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Output hypothesis: Peering into the black box

  • Wade H. Berrettini (a1)


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Akiskal, H. S., McKinney, W. T. Jr, (1973) Depressive disorders: Toward a unified hypothesis. Science 182:2029. ]HSA]
Angst, J. B., Woggon, J., Schoepf, J. (1977) The treatment of depression with 5-hydroxytryptophan versus imipramine. Archiv für Psychiatric und Nervenkrankheiten 224:175-86. ]MHA]
Anisman, H., Kokkinidis, L., Sklar, L. S. (1981) Contribution of neurochemical change to stress-induced behavioral deficits. In: Theory in psychopharmacology, vol. 1, ed. Cooper, S. J., pp. 65102. Academic Press. ]HA]
Anismais, H., Remington, C., Sklar, L. S. (1979) Effects of inescapable shock on subsequent escape performance: Catecholaminergic and cholinergic mediation of response initiation and maintenance. Psychopharmacology 61:107–24. ]HA]
Anisman, H., Zacharko, R. M. (1982) Depression: The predisposing influence of stress. Behavioral and Brain Sciences 5:89137. ]taEAS]
Antelman, S. M. & Chiodo, L. A. (1981) Dopamine autoreceptor subsensitivity: A mechanism common to the treatment of depression and the induction of amphetamine psychosis. Biological Psychiatry 16:717–27. ]HA]
Antelman, S. M., Chiodo, L. A. & DeGiovanni, L. A. (1982) Antidepressants and dopamine autoreceptors: Implications for both a novel means of treating depression and understanding bipolar illness. In: Typical and atypical antidepressants: Molecular mechanisms, ed. Costa, E. & Racagni, C., pp. 121–32. Raven Press. ]HA]
Aprison, M. H. & Hingtgen, J. N. (1981) Hypersensitive serotonergic receptors: A new hypothesis for one subgroup of unipolar depression derived from an animal model. In: Serotonin: Current aspects of neurochemistry and function, ed. Haber, B., Cabay, S., Alivisatos, S. & Issidorides, M., pp. 627–56. Plenum Press. ]MHA]
Aprison, M. H. & Hingtgen, J. N. (1983) New depression theory: Predictions based on neurochemical/behavioral data. Transactions of the American Society of Neurochemistry 14:201. ]MHA]
Aprison, M. H., Hingtgen, J. N., Nagayama, H. (1982) Testing a new theory of depression with an animal model: Neurochemical-behavioral evidence for postsynaptic serotonergic receptor involvement. In: New vistas in depression, ed. Langer, S. A., Takahashi, H., Segawa, T. & Briley, M., pp. 171–78. Pergamon Press. ]MHA]
Aprison, M. H., Takahashi, R. & Tachiki, K. (1978) Hypersensitivity serotonergic receptors involved in clinical depression: A theory. In: Ncuropharmacology and behavior, ed. Haber, B. & Aprison, M. H., pp. 2353. Plenum Press. ]MHA]
Askew, E. W. & Hecker, A. L. (1976) Adipose tissue cell size and lipolysis in the rat: Response to exercise intensity and food restriction. Journal of Nutrition 106:1351–60. ]taEAS]
Askew, E. W., Hecker, A. L. & Wise, W. R. Jr, (1977) Dietary carnitine and adipose tissue turnover rate in exercise trained rats. Journal of Nutrition 107:132–42. ]taEAS]
Askew, E. W., Huston, R. L., Plopper, C. G. & Hecker, A. L. (1975) Adipose tissue cellularity and lipolysis. Response to exercise and cortisol treatment. Journal of Clinical Incestigation 56:521–29. ]taEAS]
Aston-Jones, G. & Bloom, F. E. (1981) Norepinephrine containing locus ceruleus neurons in behaving rats exhibit promsounced responses to nonnoxious stimuli. Journal of Neuroscience 1:887–99. ]US]
Aston-Jones, G., Foote, S. L. & Bloom, F. E. (1982) Low doses of ethanol disrupt sensory responses of brain noradrenergic neurons. Nature 296:857–60. ]RMC]
Aulakh, C. S., Cohen, R. M., Pradhan, S. N. & Murphy, D. L. (in press) Self-stimulation responses are altered following long-term but not short- term antidepressant treatmeist. Brain Research. ]RMC]
Baldessarini, R. J. (1975) The basis for amine hypotheses in affective disorders: A critical evaluation. Archives of General Psychiatry 32:1087–93. ]AF, taEAS]
Bancrjee, S. P., Kung, L. R., Riggi, S. J. & Chanda, S. K. (1977) Development of β-adrenergic receptor subsensitivity by antidepressants. Nature 268:455–56. ]taEAS, JV]
Bancrjee, S. P., Sharma, V. K., Kung, L. S. & Chanda, S. K. (1978) Amphetamine induces β-adrenergic receptor supersensitivity. Nature 271:380–81. ]taEAS]
Barka, T. & Burke, G. T. (1977) Secretory behavior of hypertrophic and hyperplastic salivary gland. Histochemical Journal 9:453–66. ]taEAS]
Baudry, M., Martres, M. P. & Schwartz, J. C. (1976) Modulation in the sensitivity of oradrencrgic receptors in the CNS studied by the responsiveness of the cyclic AMP system. Brain Research 116:111–24. ]taEAS]
Belenky, G. L., Holaday, J. W. (1981) Repeated electroconvulsive shock (EGS) and morphine tolerance: Demonstration of cross-sensitivity in the rat. Life Sciences 29:553–63. ]taEAS]
Belmaker, R. H. (1981) Receptors, adenylate cyclase, depression and lithium. Biological Psychiatry 16:333–50. ]taEAS]
Bergstrom, D. A., Kellar, K. J. (1979) Effect of electroconvulsive shock on monoaminergic receptor binding sites in rat brain. Nature 278:464–66. ]JV]
Bertin, R. & Portet, R. (1976) Effects of lipolytic and antilipolytic drugs on metabolism of adenosine 3': 5'-monophosphate in brown adipose tissue of cold acclimated rats. European Journal of Biochemistry 67:177–83. ]taEAS]
Besse, J. C. & Bass, A. D. (1966) Potentiation by hydrocortisone of responses to catecholamines in vascular smooth muscle. Journal of Pharmacology and Experimental Therapeutics 154:224–38. ]taEAS]
Bevegard, B. S. & Shepherd, J. T. (1967) Regulation of the circulation during exercise in man. Physiological Reviews 47:178213. ]taEAS]
Bhatia, S. P. & Davies, H. J. (1975) Evaluation of tolerance after continuous and prolonged oral administration of salbutamol to asthmatic patients. British Journal of Clinical Pharmacology 2:436–66. ]taEAS]
Bjorklund, A., Katzman, R., Stenevi, U. & West, K. (1971) Development and growth of axonal sprouts from NA and 5-hydroxytryptamine neurons in the rat spinal cord. Brain Research 31:2133. ]taEAS]
Bjorklund, A. & Stenevi, U. (1971) Growth of central catecholamine neurons into smooth muscle grafts in the rat mesencephalon. Brain Research 31:120. ]taEAS]
Blosser, J. C. (1983) β-Adrenergic receptor activation increases acetylcholine receptor number in cultured skeletal muscle myotubes. Journal of Neurochemistry 40:1144–49. ]rEAS]
Bodnar, R. J., Kelly, D. D., Brutus, M. & Glusman, M. (1980) Stress- induced analgesia: Neural and hormonal determinants. Neuroscience and Biobehavioral Reviews 4:87100. ]taEAS]
Brenner, G. M. & WuIf, R. G. (1981) Adrenergic beta receptors mediating submandibular salivary gland hypertrophy in the rat. Journal of Pharmacology and Experimental Therapeutics 218:608–12. ]taEAS]
British Medical Council (1965) Clinical trial of treatment of depressive illness. British Medical Journal 1:881. ]AF]
Brunello, N., Barbaccia, M. L., Chuang, D. M. & Costa, E. (1982) Down regulation of β-adrenergic receptors following injections of desmethylimipramine: Permissive role of serotonergic axons. Neuropharmacology 21:1145–49. ]rEAS]
Bukowiecki, L., Follea, N., Vallieres, J. & LeBlanc, J. (1978) β-Adrenergic receptors in brown-adipose tissue. Characterization and alterations during acclimation of rats to cold. European Journal of Biochemistry 92:189–96. ]taEAS]
Burke, G. T. & Barka, T. (1978) Beta-adrenergic receptors and adenylate cyclase in hypertrophic and hyperplastic rat salivary glands. Biochimica et Biophysica Acta 539:5461. ]taEAS]
Bylund, D. B. & Snyder, S. H. (1976) Beta adrenergic receptor bindimsg in membrane preparations from mammaliam brain. Molecular Pharmacology 12:568–80. ]taEAS]
Campbell, I. C., McKernan, R. M. (1982) Central and peripheral changes in α-adrenoceptors in the rat in response to chronic antidepressant drug administration. In: New vistas in depression, ed. Langer, S. Z., Takashi, R., Segawa, T. & M., Briley, pp. 153160. Pergamon Press. ]JV]
Campos, H. A. & Parr, J. J. (1968) Enlargement of the guinea pig salivary gland caused by catecholamines or tooth amputation. European Journal of Pharmacology 2:371–76. ]taEAS]
Carroll, B. J. (1977) Psychiatric disorders and steroids. In: Neuroregulators and psychiatric disorders, ed. Usdin, E., Hamburg, D. A. & Barchas, J. D., pp. 276–82. Oxford University Press. ]taEAS]
Carroll, B. J., Curtis, G. C., Mendels, J. (1976) Cerebrospinal fluid and plasma free cortisol concentrations in depression. Psychological Medicine 6:235–44. ]taEAS]
Carroll, B. J., Feinberg, M., Greden, J. F., Tarika, J., Albala, A. A., Haskett, R. F., James, N.M., Kronfol, Z., Lohr, N., Steiner, M., deVigne, J. P. Vigne, J. P., Young, E. (1981) A specific laboratory test for the diagnosis of melancholia. Archives of General Psychiatry 38:1522. ]taEAS]
Cedarbaum, J. M. & Ághajanian, G. K. (1976) Noradrenergic neurons on the locus coeruleus: Inhibition by epinephrine and activation by the α-antagonist piperoxane. Brain Research 112:413–19. ]KAR]
Cedarbaum, J. M., Ághajanian, G. K. (1977) Catecholamine receptors on locus coeruleus neurons. Pharmacological characterization. European Journal of Pharmacology 44:375–85. ]taEAS]
Cerrito, F. & Raiteri, M. (1981) Supersensitivity of central noradrenergic presynaptic autoreceptors following chronic treatment with the antidepressant mianserin. European Journal of Pharmacology 70:425–26. ]taEAS, JV]
Charney, D. S., Hafstad, K. M., Ciddings, S. & Landis, D. H. (1982) Adrenergic receptor sensitivity in depression: Effects of clonidinc in depressed patients and healthy subjects. Archives of General Psychiatry 39:290–94. ]CBS]
Charney, D. S., Heninger, G. R. & Sternberg, D. E. (1983) Alpha-2 adrenergic receptor sensitivity and the mechanism of action of antidepressant therapy. British Journal of Psychiatry 142:265–75. ]CBS]
Charney, D. S., Heninger, G. R., sternberg, D. E., Hafstad, K. M., Giddings, S., Landis, D. H. (1982) Adrenergic receptor sensitivity in depression. Archices of General Psychiatry 39:290–94. ]HAD]
Charney, D. S., Heninger, G. R., Sternberg, D. E., Redmond, D. E., Leckman, J. F., Mass, J. W. & Roth, R. H. (1981) Presynaptic adrenergic receptor sensitivity in depression. Archives of General Psychiatry 38:1334–40. ]RJK]
Charney, D. C., Menkes, D. B. & Heninger, G. R. (1981) Receptor sensitivity and the mechanism of action of antidepressant treatment: Implications for the etiology and therapy of depression. Archices of General Psychiatry 38:1160–80. ]RAD, LJS, CBS, taEAS]
Chatelain, P., Robberecht, P., De, Neef P., Camus, J. C. & Cristophe, J. (1982) Early decrease in secretin-, glucagon-, and isoproterenolstimulated cardiac adenylate cyclase activity in rats treated with isoproterenol. Biochemical Pharmacology 31:347–52. ]taEAS]
Chiodo, L. A. & Antelman, S. M. (1980) Repeated tricyclics induce a progressive dopamnine autoreceptor subsensitivity independent of daily drug treatment. Nature 287:451–54. ]HA]
Ciaranello, R. D., Barchas, R. E., Byers, G. S., Stemmle, D. W. & Barchas, J. D. (1969) Enzymatic synthesis of adrenaline in mammalian brain. Nature 221:368–69. ]KAR]
Clements-Jewery, S. (1978) The development of cortical β-adrenoceptor subsensitivity in the rat by chronic treatment with trazodone, doxepin and mianserine. Neuropharmacology 17:779–81. ]taEAS]
Cohen, J., Aroesty, J. M. & Rosenfeld, M. G. (1966) Determinants of thyroxine induced cardiac hypertrophy in mice. Circulation Research 18:388–97. ]taEAS]
Cohen, R.M., Aulakh, C. S., Campbell, I. C. & Murphy, D. L. (1982) Functional subsensitivity of α2-adrenoceptors accompanies reductions in yohimbine binding after clorgyline treatment. European Journal of Pharmacology 81:145–48. ]RMC]
Cohen, R. M. & Campbell, I. C. (in press) Receptor adaptation in animal models: A state change approach to psychiatric illness. In: Neurobiology of the mood disorders, ed. Ballenger, J. C. & Post, R. M.. Williams and Wilkins. ]RMC]
Cohen, R. M., Campbell, I. C., Cohen, M. R., Torda, T., Pickar, D., Siever, L. J. & Murphy, D. L. (1980) Presynaptic noradrenergic regulation during depression and antidepressant drug treatment. Psychiatry Research 3:93105. ]RMC, CBS]
Cohen, R. M., Campbell, I. C., Dauphin, M., Tallman, J. F., Murphy, D. L. (1982) Changes in α- and β-receptor densities in rat brain as a result of treatment with monoamine oxidase inhibiting antidepresssnts. Neuropharmacology 21:293–98. ]CBS]
Cohen, R. M., Ebstein, R. P., Daly, J. W. & Murphy, D. L. (1982) Chronic effects of a monoamine-oxidase inhibiting antidepressant: Decrease in functional alpha-adrenergic antoreceptors precede the decrease in norepinephrine stimnulated cyclic AMP systems in rat brain. Journal of Neuroscience 2:1588–95. ]RMC]
Colucci, W. S., Alexander, W., Williams, G. H., Rude, R. E., Holman, B. L., Konstam, M. A., Wynne, J., Mudge, G. H. & Braunwald, E. (1981) Decreased lymphocyte beta-adrenergic receptor density in patients with heart failure and tolerance to the beta-adrenergic agonist pirbuterol. New England Journal of Medicine 305:185–90. ]taEAS]
Cooper, B. R. & Butz, R. F. (1982) Behavioral and biochemical effects of chronic infusion of the novel antidepressant, bupropion, in rats. Society for Neuroscience Abstracts 8:465. ]taEAS]
Coppen, A., Whybrow, P. C., Noguera, R., Maggs, R. & Prange, A. J. Jr, (1972) The comparative antidepressant value of L-tryptophan and imipramine with and without attempted potentiation by liothyronine. Archives of General Psychiatry 26:234–41. ]taEAS]
Cotman, C. W. & Nieto-Sampedro, M. (1982) Brain function, synapse removal and plasticity. Annual Review of Psychology 33:371401. ]taEAS]
Crews, F. T., Paul, S. M. & Goodwin, F. K. (1981) Acceleration of beta- receptor desensitization in combined administration of antidepressants and phenoxybenzamine. Nature 290:787–89. ]WBE, CBS]
Crews, F. T., Smith, C. B. (1978) Presyisaptic alpha-receptor subsensitivity after long-term antidepressant treatment. Science 202:322–24. ]CBS]
Crews, F. T., Smith, C. B. (1980) Potentiation of responses to adrenergic nerve stimulation in isolated rat atria during chronic tricyclic antidepressant administration. Journal of Pharmacology and Experimental Therapeutics 215:143–49. ]CBS]
Cutilletta, A. F., Thilenius, O. G. & Areilla, R. A. (1972) Adenyl cyclase activity in experimental myocardial hypertrophy. American journal of Cardiology 29:258. ]taEAS]
Daly, J. W., Padgett, W., Nimitkitpaisan, Y., Creveling, C. R., Cantacuzene, D. & Kirk, K. L. (1980) Fluoronorepinephrines: Specific agonists for the activation of alpha and beta adrenergic-sensitive cyclic AMP-generating systems in brain slices. Journal of Pharmacology and Experimental Therapeutics 212:382–89. ]taEAS]
Deakin, J. F. W., Owen, F., Cross, A. J. & Dashwood, M. J. (1981) Studies on possible mechanisms of action of electroconvulsive therapy: Effects of repeated electrically induced seizures on rat brain receptors for monoamines and other neurotransmitters. Psychopharmacology 73:345–49. ]taEAS]
DeMontigny, C. & Aghajanian, G. K. (1978) Tricyclic antidepressants: Long term treatment increases responsivity of rat forebrain neurons to serotonin. Science 202:1303–6. ]tarEAS]
DeMontigny, C., Grunberg, F., Mayer, A. & Deschenes, J. P. (1981) Lithium induces rapid relief of depression in tricyclic antidepressant drug non-responders. British Journal of Psychiatry 138:252–56. ]rEAS]
Denber, H. C. B. (1975) Pharmacotherapy of depression. In: Psychopharmacological treatment: Theory and practice, ed. Denber, H. C. B., pp. 121–34. Marcel Dekker. ]taEAS]
Dengler, J. H., Spiegel, H. E. & Titus, E. O. (1961) The effect of drugs on the uptake of isotopic norepinephrine by cat tissues. Nature 191:816–17. ]taEAS]
DeVellis, J. & Kukea, G. (1973) Regulation of glial cell functions by hormones and ions: A review. Texas Reports on Biology & Medicine 31:271–93. ]taEAS]
Dismukes, R. K., Daly, J. W. (1976) Adaptive responses of brain cyclic AMP generating systems to alterations in synaptic input. Journal of Cyclic Nucleotide Research 2:321–36. ]taEAS]
Dohin, G. L., Pennington, S. N. & Brakat, H. (1976) Effect of exercise training on adenyl cyclase and phosphodiesterase in skeletal muscle, heart and liver. Biochemical Medicine 16:138–42. ]taEAS]
Evans, J. P. M., Grahame-Smith, D. G., Green, A. R. & Tordoff, A. F. C. (1976) Electroconvulsive shock increases the behavioral responses of rats to brain 5-hydroxytryptamine accumulation and central nervous system stimulant drugs. British Journal of Pharmacology 56:193–99. ]taEAS]
Evonuk, E. & Hannon, J. P. (1963) Cardiovascular function and norepinephrine thermogenesis in cold-acclimated rats. American Journal of Physiology 204:888–94. ]taEAS]
Exton, J. H., Friedman, N., Wonge, H. A., Brineaux, J. P., Corbin, J. D. & Park, C. R. (1972) Interactions of glucocorticoids with glucagon and epinephrine in the control of gluconeogenesis and glycogenolysis in liver and of lipolysis in adipose tissue. Journal of Biological Chemistry 247:3579–88. ]taEAS]
Fain, J. N. (1977) Cyclic nucleotides in adipose tissue. In: Cyclic– 3',5'- nucleotides: Mechanism of action, ed. Crammer, H. & Schultz, J., pp. 205–28. John Wiley and Sons. ]taEAS]
Feighner, J. P., King, L. J., Schuckit, M. A., Croughan, J. & Briscoe, W. (1972) Hormonal potentiation of imipramine and ECT in primary depression. American journal of Psychiatry 128:1230–38. ]taEAS]
Felten, D. L., Hallman, H. & Jonsson, G. (1982) Evidence for a neurotropic role of noradrenaline neurons in the postnatal development of rat cerebral cortex. Journal of Neurocytology 11:119–35. ]taEAS]
Ferris, R. M., Maxwell, R. A., Cooper, B. R. & Soroko, F. E. (1982) Neurochemical and neuropharmacological investigations into the mechanisms of action of bupropion. HCI– A new atypical antidepressant agent. In: Typical and atypical antidepressants: Molecular mechanisms, ed. Costa, E. & Racagni, G., pp. 277–86. Raven Press. ]taEAS]
Fibiger, H. C., Phillips, A. G. (1981) Increased intracranial self-stimulation its rats after long-term administration of desipramine. Science 214:683–84. ]HA]
Fink, M., Klein, D. F. &, Kramer, J. C. (1968) Clinical efficacy of chlorpromazine-procyclidine combination, imipramine and placebo in depressive disorders. Psychopharmacologia 7:2736. ]taEAS]
Formgren, H. (1976) The therapeutic value of oral long-term treatment with terbutaline (Bricanyl) in asthma. Scandinavian Journal of Respiratory Diseases 57:321–25. ]taEAS]
Foster, D. O. & Frydman, M. L. (1978) Nonshivering thermogenesis. II. Measurements of blood flow with microspheres point to brown adipose tissue as the dominant site of the calorigenesis induced by noradrenaline. Canadian Journal of Physiology and Pharmacology 56:110–22. ]taEAS]
Frazer, A. (1951) Tricyclic antidepressants– basic considerations. In: Neuropharmacology of central nervous system and behavior disorders, ed. Palmer, G. C., pp. 7391. John Wiley and Sons. ]AF]
Frazer, A., Hess, M. E., Mendels, J., Gable, B., Kunkel, E. & Bender, A. (1978) Influence of acute and chronic treatment with desmethylimipramine on catecholamine effects in the rat. Journal of Pharmacology and Experimental Therapeutics 206:311–19. ]taEAS]
Fregly, M. F., Nelson, E. L., Resch, G. E., Field, F. P. & Lutherer, L. O. (1975) Reduced beta adrenergic responsiveness in hypothyroid rats. American Journal of Physiology 229:916–24. ]taEAS]
Friedli, C., Chinet, A. & Girardier, L. (1978) Comparative measurements of in vitro thermogenesis of brown adipose tissue from control and cold adapted rats. Experientia 32 (supp.):259–66. ]taEAS]
Friedman, E. & Dallob, A. (1979) Enhanced serotonin receptor activity after chronic treatment with imipramine or amitriptyline. Communications in Psychopharmacology 3:8992. ]tarEAS]
Fuller, R. W. (1982) Pharmacology of brain epinephrine neurons. Annual Review of Pharmacology and Toxicology 22:3155. ]KAR]
Fuxe, K., Bolme, P., Agnati, L. F., Jonsson, G., Andersson, K., Kohler, C. & Hokfelt, T. (1980) On the role of central adrenaline neurons in central cardiovascular regulation. In: Central adrenaline neurons, ed. Fuxe, K., Goldstein, M., Hokfelt, B. & Hokfelt, T., pp. 161–82. Pergamon Press. ]KAR]
Fuxe, K., Ogren, S. O., Agnati, L. F., Benfenati, F., Fredholm, B., Andersson, K., Zini, I. & Enroth, P. (1983) Chronic antidepressant treatment and central 5-HT synapses. Neuropharmacology 22:389400. ]MHA]
Garcia-Sevilla, J. A., Hollingsworth, P. J. & Smith, C. B. (1981) Platelet α2-Adrenoreceptors on human platelets: Selective labelling by ]3H]clonidine and ]3H]yohimbine and competitive inhibition by antidepressant drugs. European Journal of Pharmacology 74:329–41. ]CBS]
Garcia-Sevilla, J. A., Zis, A. P., Hollingsworth, P. J, Creden, J. F., Smith, C. B. (1981) Plateletα2-adrenergic receptors in major depressive disorder. Archives of General Psychiatry 38:1327–33.]Ri K, CBS]
Garzon, J. & DelRio, J. Rio, J. (1981) Hyperactivity induced us rats by long-term isolation: Further studies on a new animal model for the detection of antidepressants. European Journal of Pharmacology 74:287–94. ]taEAS]
Gerry, J. I., Sourisseau, G., Swissa, A. & Evonuk, E. (1981) Chonotropic responses in rats given repeated injections of isoproterenol, norepinephrine or chronically exercised. (abstract) Federation Proceedings 40:464. ]taEAS]
Glass, I. B., Checkly, S. A., Shur, E. & Dawlimsgs, S. (1982) The effect of desipramine upon central adrenergic function depressed patients. British Journal of Psychiatry 41:372–76. ]RMC]
Glaubiger, G. & Letkowitz, R. J. (1977) Elevated beta-adrenergic receptor number after chronic propranolol treatment. Biochemistry and Biophysics Research Communications 78:720–25. ]taEAS]
Goldberg, M. R., Curatolo, P. W., Tung, C. S. & Robertson, D. (1982) Caffeine down-regulates β-adrenoreceptors in rat forebrain. Neuroscience Letters 31:4752. ]taEAS]
Górka, Z. & Zacny, E. (1981) The effect of single and chronic administration of imipramine on clonidine-induced hypothermia in the rat. Life Sciences 28:2847–54. ]RMC, JV]
Crahame-Smith, D. G., Green, A. R. & Costain, D. W. (1978) The mechanism of the antidepressant effect of ECT. Lancet 1:2 5457. ]taEAS]
Gram, L. F. (1977) Plasma level monitoring of tricyclic antidepressant therapy. Clinical Pharmacokinetics 2:237–51. ]taEAS]
Gray, J. A. (1977) Drug effects on fear and frustration: Possible limbic site of action of minor tranquilizers. In: Handbook of psychopharmacology, vol. 8: Drugs, neurotransmitters, and behavior, ed. Iversems, L. L., Iversen, S. D. & Snyder, S. H.. Plenum Press. ]RAD]
Greden, J. F., Gardner, R., King, D., Grunhaus, L., Carroll, B. J. & Kronfol, Z. (1983) Dexamethasone suppression tests in antidepressant treatment of melancholia. Archives of General Psychiatry 40:493500. ]rEAS]
Green, A. R., Costain, D. W. & Deakin, J. F. (1980) Enhanced 5-hydroxytryptamine and dopamine-mediated behavioural responses following convulsions. III. The effects of monoamine antagonists and synthesis inhibitors on the ability of electroconvulsive shock to enhance responses. Neuropharmacology 19:907–24. ]taEAS]
Green, A. R. & Deakin, J. F. W. (1980) Brain noradrenaline depletion prevents ECS induced enhancement of serotonin and dopamine mediated behaviours. Nature 285:232–33. ]taEAS]
Greenblatt, D. J., Shader, R. I. (1972) On the psychopharmacology of betaadrenergic blockade. Current Therapeutic Research 14:615-25. ]taEAS, JV]
Griswold, R. L. & Gray, I. (1957) Conditioning of rats to trauma by electroconvulsive shock. American Journal of Physiology 189:504–8. ]taEAS]
Grossman, W., Robin, N.J., Johnson, L. W., Brooks, H., Selenkow, H. A. & Dexter, L. (1971) Effects of beta blockade on the peripheral manifestations of thyrotoxicosis. Annals of Internal Medicine 74:875–81. ]taEAS]
Hall, H., Ross, S. B., Ogren, S. O. (1982) Effect of zimelidine on various transmitter systems in the brain. In: Typical and atypical antidepressants: Molecular mechanisms, ed. Costa, E. & Racagni, G., pp. 321–25. Raven Press. ]taEAS]
Hallberg, H., Almgren, O. & Svensson, T. H. (1981) Increased brain serotonergic and noradrenergic activity after repeated systemic administration of the beta-2 adrenoceptor agonist salbutamol, a putative antidepressant drug. Psychopharmacology 73:201–4. ]taEAS]
Harri, M. N. E. (1978) Metabolic and cardiovascular responses to prolonged noradrenaline load and their antagonism by beta blockade in the rat. Acta Physiologica Scandinavica 104:402–14. ]taEAS]
Harri, M. N. E. & Narvola, I. (1979) Physical training under the influence of beta blockade in rats: Effect on adrenergic responses. European Journal of Applied Physiology 41:199210. ]taEAS]
Heal, D. J., Akagi, H., Bowdler, J. M. & Green, A. R. (1981) Repeated electroconvulsive shock attenuates clonidine-induced hypoactivity in rodents. European Journal of Pharmacology 75:231–37. ]RMC, JV]
Heal, D. J. & Green, A. R. (1978) Repeated electroconvulsive shock increases the behavioral responses of rats to injections of both dopamine and dibutyryl cyclic AMP into the nucleus accumbens. Neuropharmacology 17:1085–87. ]taEAS]
Herman, J. P., Guillonneau, D., Dantzer, R., Scatton, B., Semerdjian-Rouquier, L. & LeMoal, M. (1982) Differential effects of inescapable footshocks and of stimuli previously paired with inescapable footshocks on dopamine turnover in cortical and limbic areas of the rat. Life Sciences 30:2207–14. ]HA]
Hertz, L. (in press) Astrocytes. In: Handbook of neurochemistry. ed. Lajtha, A.. 2d ed.Plenum Press. ]taEAS]
Hertz, L., Mukerji, S. & Richardson, J. S. (1981) Down regulation of betaadrenergic activity in astroglia by chronic treatment with an antidepressant drug. European Journal of Pharmacology 72:267–68. ]taEAS]
Herve, D., Tassin, J. P., Barthelemy, C., Blanc, G., Levielle, S. & Glowinski, J. (1979) Difference in the reactivity of the mesocortical dopaminergic neurons to stress in the BALB/c and C57BL/6 mice. Life Sciences 25:1659–64. ]HA]
Hess, M. E., Prostran, M., Carricato, A. M., Locke, C. L, Brzozowski, C., Sills, M. & Viscuse, D. (1982) Interaction between thyroxine and tricyclic antidepressant antidepressant drugs on cardiac neurotransmitter receptors. Journal of Cardiocascular Pharmacology 4:856-62. ]rEAS]
Heydorn, W. E., Brunswick, D. J. & Frazer, A. (1982) Effect of treatment of rats with antidepressants on melatonin concentrations in the pineal gland and serum. Journal of Pharmacology and Experimental Therapeutics 222:534–43. ]AF, tarEAS]
Heydorn, W. E., Fraser, A. & Weiss, B. (1981) Electrical stimulation of sympathetic nerves increases the concentration of cyclic AMP in rat pineal gland. Proceedings of the National Academy of Sciences 78:7176–79. ]taEAS]
Himms-Hagen, J. (1972) Effects of catecholamines on metabolism. In: Catecholamines: Handbook of experimental pharmacology, vol. 33, ed. Blaschko, H. & Muscholl, E., pp. 363462. Springer-Verlag. ]taEAS]
Hingtgen, J. N., Hendrie, H. C. & Aprison, M. H. (1982) Acute and chronic effects of a new antidepressant, trazodone, on an animal model of depression. Society for Neuroscience Abstracts 8:101. ]MHA]
Holgate, S. T., Baldwin, C. J. & Tattersfield, A. E. (1977) Beta-adrenergic agonist resistance in normal human airways. Lancet 2:375–77. ]taEAS]
Hong, J. S., Gillin, J. C., Yang, H. Y. T. & Costa, E. (1979) Repeated elcctroconvulsivc shocks and the brain content of endorphins. Brain Research 177:273–78. ]taEAS]
Huang, Y. H. (1979a) Chronic desipramine treatment increases activity at noradrenergic postsynaptic cells. Life Sciences 25:709–16. ]HA, LJS, tarEAS]
Huang, Y. H. (1979b) Net effect of acute administration of desipramine on the locus coeruleus-hippocampal system. Life Sciences 25:739–46. ]US, taEAS]
Huang, Y. H., Mass, J. W. & Hu, G. H. (1980) The time course of noradrenergic pre- and postsynaptic activity during chronic desipraminc treatment. European Journal of Pharmacology 68:4147. ]AF, YHH, rES]
Irwin, J., Bowers, W., Zacharko, R. M., Anisman, H. (1982) Stress-induced alterations of norepinephrine: Cross-stressor sensitization. Society for Neuroscience Abstracts 8:359. ]HA]
Iversen, L. L. (1965) The inhibition of noradrtenaline uptake by drugs. Adcances in Drug Research 2:523. ]taEAS]
Janowsky, A., Okada, F., Manier, D. H., Applegate, C. D., Sulser, F. & Steranka, L. R. (1982) Role of serotonergic input in the regulation of theβ-adrenergic receptor coupled adenylate cyclase system. Science 218:900901. ]tarEAS]
Jansky, L. & Hart, J. S. (1968) Cardiac output and organ blood flow in warm and cold acclimated rats exposed to cold. Canadian Journal of Physiology & Pharmacology 46:653–59. ]taEAS]
Jenne, J. W., Chick, T. W., Strickland, R. D. & Wall, F. J. (1977) Subsensitivity of beta responses during therapy with a long-acting beta-2 preparation. Journal of Allergy and Clinical Immunology 59:383–90. ]taEAS]
Jesberger, J. A. & Richardson, S. S. (1981) Actions of amitriptyline in an animal model of depression. (abstract) Transactions of the American Society of Neurochemistry 11:276. ]taEAS]
Jimerson, D. C., Insel, T. R. & Kopin, I. J. (1983) Increased plasma MHPC in dexamethasone-resistant depressed patients. Archices of General Psychiatry 40:173–76. ]rEAS]
Katz, M. M., Koslow, S.H., Mass, J. W., Bowden, C. L., Croughan, J., Kocsis, J. & Redmond, D. E. Jr, (submitted for publication) The timing and specificity of drug effects in unipolar and biopolar depressions. ]AF]
Katz, R. J., Carroll, B. J. (1977) Brain stimulation reward: Evidence for an adrenergic contribution in the rat. Neuroscience Letters 5:227–31. ]KAR]
Katz, R. J., Carroll, B. J. (1978) Inhibition of phenylethanolamine-N-methy transferase and brain stimulated reward. Psychopharmacology 57:3942. ]RJK]
Kebabian, J. W., Zatz, M., Romcro, J. A. & Axelrod, J. (1975) Rapid changes in rat pineal β-adrenergic receptor: Alterations in 1-]3H] alprenolol binding and adenylate cyclase. Proceedings of the National Academy of Sciences 72:3735–39. ]LJS taEAS]
Kellar, K., Cascio, C. S., Bergstrom, D. A., Butler, J. A. & Iadarola, P. (1981) Electroconvulsive shock and reserpine: Effects on β-adrenergic receptors in rat brain. Journal of Neurochemistry 37:830–36. ]tarEAS]
Kellar, K. J., Cascio, C. S., Butler, J. A. & Kurtzke, R. N. (1981) Differential effects of electroconvulsive shock and antidepressant drugs on serotonin-2 receptors in rat brain. European Journal of Pharmacology 69:515–18. ]taEAS]
Kendal, D. A., Stancel, G. M. & Enna, S. J. (1982) The influence of sex hormones on antidepressant-induced alterations in neurotransmitter receptor binding. Journal of Neuroscience 2:354–60. \taEAS]
Korf, J., Sevens, J. B. & Postema, F. (1979) Cyclic AMP in the rat cerebral cortex after stimulation of the locus coermileus: Decrease by antidepressant drugs. European Journal of Pharmacology 59:2330. ]taEAS]
Kraeuchi, K., Gentsch, C. & Feer, H. (1981) Individually reared rats: Alteration in noradrenergic brain functions. Journal of Neural Transmission 50:103–12. ]taEAS]
Kuroshima, A. & Yahata, T. (1979) Thermogenic responses of brown adipocytes to noradrenaline and glucagon in heat-acclimated and cold-acclimated rats. Japanese Journal of Physiology 29:683–90. ]taEAS]
Lambert, P. L., Harrell, E. H. & Emmett-Oglesby, M. W. (1980) Attenuation of response deficits by electroconvulsive shock. Physiological Psychology 8:107–11. ]taEAS]
Lands, A. M., Arnold, A., McAuliff, J. P., Ludwena, F. P. & Brown, T. G. (1967) Differentiation of receptor systems activated by sympathomimetic amines. Nature 214:597–98. ]WBE]
Langer, S. Z., Briley, M. S. & Raisman, R. (1980) Regulation of neurotransmission through presynaptic receptors and other mechanisms: Possible clinical relevance and therapeutic potential. In: Receptors for neurotransmitters and peptides, ed. Pepau, G., Kuhar, M. J. & Enna, S. J., pp. 203–12. Raven Press. ]taEAS]
Langer, S. Z., Cavero, I. & Massingham, R. (1980) Recent developments in noradrenergic neurotransmission and its relevance to the mechanism of action of certain antihypertensive agents. hypertension 2:372–82. ]WBE]
LeBlanc, J., Vallieres, J. & Vachon, C. (1972) Beta-receptor sensitization by repeated injection of isoproterenol and by cold adaptation. American Journal of Physiology 222:1043–46. ]taEAS]
LeBlanc, J. & Villemaire, A. (1970) Thyroxine and noradrenaline on noradrenaline sensitivity cold resistance and brown fat. American Journal of Physiology 281:1742–45. ]taEAS]
Leerubier, Y., Puech, A. J., Frances, H., Jouvent, R., Widlocher, D. & Simon, P. (1981) Beta-adrenergic stimulation and antidepressant activity. Acta Psychiatrica Scandinacica 63 (supp. 290):173–81. ]taEAS]
Leibowitz, S. F. (1970) Reciprocal hunger relating circuits involving alpha-and-beta-adrenergic receptors located, respectively, in the ventro medial and lateral hypothalamus. Proceedings of the National Academy of Sciences 67:1063–70. ]RJK]
Leibowitz, S. F. (1975) Catecholamine mechanisms of the lateral hypothalamus; Their role in the mediation of amphetamine anorexia. Brain Research 98:529–45. ]AF]
Leshner, A. I., Remler, H., Biegon, A. & Samuel, D. (1979) Desmethylimipramine (DMI) counteracts learned helplessness in rats. Psychopharmacology 66:207–8. ]taEAS]
Linnoila, M., Karoum, F., Calil, H. M., Kopin, I. J. & Potter, W. Z. (1982) Alteration of norepinephrine metabolism with desipramine and zimelidine in depressed patients. Archices of General Psychiatry 39:1025–28. ]taEAS]
Liu, S. J. & Wang, R. I. H. (1981) Increased sensitivity of the central nervous system to morphine analgesia by amitriptyline in naive and morphinetolerant rats. Biochemical Pharmacology 30:2103–9. ]taEAS]
Lucki, I. & Frazer, A. (1982) Prevention of the serotonin syndrome in rats by repeated administration of monoamine oxidase inhibitors but not tricyclic antidepressants. Psychopharmacology 77:205–11. ]rEAS]
Maas, J. W., Dekirmenjian, H. & Fawcett, J. A. (1972) Catecholamine metabolism, depressive illness and drug response. Archives of General Psychiatry 26:252–62. ]rEAS]
McCarthy, K. D. & DeVellis, J. (1979) The regulation of adenosine 3':5'–cyclic monophosphate accumulation in glia by alpha-adrenergic agonists. Life Sciences 24:639–50. ]taEAS]
McMillen, B., Warnack, W., German, D. C. & Shore, P. A. (1980) Effect of chronic desipramine treatment on rat brain noradrenergic responses to alpha-adrenergic drugs. European Journal of Pharmacolocy 61:239–46. ]LJS. CBS, taEAS]
McNeil, C. N., Shaw, P. K. & Dock, D. S. (1982) Substitution of atenolol for propranolol in a case of propranolol-related depressiois. American Journal of Psychiatry 139:1187–88. ]rEAS]
Maeda, T., Tohyama, M. & Shimizu, N. (1974) Modification of postnatal development of neocortex in rat brain with experimental deprivation of locus coeruleus. Brain Research 70:515–20. ]taEAS]
Maj, J., Górka, Z., Melzacka, M., Rawtów, A. & Pilc, A. (1983) Chronic treatment with imipramine: Further functional evidence for the enhanced noradrenergic transmission in flexor reflex activity. Naunyn-Schmiedebergs Archices of Pharmacology 322:256–60. ]LJS]
Maj, J., Mogilnicka, E. & Klimek, V. (1979) The effect of repeated administration of antidepressant drugs on the responsiveness of rats to catecholamine agonists. Journal of Neural Transmission 44:221–35. ]taKAS, JV]
Maj, J., Mogilnicka, E., Klimek, V. & Kordecka-Magiera, A. (1981) Chronic treatment with antidepressants: Potentiation of clonidine-induced aggression in mice via noradrenergic mechanism. Journal of Neural Transmission 52:189–97. ]JV]
Maj, J., Mogilnicka, E. & Kordecka, A. (1979) Chronic treatment with antidepressant drugs: Potentiation of apomorphine-induced aggressive behaviour in rats. Neuroscience Letters 13:337–41. ]JV]
Maj, J., Mogilnicka, E. & Kordecka-Magiera, A. (1980) Effect of chronic administration of antidepressant drugs on aggressive behavior induced by clonidine in mice. Pharmacology, Biochemistry and Behavior 13:153–54. ]JV]
Makman, M. H. (1971) Properties of adenylate cyclase of lymphoid cells. Proceedings of the National Academy of Sciences 68:885–89. ]taEAS]
Maletsky, B. M. (1978) Seizure duration and clinical effect in electroconvulsivc therapy. Comprehensice Psychiatry 19:541–50. ]taEAS]
Mendels, J. & Frazer, A. (1974) Brain biogenic amine depletion and mood. Archives of General Psychiatry 30:447–51. ]AF, taEAS]
Menkes, D. B. & Aghajanian, G. K. (1981) α1-Adrenoceptor-mediated responses in the lateral geniculate nucleus are enhanced by chronic antidepressant treatment. European Journal of Pharmacology 74:2736. ]LJS. taEAS, JV]
Mickey, J., Tate, H. & Lefkowitz, R. J. (1975) Subsensitivity of adenylate cyclase and decreased beta-adrenergic receptor binding after chronic exposure to (-) isoprotereisol in vitro. Journal of Biological Chemistry 250:5727–29. ]taEAS]
Minneman, K. P., Dibner, M. D., Wolfe, B. B. & Molinoff, P. B. (1979) β1- andβ2-adrenergic receptors in rat cerebral cortex are independently regulated. Science 204:866–68. ]WBE]
Minneman, K. P., Hegstrand, L. R. & Molinoff, P. B. (1979) Comparison of beta adrenergic subtypes in mammalian tissues, Journal of Pharmacology and Experimental Therapeutics 211:502–8. ]WBE]
Minneman, K. P., Pittman, R. N. & Molinoff, P. B. (1981) β-Adrenergic receptor subtypes: Properties, distribution, and regulation. Annual Review ofNeuroscience 4:419–61. ]KAR]
Mishra, R., Janowsky, A. & Sulser, F. (1980) Action of mianserine and zimelidine on the norepinephrine receptor coupled adenylate cyclasc system in brain: Subsensitivity without reduction in beta-adrenergic receptor binding. Neuropharmnacology 19:983–87. ]taEAS]
Mobley, P. L., Sanders-Bush, E., Smith, H. E. & Sulser, F. (1979) Modification of the noradrenergic cyclic AMP generating system in the rat limbic forebrain by amphetamine: Role of its hydroxylated metabolites. Naunyn-Schmiedebergs Archives of Pharmacology 306:267–73. ]taEAS]
Mobley, P. L. & Sulser, F. (1979) Norepinephrine stimulated cyclic AMP accumulation in rat limbic forebrain: Partial mediation by a subpopulation of receptors with neitherα norβ characteristics. European Journal of Pharmacology 60:221–27. ]taEAS]
Modigh, K. (1975) Electroconvulsive shock and postsynaptic catecholamine effects: Increased psychomotor stimulant actioms of apomorphimie amid clonidine in reserpine pretreated mice by repeated ECS. Journal of Neural Transmission 36:1932. ]taEAS, JV]
Mogilnicka, E. (1982) The effects of acute and repeated treatment with salbutamol. a β-adrenoceptor agonist, on clonidine-induced hypoactivity in rats. Journal of Neural Transmission 53:117–26. ]taEAS]
Mogilnicka, E. & Klimek, V. (1979a) Effect of chronic administration of antidepressant drugs on the noradrenaline disappearance induced by FLA-63 in the rat brain. Polish Journal of Pharmacology and Pharmacy 31:139–47. ]taEAS]
Mogilnicka, E. & Klimek, V. (1979b) Mianserin, danitracen and amitriptyline withdrawal increases the behavioral response of rats to L-5-HTP. Journal of Pharmacy and Pharmacology 31:704–5. ]taEAS]
Moore, R. L., Riedy, M. J. & Gollnick, P. D. (1982) Effect of training on β-adrenergic receptor number in rat heart. Journal of Applied Physiology 52:1133–37. ]taEAS]
Mueller, A. L., Hoffer, B. J. & Dunwiddie, T. V. (1981) Noradrenergic responses in rat hippocampus: Evideisce for mediation by alpha and beta receptors in the in vitro slice. Brain Research 214:113–26. ]taEAS]
Muirhead, M. & Himms-Hagen, J. (1971) Changes in amount and properties of adenyl cyclase in brown adipose tissue during acclimation of rats to cold. Canadian Journal of Biochemistry 49:802–10. ]taEAS]
Murphy, D. L., Campbell, I. & Costa, J. L. (1978) Current status of the indoleamine hypothesis of affective disorders. In: Psychopharmacology: A generation of progress, ed. Lipton, M. A., DiMascio, A. & Killam, K. F., pp. 1235–48. Pergamon Press. ]HA]
Nagayama, H., Hingtgen, J. N. & Aprison, M. H. (1980) Pre- and postsynaptic serotonergic manipulations in an animal model of depression. Pharmacology, Biochemistry and Behavior 13:575579. ]MHA]
Nagayama, H., Hingtgen, J. N. & Aprison, M. H. (1981) Postsynaptic action by four antidepressive drugs in an animal model of depression. Pharmacology, Biochemistry and Behacior 15:125–30. ]MHA]
Nahorski, S. R., Howlett, D. R., Redgrave, P. (1979) Loss of betaadrenergic binding sites in rat striatum following kainic acid lesions. European Journal of Pharmacology 60:249–52. ]taEAS]
Nemeroff, C. B. & Evans, D. L. (1983) Concurrent use of antidepressants and propranolol: Case report and theoretical considerations. Biological Psychiatry 18:237–41. ]rEAS]
Nielsen, M. & Braestrup, C. (1977) Chronic treatment with desipramine causes a sustained decrease of 3,4-dihydroxyphenylglycol-sulfate and total 3-methoxy-4-hydroxyphenylglycol in the rat brain. Naunyn-Schmiedebergs Archives of Pharmacology 300:8792. ]taEAS]
Nomura, S., Watanabe, M., Ukei, N. & Nakazawa, T. (1981) Stress and β-adrenergic receptor binding in the rat's brain. Brain Research 224:199203. ]taEAS]
Nomura, Y., Kajiyama, H. & Oki, K. (1982) Influence of repeated administration of desmethylimipramine on beta adrenergic and muscarinic cholinergic receptors and 45Ca+ + binding to sarcoplasmic reticulum in the rat heart. Journal of Pharmacology and Experimental Therapeutics 223:834–40. [rEAS]
Nomura, Y., Kajiyama, H. & Segawa, T. (1982) Alteration in sensitivity to isoproterenol and acetylcholine in the rat heart after repeated administration of isoproterenol. Journal of Pharmnacology and Experimental Therapeutics 220:411–16. ]taEAS]
Novak-Hofer, I., Malnoe, A. & Stein, E. A. (1980) Regulation of a presynaptic adenylate cyclase from bovine cerebellum by beta-adrenergic receptors. Biochimica and Biophysica Acta 599:167–74. [WBE]
Ogren, S. O., Fuxe, K., Agnati, L. F., Gustafsson, J. A., Jonsson, G. & Holm, A. C. (1979) Reevaluation of the indoleamine hypothesis of depression: Evidence for a reduction of functional activity of central 5-HT systems by antidepressant drugs. Journal of Neural Transmission 46:85103. [MHA]
Olpe, H. R. & Schellenberg, A. (1980) Reduced sensitivity of neurons to noradrenaline after chronic treatment with antidepressant drugs. European Journal of Pharmacology 63:713. [AF, taEAS]
Olpe, H. R. & Schellenberg, A. (1981) The sensitivity of cortical neurons to serotonin. Effect of chronic treatment with antidepressants, serotonin-uptake inhibitors and monoamine-oxidase blocking drugs. Journal of Neural Transmission 51:233–44. [rEAS]
Ostman, I. & Nyback, H. (1976) Adaptive changes in central and peripheral noradrenergic neurons in rats following chronic exercise. Neuroscience 1:4147. [rEAS]
Ostman-Smith, I. (1976) Prevention of exercise-induced hypertrophy in rats by chemical sympathectomy. Neuroscience 1:497507. [taEAS]
Ostman-Smith, I. (1979) Adaptive changes in the sympathetic nervous system and some effector organs of the rat following long term exercise or cold acclimation and the role of cardiac sympathetic nerves in the genesis of compensatory cardiac hypertrophy. Acta Physiologica Scandinavica (supp. 477):1118. [taEAS]
Oswald, I., Brezinova, V. & Dunleavy, D. L. F. (1973) On the slowness of action of tricyclic antidepressant drugs. British Journal of Psychiatry 120:673–77. [taEAS]
Palmer, G. C., Wagner, H. R. & Putnam, R. W. (1976) Neuronal localization of the enhanced adenylate cyclase responsiveness to catecholamine in the rat cerebral cortex following reserpine injections. Neuropharmacology 15:695702. [taEAS]
Pandey, G. N., Heinze, W. J., Brown, B. D. & Davis, J. M. (1979) Electroconvulsive shock treatment decreasesβ-adrenergic receptor sensitivity in rat brain. Nature 280:234–35. [JV]
Paykel, E. S., Price, J. S., Gillan, R. U., Palmai, C. & Chesser, E. S. (1968) A comparative trial of imipramine and chlorpromazine in depressed patients. British Journal of Psychiatry 114:1281–87. [taEAS]
Peroutka, S. J., Snyder, S. H. (1980) Long term antidepressant treatment decreases spiroperidol-labeled serotonin receptor binding. Science 210:8890. [rEAS]
Peroutka, S. J., Snyder, S. H. (1983) Multiple serotonin receptors and their physiological significance. Federation Proceedings 42:213–17. [MHA]
Perry, E. K., Marshall, E. F., Blessed, G., Tomlinson, B. E. & Perry, R. H. (1983) Decreased imipramine binding in the brains of patients with depressive illness. British Journal of Psychiatry 142:188–92. [HSA]
Petrie, W. M., Maffucci, H. J., Woosley, R. L. (1982) Propranolol and depression. American Journal of Psychiatry 139:9293. [WBE, taEAS]
Pettigrew, J. D., Kasamatsu, T. (1978) Local perfusion of noradrenaline maintains visual cortical plasticity. Nature 271:761–63. [taEAS]
Petty, E., Sherman, D. (1979) Reversal of learned helplessness by imipramine. Communications in Psychopharmacology 3:371–73. [taEAS]
Phillis, J. W. (1977) The role of cyclic nucleotides in the CNS. Canadian Journal of Neurological Sciences 4:151–95. [taEAS]
Pilc, A. & Vetulani, J. (1982a) Attenuation by chronic imipramine treatment of [3H]clonidine binding to cortical membranes and of clonidine-induced hypothermia: The influence of central chemosympathectomy. Brain Research 238:499504. ]
Pilc, A., Vetulani, J. (1982b) Depression by chronic electroconvulsive treatment of clonidine hypothermia and [3H]clonidine binding to rat cortical membranes. European Journal of Pharmacology 80:109113. [CBS, JV]
Platt, J. E., Stone, E. A. (1982) Chronic restraint stress elicits a positive antidepressant response on the forced swim test. European Journal of Pharmacology 82:179–81. [rEAS]
Platt, J. E., Trullas, R., Slucky, A. V. & Stone, E. A. (1983) Interrelationships between adaptation to stress and antidepressant treatment. (abstract) Society for Neuroscience Abstracts, in press. [rEAS]
Porsolt, R. D., Anton, G., Blavet, N. & Jalfre, M. (1978) Behavioral despair in rats: A new model sensitive to antidepressant treatments. European Journal of Pharmacology 4:379–81. [rEAS]
Post, R. M., Goodwin, F. K. (1978) Approaches to brain amines in psychiatric patients: A reevaluation of cerebrospinal fluid studies. In: Handbook of psychopharmacology, vol. 13, ed. Iversen, L. L., Iversen, S. D. & Snyder, S. D.. Plenum Press. [HA]
Post, R. M., Jimerson, D. C., Reus, V. I., Goodwin, F. K., Silberman, E. & Bunney, W. E. (1979) Dopaminergic agents in affective illness: Studies with pirebidil, amphetamine and pimozide. In: Catecholamnines: Basic and clinical Frontiers, vol. 2, ed. Usdin, E., Kopin, I. J. & Barchas, J.. Pergamon Press. [HA]
Praag, H. M. van (1978) Amine hypotheses of affective disorder. In: Handbook of psycho pharmacology, vol. 13, ed. Iversen, L. L., Iversen, S. D. & Snyder, S. H.. Plenum Press. [HA]
Praag, H. M. van (1979) Central serotonin: Its relation to depression vulnerability and depression prophylasix. In: Biological psychiatry today, ed. Objols, E., Ballus, C., Monclus, E. Gonzales & Pujol, J., pp. 485–98. Elsevier. [MHA]
Praag, H. M. van (1981) Management of depression with serotonin precursors. Biological Psychiatry 16:291310. [MHA, rEAS]
Praag, H. M. van (1983) In search of the mode of action of antidepressants. Neuropharmacology 22:433–40. [MHA]
Prange, A. J. Jr (1972) In discussion Feighner, J. P., King, L. J., Schuckit, M. A., Croughan, J. & Briscoe, W., Hormonal potentiation of imipramine and ECT in primary depression. American journal of Psychiatry 128:1230–38. [taEAS]
Prange, A. J. Jr & Loosen, P. T. (1982) Hormone therapy in depressive diseases. In: Typical and atypical antidepressants: Molecular mechanisms, ed. Costa, E. & Racagni, G., pp. 289–96. Raven Press. [taEAS]
Prange, A. J. Jr, Wilson, J. C., Rabon, A. M. & Lipton, M. A. (1969) Enhancement of imipramine antidepressant activity by thyroid hormone. American Journal of Psychiatry 126:457–69. [taEAS]
Prasad, K. N. (1975) Differentiation of neuroblastoma cells in culture. Biological Reciew 50:129–66. [taEA5]
Prowse, J., Noreika, L., Gerhardt, S., Leibnian, J. (1981) Selective attenuation of intracranial self stimulation by the beta-2 agonist, salbutamol. (abstract) Federation Proceedings 40(3):293. [RJK]
Przegalinski, E., Kordecka-Magiera, A., Mogilnicka, E. & Maj, J. (1981) Chronic treatment with some atypical antidepressants increases the brain level of 3-methoxy-4-hydroxyphenylglycol (M HPC) in rats. Psychopharmacology 74:187–90. [taEAS]
Rabinowitz, M. & Zak, R. (1972) Biochensical and cellular changes in cardiac hypertrophy. Annual Reuiew of Medicine 23:245–62. [taEAS]
Racagni, G., Mocchetti, I., Renna, G. & Cuomo, V. (1982) In vivo studies on central noradrenergic synaptic mechanisms after acute and chronic antidepressant treatment: Biochemical and behavioral comparison. journal of Pharmacology and Experimental Therapeutics 223:227-34. [CBS]
Raskin, A., Schulterbrandt, J. C., Reatig, N. & MeKeon, J. J. (1970) Differential response to chlorpromazine, imipramine and placebo. Archives of General Psychiatry 23:164–73. [taEAS]
Redmond, D. E. (1977) Alterations in the function of the nucleus locus coeruleus: A possible model for studies in anxiety. Animal models in psychiatry and ncurology, ed. Hanin, L. & Usdin, E., pp. 293304. Pergamon Press. [LJS]
Reisine, T., Johnson, R., Wiech, N., Ursillo, R. & Yamamura, H. I. (1982) Rapid desensitization of central beta-receptors and tip-regulation of alpha2-receptors following antidepressant treatnsent. In: Typical and atypical antidepressants: Molecular mechanisms, ed. Costa, E. & Racagni, G., pp. 6367. Raven Press. [CBS]
Reisine, T. D., U'Prichard, D. C., Wiech, N. L., Ursillo, R. C. & Yamamura, H. I. (1980) Effects of combined administration of amphetamine and iprindole on brain adrenergic receptors. Brain Research 188:587–92. [tarEAS]
Riess, W., Dubey, E. W., Funfgeld, P., Imhof, P., Hurzeler, H., Matussek, N., Rajagopalan, T. G., Raschdorf, F. & Schmid, K. (1975) The pharmocokinetic properties of maprotihine (Lsidiomil) in man, journal of International Medical Research 3 (supp. 2):1641. [taEAS]
Risch, S. C., Huey, L. Y. & Janowsky, D. S. (1979) Plasma levels of tricyclic antidepressants and clinical efficacy: Review of the literature, part II. journal of Clinical Psychiatry 40:5869. [taEAS]
Roberts, D. C. S. & Bloom, F. E. (1981) Adrenal steroid-induced changes in beta-adrenergic receptor binding in rat hippocampus. European Journal of Pharmacology 74:3742. [IaEAS]
Robinson, S. E., Mobley, P. L., Smith, H. E. & Sulser, F. (1978) Structural and steric requirements for β-pheimethylamines as agonists of the noradrenergic cyclic AMP generating system in the rat limbic forebrain. Naunyn-Schmiedebergs Archices of Pharmacology 303:175–80. [taEAS]
Roisen, F. J. & Murphy, R. A. (1973) Neurite development in vitro. II. The role of microfilament and microtubules in dubtyrl adenosine 3′,5′-cyclic monophosphate and nerve-growth factor stimulated maturation, journal of Neurobiology 4:397412. [taEAS]
Roth, K. A. & Katz, R. J. (1981) Further studies on a novel animal model of depression: Therapeutic effects of a tricyclic antidepressant. Neuroscience and Biobehavioral Reviews 5:253–58. [taEAS]
Roth, K. A., Katz, R. J., Sibel, M., Mefford, I. N., Barchas, J. D. & Carroll, B. J. (1981) Central epinergic inhibition of corticosterone release in rat. Life Sciences 28:2389–94. [KAR]
Roth, K. A., Mefford, I. N. & Barchas, J. D. (1982) Epinephrine, norepinephrine, dopamine, and serotonin: Differential effects of acute and chronic stress on regional brain amines. Brain Research 239:417–24. [KAR]
Sabol, S. L. & Nirenberg, M. (1979) Regulation of adenylate cyclase of neuroblastoma x glioma hybrid cells by α-adrenergic receptors. Journal of Biological Chemistry 254:1913–20. [taEAS]
Sachar, E. J., Hellman, L., Fukushima, D. K. & Gallagher, T. F. (1970) Cortisol production in depressive illness. Archives of General Psychiatry 23:289–98. [taEAS]
Sachar, E. J., Hellman, L., Roffwarg, H., Halpern, F. S., Fukushima, D. K. & Gallagher, T. F. (1973) Disrupted 24-hour patterns of cortisol secretion in psychotic depression. Archives of General Psychiatry 28:1924. [taEAS]
Sarai, K., Frazer, A., Brunswick, D. & Mendels, J. (1978) Desmethylimipramine-induced decrease in beta-adrenergic receptor binding sites in rat cerebral cortex. Biochemical Pharmacology 27:2179–81. [AF]
Sauter, A. M., Baba, Y., Stone, E. A. & Goldstein, M. (1978) Effect of stress and of phenylethanolamine-N-methyltransferase inhibition on central norepinephrine and epinephrine levels. Brain Research 144:415–19. [KAR]
Schildkraut, J. J. (1965) The catecholamitie hypothesis of affective disorders: A review of supporting evidence. American journal of Psychiatry 122:509–22. [taEAS]
Schildkraut, J. J. (1969) Neuropharmacology and the affective disorders. Second part. New England journal of Medicine 281:248–55. [taEAS]
Schildkraut, J. J. (1978) Current status of the catecholamine hypothesis of affective disorders. In: Psychopharmacology: A generation of progress, ed. Lipton, M. A., DiMascio, A. & Killam, K. E., pp. 1223–34. Raven Press. [taEAS]
Schildkraut, J. J. & Kety, S. S. (1967) Biogenic amines and emotion. Science 156:2129. [RAD, YHH, taEAS, JV]
Schneyer, C. A. & Hall, D. H. (1967) Autonomic regulation of the immature and adult rat parotid gland. In: Secretory mechanisms of salivary glands, eds. Schneyer, C. A. & Schneyer, L. H., pp. 155–77. Academic Press. [taEAS]
Schoffelmeer, A. & Mulder, A. H. (1982) 3H-noradrenaline and 3-H-5- hydroxytryptamine release from rat brain slices and its presynaptic alphaadrenergic modulation after long-term desipramine pretreatment. NauynSchmiedebergs Archives of Pharmacology 318:173–80. [RMC]
Schultz, J. (1976) Psychoactive drug effects on a system which generates cyclic AMP in brain. Nature 261:417–18. [taEAS]
Schultz, J. E., Siggins, G. R., Schocker, F. W., Turck, M. & Bloom, F. E. (1981) Effects of prolonged treatment with lithium and tricyclic antidepressants on discharge frequency, norepinephrine responses and beta receptor binding in rat cerebellum: Electrophysiological and biochemical comparison. journal of Pharmacology and Experimental Therapeutics 216:2838. [AF, taEAS]
Schultz, J. E., Siggins, G. R., Turck, M. & Bloom, P. E. (1982) Electrophysiological and biochemical comparison of the acute and chronic effects of lithium and tricyclic antidepressants. Advances in Biochemical Psychopharmacology 31:347–58. [LJS]
Schweitzer, J. W., Schwartz, R. & Friedhoff, A. J. (1979) Intact presynaptic terminals required for beta-adrenergic receptor regulation by desipramine. journal of Neurochemistry 33:377–79. [taEAS]
Scott, J. A. & Crews, F. T. (1983) Rapid decrease in rat brain beta adreisergic receptor binding during combined antidepressant alpha-2 antagonist treatment. Journal of Pharmacology and Experimental Therapeutics 224:640–46. [CBS]
Scuvee-Moreau, J. J. & Svensson, T. H. (1982) Sensitivity in vivo of central α2- and opiate receptors after chronic treatment with various antidepressants. Journal of Neural Transmission 54:5163. [CBS]
Segal, D. S., Kuczenski, R. & Mandell, A. J. (1974) Theoretical implications of drug-induced adaptive regulation for a biogenic amine hypothesis of affective disorder. Biological Psychiatry 9:147159. [rEAS]
Segal, M. & Bloom, F. E. (1974) The action of norepinephrine in the rat hippocaunpus I. lontophoretic studies. Brain Research 72:7997. [YHH]
Segawa, T., Mizuta, T. & Uehara, M. (1982) Role of central serotonergic system as related to pathogenesis of depression: Effect of antidepressants on rat central serotonergic activity. In: New vistas in depression, ed. Langer, S. Z., Takahashi, R., Segawa, T. & Briley, M., pp. 319. Pergamon Press. [MEIA]
Sellinger-Barnette, M. M., Mendels, J. & Frazer, A. (1980) The effect of psychoactive drugs on beta-adrenergic receptor binding sites in rat brain. Neuropharmacology 19:447–54. [taEAS]
Selye, H., Veilleux, R. & Cantin, T. (1961) Excessive stimulation of salivary gland growth by isoproterenol. Science 133:4445. [taEAS]
Sengupta, K., Tong, K. J. & Allen, D. O. (1981) Relationship among isoproterenol, cyclic AMP, cyclic AMP-dependent protein kinase and lipolysis in perfused fat cells. Journal of Pharmacology and Experimental Therapeutics 218:128–33. [taEAS]
Serra, G., Argiolas, A., Fadda, F. & Gessa, G. L. (1980) Hyposensitivity of dopamine “autorcccptors” induced by chronic administration of tricyclic antidepressants. Pharmacological Research Communications 12:619–24. [taEAS]
Serra, G., Argiolas, A., Fadda, F., Melis, M. R. & Gessa, G. L. (1981) Repeated electroconvulsive shock prevents the sedative effect of small doses of apomorphine. Psychopharmacology 73:94196. [taEAS]
Serra, G., Melis, M. R., Argiolas, A., Fadda, F. & Gessa, G. L. (1981) REM sleep deprivation induces subsensitivity of dopamine receptors mediating sedation in rats. European Journal of Pharmacology 72:131–35. [taEAS]
Sethy, V. H. & Harris, D. G. (1981) Effect of norepinephrine uptake blocker on β-adrenergic receptors of the rat cerebral cortex. European journal of Pharmacology 75:5356. [taEAS]
Shepherd, M. (1965) Clinical trial of the treatment of depressive illness. Report to the Medical Research Council by its Clinical Psychiatry Committee. British Medical journal 1:881–86. [taEAS]
Shepherd, R. E., Noble, E. G., Klug, G. A. & Gollnick, P. D. (1981) Lipolysis and cAMP accumulation in adipocytes in response to physical training. Journal of Applied Physiology 50:143–48. [tarEAS]
Sheppard, J. R. & Prasad, K. N. (1973) Cyclic AMP levels and the morphological differentiation of mouse neuroblastoma cells. Life Sciences 12:431–39. [taEAS]
Shopsin, B., Friedman, E. & Cershon, S. (1976) Parschloroplscnylalaninc reversal of tranylcypromine effects in depressed patients. Archives of General Psychiatry 33:811–19. [rEAS]
Shopsin, B., Wilk, S., Sathananthan, C., Cershon, S. & Davis, K. (1974) Catecholamines and affective disorders revised: A critical assessment. Journal of Nervous and Mental Diseases 158:369–83. [taEAS]
Siever, L. J., Cohen, R. M. & Murphy, D. L. (1981) Antidepressants may induce α2-adrenergic autoreceptor desensitization in man. American journal of Psychiatry 138:681–82. [RMC, JV]
Siever, L. J., Uhde, T. W. & Murphy, D. L. (1982) Possible subsensitization of alpha2-adrenergic receptors by chronic monoamine oxidase inhibitor treatment in psychiatric patients. Psychiatry Research 6:293302. [US, CBS]
Siever, L. J., Uhde, T. W., Potter, W. Z. & Murphy, D. L. (1983) Norepinephrine in the affective disorders: Receptor assessment strategies. In: Norepinephrine: Clinical aspects, ed. Lake, C. R. & Ziegler, M. G.. Williams & Wilkins Co. [LJS]
Siever, L. J., Uhde, T. W., Silberman, E. K., Jimerson, D. C., Aloi, J. A., Post, R. M. & Murphy, D. L. (1982) Growth hormone response to clonidine as a probe of noradrenergic receptor responsiveness in affective disorder patients and controls. Psychiatry Research 6:171–83. [CBS]
Siggins, G. R. & Schultz, J. E. (1979) Chronic treatment with lithium or despramine alters discharge frequency and norepinephrine responsiveness of cerebellar Purkinje cells. Proceedings of the National Academy of Sciences 76:5987–91. [taEAS]
Smith, C. B. & Carcia-Sevilla, J. A. (1982) Alpha2 adrenoreceptors in endogenous depression. Advances in the Biosciences 40:99106. [CBS, rES]
Smith, C. B., Garcia-Sevilla, J. A. & Hollingsworth, P. J. (1981) Alpha2 adrenoceptors in rat brain are decreased after long-term tricyclic antidepressant drug treatment. Brain Research 210:413–18. [CBS, taEAS, JV].
Smith, C. B., Hollingsworth, P. J., Garcia-Sevilla, J. A. & Zis, A. P. (1983) Platelet alpha2 adrenoreceptors are decreased in number after antidepressant therapy. Progress in Neuro-Psychopharmacology and Biological Psychiatry 7, in press. [CBS]
Smith, R. E. & Horwitz, B. A. (1969) Brown fat and thermnogenesis. Physiological Reviews 49:330425. [taEAS]
Sokoloff, L. (1981) Relationships among local functional activity, energy, metabolism and blood flow in the central nervous system. Federation Proceedings 40:2311–16. [RMC]
Spyraki, C. & Fibiger, H. C. (1980) Functional evidence for subsensitivity of noradrenergic alpha2 receptors after chronic desipramine treatment. Life Sciences 27:1863–67. [JV]
Spyraki, C. (1981) Behavioral evidence for supersensitivity of postsynaptic dopamine receptors in the mesolimbic system after chronic administration of desipramine. European journal of Pharmacology 74:195206. [rEAS]
Stanford, S. C. & Nutt, D. J. (1982) Comparison of the effects of repeated electroconvulsive shock on α2- and β-adrenoceptors in different regions of rat brain. Neuroscience 7:1753–57. [CBS]
Stanley, M., Virgilio, J. & Gershon, S. (1982) Tritiated imipramine binding sites are decreased in the frontal cortex of suicides. Science 216:1337–39. [HSA]
Stanton, H. C., Brenner, G. & Mayfield, E. D. (1969) Studies on isoproterenol-induced cardiomegaly in rats. American Heart Journal 77:7280. [taEAS]
Starkman, M. N., Schteingart, D. E. & Schork, M. A. (1981) Depressed mood and other psychiatric manifestations of Cushing's Syndrome: Relationship to hormone levels. Psychosomatic Medicine 43:318. [taEAS]
Stein, L., Wise, C. D. & Belluzi, J. D. (1977) Neuropharmacology of reward and punishment. In: handbook of psychopharmacology, vol. 8, pp. 2549. Plenum Press. [LJS]
Stone, E. A. (1975) Effects of stress on sulfated glycol metabolites of brain norepinephrine. Life Sciences 16:1725–30. [taEAS]
Stone, E. A. (1978) Effect of stress on norepinephrine-stimulated accumulation of cyclic AMP in rat brain slices. Pharmacology Biochemistry and Brhavior 8:585–91. [taEAS]
Stone, E. A. (1979 a) Reduction by stress of norepinephrine-stimulated accumulation of cyclic AMP in rat cerebral cortex. Journal of Neurochemistry 32:1335–37. [taEAS]
Stone, E. A. (1979 b) Subsensitivity to norepinephrine as a link between adaptation to stress and antidepressant therapy: An hypothesis. Research Communications in Psychology, Psychiatry and Behavior 4:241–55. [taEAS]
Stone, E. A. (1982) Noradrenergic function during stress and depression: An alternative view. Behavioral and Brain Sciences 5:122. [taEAS]
Stone, E. A. & McCarty, R. (1983) Adaptation to stress: Tyrosine hydroxylase activity and catecholamine release. Neurosciences and Biobehavioral Reviews 7:2934. [rEAS]
Stone, E. A. & Platt, J. E. (1982) Brain adrenergic receptors and resistance to stress. Brain Research 237:405–14. [taEAS]
Stone, E. A., Platt, J. E., Trullas, R. & Slucky, A. V. (1983) Comparison of effects of stress and antidepressants on noradrenergic receptor function in rat brain. (abstract) Society for Neuroscience Abstracts, in press. [rEAS]
Su, Y. F., Cubeddu, L. & Perkins, J. P. (1976) Regulation of adenosine 3′: 5′- monophosphate content of human astrocytoma cells: Desensitization to catecholamines and prostaglandins. Journal of Cyclic Nucleotide Research 2:257–70. [taEAS]
Su, Y. F., Harden, T. K. & Perkins, J. P. (1980) Catecholamine-speciflc desensitization of adenylate cyclase. Journal of Biological Chemistry 255:7410–19. [IaEAS]
Sugrue, M. G. (1980 a) Changes in rat brain monoamine turnover following chronic antidepressant administration. Life Sciences 26:423–29. [taEAS]
Sugrue, M. F. (1980 b) The inability of chronic mainserin to block central α2-adrenoceptors. European Journal of Pharmacology 68:377–80. [taEAS]
Sugrue, M. F. (1981) Effects of acutely and chronically administered antidepressants on the clonidine-induced decrease in rat brain 3-methoxy-4-hydroxyphenylethylene glycol sulphate content. Life Sciences 28:377–84. [taEAS]
Sugrue, M. F. (1982 a) Effect of chronic antidepressants on rat brain α2-adrenoceptor sensitivity. In: Typical and atypical antidepressants: Molecnhr mechanisms, ed. Costa, E. & Racagni, C., pp. 5562. Raven Press. [CBS, taEAS]
Sugrue, M. F. (1982 b) A study of the effects of chronic salbutamol on rat brain monoaminergic systems. journal of Pharmacy and Pharmacology 34:446–49. [taEAS]
Sugrue, M. F. (1982 c) A study of the sensitivity of rat brain alpha2-adrenoceptors during chronic antidepressant treatments. Naunyn-Schmiedebergs Archives of Pharmacology 320:9096. [rEAS, JV]
Sugrue, M. F. (1983) Do antidepressants possess a common mechanism of action? Biochemical Pharmacology, in press. [MFS]
Sulser, F. (1978 a) Functional aspects of the norepinephrine receptor coupled adenylate cyclase system in the limbic forebrain and its modification by drugs which precipitate or alleviate depression: Molecular approaches to an understanding of affective disorders. Pharmakopsychiatrie-NeuroPsychopharmakologie 11:4352. [HA, tarEAS]
Sulser, F. (1978 b) Tricyclic antidepressants: Animal pharmacology (biochemical and metabolic aspects). In: Handbook of psychopharmacology, ed. lversen, L. L., Iversen, S. D. & Snyder, S. H., pp. 157–98. Plenum Press. [AF]
Sulser, F. (1982) Antidepressant drug research: Its impact on neurobiology and psychobiology. In Typical and atypical antidepressants: Molecular mechanisms, ed. Costa, E. & Racagni, G., pp. 120. Raven Press. [taEAS]
Sulser, F., Vetulani, J. & Mobley, P. L. (1978) Mode of action of antidepressant drugs. Biochemical Pharmacology 27:257–61. [taEAS, MFS, JV]
Svedmyr, N. L. V., Larsson, S. A. & Thiringen, G. K. (1976) Development of “resistance” in beta-adrenergic receptors of asthmatic patients. Chest 69:479–83. [taEAS]
Svensson, T. H. (1980) Effect of chronic treatment with tricyclic antidepressant drugs on identified brain noradrenergic and serotoncrgic neurons. Acta Psychiatrica Scandinavica 61 (supp. 280):121–31. [taEAS]
Svensson, T. H. & Usdin, T. (1978) Feedback inhibition of brain noradrenaline neurons by tricyclic antidepressants: α-receptor mediation. Science 202:1089–91. [CBS, taEAS]
Swanson, L. W. (1981) A direct projection from Ammon's horn to prefrontal cortex in the rat. Brain Research 217:150–54. [YHH]
Swanson, L. W. & Cowan, W. M. (1977) An autoradiographic study of the organization of the efferent connections of the hippocampal formation in the rat. journal of Comparative Neurology 172:4984. [YHH]
Swillens, S., Lefort, E., Barber, R., Butcher, R. W. & Dumont, J. E. (1980) Consequences of hormone induced desensitization of adenylate cyclase in intact cells. Biochemical Journal 188:169–74. [US, tarEAS]
Takahashi, R., Tateishi, T., Yoshide, H. & Hironaka, I. (1982) Effect of chronic treatment with antidepressant drugs on scrotonergic receptor binding activity in normal and tetrabenazine depression rat, In: New vistas in depression, ed. Langer, S. Z., Takahasi, R., Segawa, T. & Briley, M., pp. 2936. Pergamon Press. [MHA]
Tang, S. W., Helmeste, D. M. & Stancer, H. C. (1978) The effect of acute and chronic desipramine and amitriptyline treatment on rat brain total 3- methoxy-4-hydroxyphenylglycol. Naunyn-Schmiedebergs Archives of Pharmacology 305:207–11. [taEAS]
Taylor, M. A. (1982) Indications for electroconvulsive treatment. In: Elect roconvulsive therapy: Biological foundations amid clinical applications, ed. Abrams, R. & Essman, W. B., PP. 740. Spectrum Publications. [taEAS]
Telner, J. I. & Singhal, R. F. (1981) Effects of nortriptyline treatment ois learned helplessness in the rat. Pharmiwcology Biochemistry and Behavior 14:823–26. [taEAS]
Terry, L. C., Crowley, W. R., Lynch, C., Longserre, C. & Johnson, M. D. (1982) Role of central epinephrine in regulation of anterior pituitary hormone secretion. Peptides 3:311–18. [KAR]
Thierry, A. M., Tassin, J. P., Blanc, G. & Glowinski, J. (1976) Selective activation of the mesocortical DA system by stress, Nature 263:242–44. [HA]
Thoenen, H. & Oesch, F. (1973) New enzyme synthesis as a long-term adaptation to increased transmitter utilization. In: New concepts in neurotransmitter regulation, ed. Mandell, A. J., P. 3351. Plenum Press. [taEAS]
Torda, T., Yamaguchi, I., Hirata, F., Kopin, I. J. & Axelrod, J. (1981 a) Mepacnne treatment prevents immobilization-induced desensitization of beta-adrenergic receptors in rat hypothalamus and brain stem. Brain Research 205:441–44. [taEAS]
Torda, T., (1981 b) Quinacrine-blocked desensitization of adrenoceptors after immobilization stress or repeated injection of isoproterenol in rats. journal of Pharmacology and Experimental Therapeutics 216:334–38. [taEAS]
U'Prichard, D. C. (1983) Characteristics of adrenergic presynaptic receptors in neurons. Paper presented by Dr. Sidney Hess Symposium organized by the Biochemical Pharmacology Discussion Group and the Section of Biochemistry of the New York Academy of Sciences, 05 24, New York City. [rEAS]
U'Prichard, D. C., Bechtel, W. D., Rouot, B. R. & Snyder, S. H. (1979) Multiple apparent alpha-moradrenergic receptor binding sites in rat brain: Effect of 6-hydroxydopamine. Molecular Pharmacology 16:4760. [US]
U'Prichard, D. C. & Kvetnansky, R. (1980) Central and peripheral adrenergic receptors in acute and repeated immobilization stress. In: Second international symposium on catecholamines and stress, ed. Usdin, E., Kvetnansky, B. & Kopin, I., pp. 299308. Elsevier/North Holland. [tarEAS]
Valzelli, L. & Garattini, S. (1968) Biogenic amines in discrete brain areas after treatment with monoamine oxidase inhibitor, journal of Neurochemistry 45:259–61. [WBE]
Vetulani, J. (1982) Adaptive changes as the mode of action of antidepressant treatments. In: Typical and atypical antidepressants: Molecular mechanisms, ed. Costa, E. & Racagni, C., pp. 2736. Raven Press. [CBS, JV]
Vetulani, J. (1983) Changes in responses of central aminergic structures after chronic ECS. In: Basic mechanisms of ECT action, ed. Lerer, B., Weiner, R. D. & Belmaker, R. H.. Libbey Co. [JV]
Vetulani, J., Antkiewmcz-Michaluk, L., Golembiowska-Nikitin, K., Michaluk, J., Pilc, A. & Rokosz, A. (1980) The effect of multiple imipramine administration on monoaminergic systems of the rat brain. Polish Journal of Pharmacology and Pharmacy 32:523–30. [JV]
Vetulani, J. & Pilc, A. (1982) Postdecapitation convulsions in the rat measured with an animex motility meter: Relation to central α-adrenoceptors. European Journal of Pharmacology 85:269–75. [JV]
Vetulani, J., Stawarz, R. J., Dingell, J. W. & Sulser, F. (1976) A possible common mechanism of action of antidepressant treatments: Reduction in the sensitivity of the noradrenergic cyclic AMP generating system in the rat limbic forebrain. Naunyn-Schmiedebergs Archives of Pharmacology 239:109–14. [YHH, LJS, taEAS]
Vetulani, J., Stawarz, R. J. & Sulser, F. (1976) Adaptive mechanisms of the noradrenergic cyclic AMP generating system in the limbic forebrain of the rat: Adaptation to persistent changes in the availability of norepinephrine (NE). Journal of Neurochemistry 27:661–66. [JV]
Vetulani, J. & Sulser, F. (1975) Action of various antidepressant treatments reduces reactivity of noradrenergic cyclic AMP-generating system in limbic forebrain. Nature 275:495–96.[JV]
von, Voigtlander P. F., Triezenberg, H. J. & Losey, E. G. (1978) Interaction between clonidine and antidepressant drugs: A method for identifying antidepressant-like agents. Ncuropharmacology 17:375–81. [rEAS, JV]
Von, Zersseis D. & Doerr, P. (1980) The role of the hypothalamo-pituitary-adrenal cortical system in psychiatric disorders. Advances in Biological Psychiatry 5:85106. [AF]
WaaI, H. J. (1967) Propranolol-induced depression. British Medical Journal 2:50. [taEAS]
Waldmeier, P. C. (1981) Noradrenergic transmission in depression: Under or over function? Pharmakopsychiatry 14:39. [taEAS]
Waterhouse, B. D., Moises, H. C., Yeh, H. H. & Woodward, D. J. (1982) Norepinephrine enhancement of inhibitory synaptic mechanisms in cerebellum and cerebral cortex; Mediation by beta adrenergic receptors. journal of Pharmacology and Experimental Therapeutics 221:495506. [taEAS]
Weiss, B., Heydorn, W. & Frazer, A. (1982) Modulation of the beta-adrenergic receptor-adenylate cyclase system following acute and repeated treatment with antidepressant. In: Typical and atypical antidepressants: Molecular mechanisms, ed. Costa, E. & Racagni, G., pp. 3753. Raven Press. [AF]
Welch, J., Kim, H., Fallon, S., Liebman, J., Chiodo, L. A. & Antelman, S. M. (1982) Do antidepressants induce dopamine autoreceptor subsensitivity? Nature 298:301–3. [rEAS]
Wells, H. (1962) Submandibular salivary gland weight increase by administration of isoproterenol to rats. American Journal of Physiology 202:423–28. [taEAS]
Wells, H. & Peronace, A. A. V. (1967) Functional hypertrophy and atrophy of the salivary glands in rats. American Journal of Physiology 212:247–51. [taEAS]
Vheatley, D. (1972) Potentiation of amitriptyline by thyroid hormone. Archives of General Psychiatry 26:229–33. [taEAS]
Whybrow, P. C. & Prange, A. J. (1981) A hypothesis of thyroid-catecholamine-receptor interaction. Archives of General Psychiatry 38:106–13. [taEAS]
Widlocher, D., Lecrubier, Y., Jouvent, R., Puech, A. J. & Simon, P. (1977) Antidepressant effect of salbutamol. Lancet 2:767–68.[taEAS]
Wielosz, M. (1981) Increased sensitivity to dopaminergic agonists after repeated electroconvulsive shock (ECS) in rats. Neuropharmacology 20:941–45. [tsEAS]
Williams, L. T., Lefkowitz, R. J., Hathaway, D. R., Watanabe, A. M. & Besch, H. R. (1977) Thyroid hormone regulation of beta-adrenergic receptor number. Journal of Biological Chemistry 252:2787–89. [rEAS]
Williams, R. S. (1980) Physical conditioning and membrane receptors for cardioregulatory hormones. Cardiovascular Research 14:177–82. [taEAS]
Wode-Helgodt, B., Fyro, B., Cullberg, B. & Sedvall, G. (1977) Effect of chlorpromazine treatment on monoamine metabolite levels in cerebrospinal fluid of psychotic patients. Acta Psychiatrica Scandinavica 56:129–42. [taEAS]
Wolfe, B. B., Harden, T. K., Sporn, J. B. & Molinoff, P. B. (1978) Presynaptic modulation of beta adrenergic receptors in rat cerebral cortex after treatment with antidepressants. Journal of Pharmacology and Experimental Therapeutics 207:446–57. [WBE, taEAS, Jv]
Wolfe, B. B., Minneman, K. P. & Molinoff, P. B. (1982) Selective increases in the density of cerebellar β1-adrenergic receptors. Brain Research 234:474–79. [WBE]
Woodward, D. J., Moises, H. C., Waterhouse, B. D., Hoffer, B. J. & Freedman, R. (1979) Modulatory actions of norepinephrine in the central nervous system. Federation Proceedings 38:2109–16. [taEAS]
Yamaguchi, I., Torda, T., Hirata, F. & Kopin, I. J., (1981) Adrenoceptor desensitization after immobilization stress or repeated injection of isoproterenol. American Journal of Physiology 240:H691–96. [taEAS]
Zacharko, R. M., Bowers, W., Kokkinidis, L. & Anisman, H. (1983) Region-specific reductions of intracranial self-stimulation after uncontrollable stress: Possible effects on reward processes. Behavioral Brain Research, in press. [HA]
Zelnik, T. C., Carcia-Sevilla, J. A., Cameron, O. C. & Smith, C. B. (1982) Clinical response to clonidine and imipramine, and platelet α2- adrenoreceptors in a case of agoraphobia with panic attacks. Biological Psychiatry 17:761–66. [CBS]