Hostname: page-component-84b7d79bbc-g78kv Total loading time: 0 Render date: 2024-07-25T20:13:48.723Z Has data issue: false hasContentIssue false
  • English
  • Français

Anorexia nervosa 2: nutrition therapy

Published online by Cambridge University Press:  11 September 2013

Get access

In a nutshell

Issues for nutrition treatment of AN include: resistance to weight regain (e.g. from elevated REE) disproportionate central fat deposition, persistent immune, bone and muscle impacts.

Very few studies on nutrition in AN are RCTs. Those few that are do not give any consistent picture. Two small trials did find a benefit from zinc supplements.

Type
Brief Report
Information
Arbor Clinical Nutrition Updates , Volume 249 , April 2006 , pp. 1 - 4
Copyright
Copyright © Cambridge University Press 2006

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Krantz, MJ. et al. The paradox of normal serum albumin in anorexia nervosa: a case report. Int J Eat Disord. 2005 Apr;37(3):278–80.CrossRefGoogle ScholarPubMed
2. McClain, CJ. et al. Gastrointestinal and nutritional aspects of eating disorders. J Am Coll Nutr. 1993 Aug;12(4):466–74.CrossRefGoogle ScholarPubMed
3. Olmos, JM. et al. Vitamin D metabolism and serum binding proteins in anorexia nervosa. Bone. 1991;12(1):43–6.CrossRefGoogle ScholarPubMed
4. Attia, E. et al. Plasma tryptophan during weight restoration in patients with anorexia nervosa. Biol Psychiatry. 2005 Mar 15;57(6):674–8.CrossRefGoogle ScholarPubMed
5. Ohrmann, P. et al. Proton magnetic resonance spectroscopy in anorexia nervosa: correlations with cognition. Neuroreport. 2004 Mar 1;15(3):549–53.CrossRefGoogle ScholarPubMed
6. Fukusako, T. et al. [A case of secondary carnitine deficiency due to anorexia nervosa and severe liver damage] Rinsho Shinkeigaku. 1995 Jan;35(1):34–7.Google ScholarPubMed
7. Zak, A. et al. Composition of plasma fatty acids and non-cholesterol sterols in anorexia nervosa. Physiol Res. 2005;54(4):443–51.CrossRefGoogle ScholarPubMed
8. Ayton, AK. Dietary polyunsaturated fatty acids and anorexia nervosa: is there a link? Nutr Neurosci. 2004 Feb;7(1):1–12.CrossRefGoogle Scholar
9. Zak, A. et al. [Lipid metabolism in anorexia nervosa] Cas Lek Cesk. 2003;142(5):280–4.Google ScholarPubMed
10. Rock, CL. et al. Vitamin status of eating disorder patients: relationship to clinical indices and effect of treatment. Int J Eat Disord. 1995 Nov;18(3):257–62.3.0.CO;2-Q>CrossRefGoogle ScholarPubMed
11. Holman, RT. et al. Patients with anorexia nervosa demonstrate deficiencies of selected essential fatty acids, compensatory changes in nonessential fatty acids and decreased fluidity of plasma lipids. J Nutr. 1995 Apr;125(4):901–7.Google ScholarPubMed
12. Langan, SM. et al. Vitamin E, vitamin A and essential fatty acid status of patients hospitalized for anorexia nervosa. Am J Clin Nutr. 1985 May;41(5):1054–60.CrossRefGoogle ScholarPubMed
13. Arden, MR. et al. Effect of weight restoration on the dyslipoproteinemia of anorexia nervosa. J Adolesc Health Care. 1990 May;11(3):199–202.CrossRefGoogle ScholarPubMed
14. Roser, W. et al. Metabolic changes in the brain of patients with anorexia and bulimia nervosa as detected by proton magnetic resonance spectroscopy. Int J Eat Disord. 1999 Sep;26(2):119–36.3.0.CO;2-M>CrossRefGoogle ScholarPubMed
15. Nova, E. et al. Indicators of nutritional status in restricting-type anorexia nervosa patients: a 1-year follow-up study. Clin Nutr. 2004 Dec;23(6):1353–9.CrossRefGoogle ScholarPubMed
16. Kennedy, A. et al. Iron status and haematological changes in adolescent female inpatients with anorexia nervosa. J Paediatr Child Health. 2004 Aug;40(8):430–2.CrossRefGoogle ScholarPubMed
17. Van Binsbergen, CJ. et al. Nutritional status in anorexia nervosa: clinical chemistry, vitamins, iron and zinc. Eur J Clin Nutr. 1988 Nov;42(11):929–37.Google ScholarPubMed
18. Thibault, L. et al. The nutritional status of subjects with anorexia nervosa. Int J Vitam Nutr Res. 1987;57(4):447–52.Google ScholarPubMed
19. Birmingham, CL. et al. Hypomagnesemia during refeeding in anorexia nervosa. Eat Weight Disord. 2004 Sep;9(3):236–7.CrossRefGoogle ScholarPubMed
20. Hadigan, CM. et al. Assessment of macronutrient and micronutrient intake in women with anorexia nervosa. Int J Eat Disord. 2000 Nov;28(3):284–92.3.0.CO;2-G>CrossRefGoogle ScholarPubMed
21. Fonseca, V. et al. Electrolyte disturbances and cardiac failure with hypomagnesaemia in anorexia nervosa. Br Med J (Clin Res Ed). 1985 Dec 14;291(6510):1680–2.CrossRefGoogle ScholarPubMed
22. Hall, RC. et al. Hypomagnesemia in eating disorder patients: clinical signs and symptoms. Psychiatr Med. 1989;7(4):193–203.Google ScholarPubMed
23. Casper, RC. et al. An evaluation of trace metals, vitamins, and taste function in anorexia nervosa. Am J Clin Nutr. 1980 Aug;33(8):1801–8.CrossRefGoogle ScholarPubMed
24. Levenson, CW. Zinc regulation of food intake: new insights on the role of neuropeptide Y. Nutr Rev. 2003 Jul;61(7):247–9.Google ScholarPubMed
25. Bakan, R. et al. Dietary zinc intake of vegetarian and nonvegetarian patients with anorexia nervosa. Int J Eat Disord. 1993 Mar;13(2):229–33.3.0.CO;2-1>CrossRefGoogle ScholarPubMed
26. Lask, B. et al. Zinc deficiency and childhood-onset anorexia nervosa. J Clin Psychiatry. 1993 Feb;54(2):63–6.Google ScholarPubMed
27. McClain, CJ. et al. Zinc status before and after zinc supplementation of eating disorder patients. J Am Coll Nutr. 1992 Dec;11(6):694–700.CrossRefGoogle ScholarPubMed
28. Katz, RL. et al. Zinc deficiency in anorexia nervosa. J Adolesc Health Care. 1987 Sep;8(5):400–6.CrossRefGoogle ScholarPubMed
29. Humphries, L. et al. Zinc deficiency and eating disorders. J Clin Psychiatry. 1989 Dec;50(12):456–9.Google ScholarPubMed
30. Esca, SA. et al. Kwashiorkor-like zinc deficiency syndrome in anorexia nervosa. Acta Derm Venereol. 1979;59(4):361–4.CrossRefGoogle ScholarPubMed
31. Roijen, SB. et al. [Zinc in patients with anorexia nervosa] Ugeskr Laeger. 1991 Mar 4;153(10):721–3.Google ScholarPubMed
32. Varela, P. et al. Zinc status in anorexia nervosa. Ann Nutr Metab. 1992: 36(4):197–202.CrossRefGoogle ScholarPubMed
33. Birmingham, CL. et al. Controlled trial of zinc supplementation in anorexia nervosa. Int J Eat Disord. 1994 Apr;15(3):251–5.3.0.CO;2-#>CrossRefGoogle ScholarPubMed
34. Safai-Kutti, S. Oral zinc supplementation in anorexia nervosa. Acta Psychiatr Scand Suppl. 1990;361:14–7.CrossRefGoogle ScholarPubMed
35. Moyano, D. et al. Plasma total-homocysteine in anorexia nervosa. Eur J Clin Nutr. 1998 Mar;52(3):172–5.CrossRefGoogle ScholarPubMed
36. Castro, J. et al. Persistence of nutritional deficiencies after short-term weight recovery in adolescents with anorexia nervosa. Int J Eat Disord. 2004 Mar;35(2):169–78.CrossRefGoogle ScholarPubMed
37. Winston, AP. et al. Prevalence of thiamin deficiency in anorexia nervosa. Int J Eat Disord. 2000 Dec;28(4):451–4.3.0.CO;2-I>CrossRefGoogle ScholarPubMed
38. Capo-chichi, CD. et al. Riboflavin and riboflavin-derived cofactors in adolescent girls with anorexia nervosa. Am J Clin Nutr. 1999 Apr;69(4):672–8.CrossRefGoogle ScholarPubMed
39. Curran-Celentano, J. et al. Alterations in vitamin A and thyroid hormone status in anorexia nervosa and associated disorders. Am J Clin Nutr. 1985 Dec;42(6):1183–91.CrossRefGoogle ScholarPubMed
40. Vaisman, N. et al. Vitamin A metabolism in plasma of normal and anorectic women. Eur J Clin Nutr. 1992 Dec;46(12):873–8.Google ScholarPubMed
41. Christopher, K. et al. Early scurvy complicating anorexia nervosa. South Med J. 2002 Sep;95(9):1065–6.CrossRefGoogle ScholarPubMed
42. Aarskog, D. et al. Plasma concentrations of vitamin D metabolites in pubertal girls with anorexia nervosa. Acta Endocrinol Suppl (Copenh). 1986;279:458–67.Google ScholarPubMed
43. Fonseca, VA. et al. Vitamin D deficiency and low osteocalcin concentrations in anorexia nervosa. J Clin Pathol. 1988 Feb;41(2):195–7.CrossRefGoogle ScholarPubMed
44. Moyano, D. et al. Antioxidant status in anorexia nervosa. Int J Eat Disord. 1999 Jan;25(1):99–103.3.0.CO;2-N>CrossRefGoogle ScholarPubMed
45. Golden, NH. et al. Nutritional rehabilitation of anorexia nervosa. Goals and dangers. Int J Adolesc Med Health. 2004 Apr-Jun;16(2):131–44.CrossRefGoogle ScholarPubMed
46. Kaye, WH. et al. Anxiolytic effects of acute tryptophan depletion in anorexia nervosa. Int J Eat Disord. 2003 Apr;33(3):257–67; discussion 268-70.CrossRefGoogle ScholarPubMed
47. Andrewes, DG. et al. Computerised psychoeducation for patients with eating disorders. Aust N Z J Psychiatry. 1996 Aug;30(4):492–7.CrossRefGoogle ScholarPubMed
48. Hall, A. et al. Brief psychotherapy in the treatment of anorexia nervosa. Outcome at one year. Br J Psychiatry. 1987 Aug;151:185–91.CrossRefGoogle ScholarPubMed
49. Van Wymelbeke, V. et al. Factors associated with the increase in resting energy expenditure during refeeding in malnourished anorexia nervosa patients. Am J Clin Nutr. 2004 Dec;80(6):1469–77.CrossRefGoogle ScholarPubMed
50. Salisbury, JJ. et al. Refeeding, metabolic rate, and weight gain in anorexia nervosa: a review. Int J Eat Disord. 1995 May;17(4):337–45.3.0.CO;2-Q>CrossRefGoogle ScholarPubMed
51. Herpertz, S. et al. Longitudinal changes of circadian leptin, insulin and cortisol plasma levels and their correlation during refeeding in patients with anorexia nervosa. Eur J Endocrinol. 2000 Apr;142(4):373–9.CrossRefGoogle ScholarPubMed
52. Munoz, MT. et al. New concepts in anorexia nervosa. J Pediatr Endocrinol Metab. 2004 Mar;17 Suppl 3:473–80.Google Scholar
53. Misra, M. et al. Regional body composition in adolescents with anorexia nervosa and changes with weight recovery. Am J Clin Nutr. 2003 Jun;77(6):1361–7.CrossRefGoogle ScholarPubMed
54. Grinspoon, S. et al. Changes in regional fat redistribution and the effects of estrogen during spontaneous weight gain in women with anorexia nervosa. Am J Clin Nutr. 2001 May;73(5):865–9.CrossRefGoogle ScholarPubMed
55. Rigaud, D. et al. Refeeding improves muscle performance without normalization of muscle mass and oxygen consumption in anorexia nervosa patients. Am J Clin Nutr. 1997 Jun;65(6):1845–51.CrossRefGoogle ScholarPubMed
56. Marcos, A. et al. Interactions between nutrition and immunity in anorexia nervosa: a 1-y follow-up study. Am J Clin Nutr. 1997 Aug;66(2):485S·490S.CrossRefGoogle ScholarPubMed
57. Forbes, GB. et al. Body composition changes during recovery from anorexia nervosa: comparison of two dietary regimes. Am J Clin Nutr. 1984 Dec;40(6):1137–45.CrossRefGoogle ScholarPubMed
58. Ayton, AK. et al. A pilot open case series of ethyl-EPA supplementation in the treatment of anorexia nervosa. Prostaglandins Leukot Essent Fatty Acids. 2004 Oct;71(4):205–9.CrossRefGoogle ScholarPubMed
59. Mika, C. et al. Dietary treatment enhances bone formation in malnourished patients. J Gravit Physiol. 2002 Jul;9(1):P331–2.Google ScholarPubMed
60. Korkina, MV. et al. [Effects of carnitine and cobamamide on the dynamics of mental work capacity in patients with anorexia nervosa] Zh Nevropatol Psikhiatr Im S S Korsakova. 1992;92(2):99–102.Google ScholarPubMed
61. Imbierowicz, K. et al. High-caloric supplements in anorexia treatment. Int J Eat Disord. 2002 Sep;32(2):135–45.CrossRefGoogle ScholarPubMed
62. Pederson, KJ. et al. Towards the pharmacotherapy of eating disorders. Expert Opin Pharmacother. 2003 Oct;4(10):1659–78.CrossRefGoogle ScholarPubMed
63. Russell, J. Treating anorexia nervosa. BMJ. 1995 Sep 2;311(7005):584.CrossRefGoogle ScholarPubMed
64. Mayer, L. Body composition and anorexia nervosa: does physiology explain psychology? Am J Clin Nutr. 2001 May;73(5):851–2.CrossRefGoogle ScholarPubMed
65. Mayer, L. Body composition and anorexia nervosa: does physiology explain psychology? Am J Clin Nutr. 2001 May;73(5):851–2.CrossRefGoogle ScholarPubMed
66. Bergh, C. et al. Randomized controlled trial of a treatment for anorexia and bulimia nervosa. Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9486–91.CrossRefGoogle ScholarPubMed