Hostname: page-component-76fb5796d-r6qrq Total loading time: 0 Render date: 2024-04-25T10:45:57.167Z Has data issue: false hasContentIssue false

Broccoli and grapefruit - part 1

Published online by Cambridge University Press:  11 September 2013

Get access

In a nutshell

Brassica vegetables (such as broccoli) have anti-carcinogen properties seen in animal, laboratory and observational studies.

Little data so far extends this to human clinical trials with these foods specifically. Genetic factors may be crucial in determining the extent to which individuals respond to this anti-cancer potential.

Type
Brief Report
Copyright
Copyright © Cambridge University Press 2006

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

2. Pan, SY. et al. A case-control study of diet and the risk of ovarian cancer. Cancer Epidemiol Biomarkers Prev. 2004 Sep;13(9):1521–7.Google Scholar
3. Kristal, AR. et al. Brassica vegetables and prostate cancer risk: a review of the epidemiological evidence. Nutr Cancer. 2002;42(1):19.Google Scholar
4. van Poppel, G. et al. Brassica vegetables and cancer prevention. Epidemiology and mechanisms. Adv Exp Med Biol. 1999;472:159–68.Google Scholar
5. Lynn, A. et al. Cruciferous vegetables and colo-rectal cancer. Proc Nutr Soc. 2006 Feb;65(1):135–44.Google Scholar
6. Verhoeven, DT. et al. Epidemiological studies on brassica vegetables and cancer risk. Cancer Epidemiol Biomarkers Prev. 1996 Sep;5(9):733–48.Google Scholar
7. Zhang, SM. et al. Intakes of fruits, vegetables, and related nutrients and the risk of non-Hodgkin's lymphoma among women. Cancer Epidemiol Biomarkers Prev. 2000 May;9(5):477–85.Google Scholar
8. Nestle, M. Broccoli sprouts as inducers of carcinogen-detoxifying enzyme systems: clinical, dietary, and policy implications. Proc Natl Acad Sci U S A. 1997 Oct 14;94(21):11149–51.Google Scholar
9. Finley, JW. Reduction of cancer risk by consumption of selenium-enriched plants: enrichment of broccoli with selenium increases the anticarcinogenic properties of broccoli. J Med Food. 2003 Spring;6(1):1926.Google Scholar
10. Anon. Arbor Clinical Nutrition Updates. Past issues: Selenium. http://www.nutritionupdates.org/pst/displaytopic.php?cat=52 Google Scholar
11. Stoewsand, GS. Bioactive organosulfur phytochemicals in Brassica oleracea vegetables--a review. Food Chem Toxicol. 1995 Jun;33(6):537–43.Google Scholar
12. Park, EJ. et al. Botanicals in cancer chemoprevention. Cancer Metastasis Rev. 2002;21(3–4):231–55.Google Scholar
13. Anon. Calcium-D-glucarate. Altern Med Rev. 2002 Aug;7(4):336–9.Google Scholar
14. Rose, P. et al. Protective effects of Asian green vegetables against oxidant induced cytotoxicity. World J Gastroenterol. 2005 Dec 28;11(48):7607–14.Google Scholar
15. Kensler, TW. et al. Effects of glucosinolate-rich broccoli sprouts on urinary levels of aflatoxin-DNA adducts and phenanthrene tetraols in a randomized clinical trial in He Zuo township, Qidong, People's Republic of China. Cancer Epidemiol Biomarkers Prev. 2005 Nov;14(11 Pt 1):2605–13.Google Scholar
16. Ahn, J. et al. Effects of glutathione S-transferase A1 (GSTA1) genotype and potential modifiers on breast cancer risk. Carcinogenesis. 2006 Apr 19; [Epub ahead of print]Google Scholar
17. Lin, HJ. et al. Glutathione transferase null genotype, broccoli, and lower prevalence of colorectal adenomas. Cancer Epidemiol Biomarkers Prev. 1998 Aug;7(8):647–52.Google Scholar
18. Fowke, JH. et al. Brassica vegetable consumption shifts estrogen metabolism in healthy postmenopausal women. Cancer Epidemiol Biomarkers Prev. 2000 Aug;9(8):773–9.Google Scholar
19. Michnovicz, JJ. et al. Changes in levels of urinary estrogen metabolites after oral indole-3-carbinol treatment in humans. J Natl Cancer Inst. 1997 May 21;89(10):718–23.Google Scholar
20. Opekun, AR. et al. In vivo tests of natural therapy, Tibetan yogurt or fresh broccoli, for Helicobacter pylori infection. Methods Find Exp Clin Pharmacol. 2005 Jun;27(5):327–9.CrossRefGoogle ScholarPubMed
21. Galan, MV. et al. Oral broccoli sprouts for the treatment of Helicobacter pylori infection: a preliminary report. Dig Dis Sci. 2004 Aug;49(7–8):1088–90.Google Scholar
22. Takai, M. et al. [LDL-cholesterol-lowering effect of a mixed green vegetable and fruit beverage containing broccoli and cabbage in hypercholesterolemic subjects] Rinsho Byori. 2003 Nov;51(11):1073–83.Google Scholar
23. Rosen, CA. et al. Indole-3-carbinol for recurrent respiratory papillomatosis: long-term results. J Voice. 2004 Jun;18(2):248–53.Google Scholar
24. Moeller, SM. et al. The potential role of dietary xanthophylls in cataract and age-related macular degeneration. J Am Coll Nutr. 2000 Oct;19(5 Suppl):522S527S.Google Scholar
25. Helman, AD. Nutrition and the aging eye. Arbor Clin Nutr Upd 2006;255: 13.Google Scholar
26. Brown, L. et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr. 1999 Oct;70(4):517–24.Google Scholar
27. Wilson, RD. et al. The use of folic acid for the prevention of neural tube defects and other congenital anomalies. J Obstet Gynaecol Can. 2003 Nov;25(11):959–73.Google Scholar
28. Kall, MA. et al. Effects of dietary broccoli on human in vivo drug metabolizing enzymes: evaluation of caffeine, oestrone and chlorzoxazone metabolism. Carcinogenesis. 1996 Apr;17(4):793–9.Google Scholar