.Wolf, I, Levanon-Cohen, S, Bose, S, Ligumsky, H, Sredni, B, Kanety, H, Kuro-o, M, Karlan, B, Kaufman, B, Koeffler, HP, Rubinek, T. Klotho: a tumor suppressor and a modulator of the IGF-1 and FGF pathways in human breast cancer. Oncogene 2008; 27: 70947105.
28.Zhang, HJ, Liu, G, Dziubinski, M, Yang, ZQ, Ethier, SP, Wu, GJ. Comprehensive analysis of oncogenic effects of PIK3CA mutations in human mammary epithelial cells. Breast Cancer Res Treat 2008; 112: 217227.
29.Zhao, JJ, Lin, JH, Yang, H, Kong, W, He, LL, Ma, X, Coppola, D, Cheng, JQ. MicroRNA-221/222 negatively regulates estrogen receptor α and is associated with tamoxifen resistance in breast cancer. J Biol Chem 2008; 283: 3107931086.

Basic science: (November 2008)

  • R. Sutherland (a1)


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