Hostname: page-component-77c89778f8-swr86 Total loading time: 0 Render date: 2024-07-20T08:37:42.107Z Has data issue: false hasContentIssue false
  • English
  • Français

Anxiolytic Drugs Inhibit Hyperthermia Induced by Handling in Farmed Silver Foxes (Vulpes Vulpes)

Published online by Cambridge University Press:  11 January 2023

R O Moe  and
M Bakken
R O Moe
Affiliation:
Research Farm, Norwegian College of Veterinary Medicine, Rustadveien 131, N-1380 Heggedal, Norway
M Bakken
Affiliation:
Department of Animal Science, Agricultural University of Norway, PO Box 5025, N-1432 Ås, Norway
Get access Rights & Permissions [Opens in a new window]

Abstract

As a contribution to the ongoing work aiming to improve welfare in farmed silver foxes (Vulpes vulpes), the present study attempted to investigate stress-induced hyperthermia (SIH) as a physiological indicator of fear or anxiety in this species. Measuring rectal temperature (Trec) served as a stressor and immediately elicited SIH. Then, the foxes received either the anxiolytic drugs, diazepam or buspirone, or sterile saline. Trec in the foxes treated with diazepam and buspirone was significantly lower 90min after treatment. The results indicate that SIH induced by handling was attenuated by anxiolytic drugs, which supports the hypothesis that anxiety contributes to the development of SIH.

Keywords

animal welfarefearsilver foxstress-induced hyperthermia
Type
Short Communication
Information
Animal Welfare , Volume 7 , Issue 1 , February 1998 , pp. 97 - 100
Copyright
© 1998 Universities Federation for Animal Welfare

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bakken, M, Moe, R O and Smith, A 1993 Radio telemetry: a method of evaluating stress and learning ability in the silver fox (Vulpes vulpes). In: Nichelman, M, Wierenga, H K and Braun, S (eds) Proceedings of the International Congress on Applied Ethology, Berlin 1993 pp 591–593. Humboldt University: Berlin, GermanyGoogle Scholar
Belyaev, D K 1979 Destabilising selection as a factor in domestication. Journal of Heredity 70: 301–308CrossRefGoogle Scholar
Borsini, F, Lecci, A, Volterra, G and Meli, A 1989 A model to measure anticipatory anxiety in mice? Psychopharmacology 98: 207–211CrossRefGoogle Scholar
Borsini, F, Brambilla, A, Cesana, R and Donetti, A 1993 The effect of DAU 6215, a novel 5HT-3 antagonist, in animal models of anxiety. Pharmacological Research 27: 151–163CrossRefGoogle ScholarPubMed
Kluger, M J, O’Reilly, B, Shope, T R and Vander, A J 1987 Further evidence that stress hyperthermia is a fever. Physiology & Behavior 39: 763–766CrossRefGoogle ScholarPubMed
Lecci, A, Borsini, F, Mancinelli, A, D’Aranno, V, Stasi, M A, Volterra, G and Meli, A 1990a Effect of serotoninergic drugs on stress-induced hyperthermia (SIH) in mice. Journal of Neural Transmission 82: 219–230CrossRefGoogle ScholarPubMed
Lecci, A, Borsini, F, Volterra, G and Meli, A 1990b Pharmacological validation of a novel animal model of anticipatory anxiety in mice. Psychopharmacology 101: 255–261CrossRefGoogle ScholarPubMed
Mennini, T, Caccia, S and Garattini, S 1987 Mechanisms of action of anxiolytic drugs. In: Jucker E (ed) Progress in drug research, Volume 31. pp 315–347. Birkhäuser: Basel, SwitzerlandCrossRefGoogle Scholar
Moe, R O and Bakken, M 1997a Effects of handling and physical restraint on rectal temperature, Cortisol, glucose and leucocyte counts in the silver fox (Vulpes vulpes) Acta Veterinaria Scandinavica 38: 29–39Google ScholarPubMed
Moe, R O and Bakken, M 1997b Effect of indomethacin on LPS-induced fever and on hyperthermia induced by physical restraint in the silver fox (Vulpes vulpes). Journal of thermal Biology 22: 79–85CrossRefGoogle Scholar
Pedersen, V 1994 Long-term effects of different handling procedures on behavioural, physiological, and production-related parameters in silver foxes. Applied Animal Behaviour Science 40: 285–296CrossRefGoogle Scholar
Plyusnina, I Z, Oskina, N and Trut, L N 1991 An analysis of fear and aggression during early development of behaviour in silver foxes (Vulpes vulpes). Applied Animal Behaviour Science 32: 253–268CrossRefGoogle Scholar
Statistical Analysis Systems Institute Inc 1986 SAS User’s Guide: Statistics Version 6 Edition. Statistical Analysis Systems Institute Inc: Cary, North Carolina, USAGoogle Scholar