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Assignment of the human fast skeletal muscle troponin C gene (TNNC2) between D20S721 and GCT10F11 on chromosome 20 by somatic cell hybrid analysis

Published online by Cambridge University Press:  01 September 1997

P. J. TOWNSEND
Affiliation:
Imperial College School of Medicine at the National Heart and Lung Institute, Dovehouse Street, London SW3 6LY
M. H. YACOUB
Affiliation:
Imperial College School of Medicine at the National Heart and Lung Institute, Dovehouse Street, London SW3 6LY
P. J. R. BARTON
Affiliation:
Imperial College School of Medicine at the National Heart and Lung Institute, Dovehouse Street, London SW3 6LY
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Abstract

The chromosomal location of the human fast skeletal muscle troponin C (TNNC2) gene was determined using somatic cell hybrids. PCR-based analysis of a ‘monochromosomal’ hybrid panel identified the presence of the TNNC2 gene on human chromosome 20 and subsequent analysis of the Genebridge4 radiation hybrid panel located the gene between D20S721 and GCT10F11 with a lod score of >3.

Type
SHORT COMMUNICATION
Copyright
© University College London 1997

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