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Reproductive performance over repeated parities of lines of mice selected for appetite, lean growth and fatness

Published online by Cambridge University Press:  02 September 2010

F. D. Brien  and
W. G. Hill
F. D. Brien
Affiliation:
Institute of Animal Genetics, University of Edinburgh, West Mains Road, Edinburgh EH9 3JN
W. G. Hill
Affiliation:
Institute of Animal Genetics, University of Edinburgh, West Mains Road, Edinburgh EH9 3JN
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Abstract

Female reproductive performance over four parities was studied for lines of mice selected for one three criteria: appetite (A), total lean mass (P), or proportion of fat (F). Female mice were first bred 8 weeks of age, and thereafter at intervals of about 7 weeks until fourth parity when they were dissected in late pregnancy to measure components of litter size.

The high A lines had higher litter sizes at the first three parities and higher ovulation rates, numbers of implantation sites and live foetuses at the fourth parity than the low A lines. The high P lines were also higher than the low P lines for each of these traits. In contrast, litter sizes and ovulation rates differed little between the high and low F lines. Fitting body weight as a covariate removed the high-low differences in ovulation rate and litter size between the P lines, but not all the differences between the A lines.

Pre-implantation survival at the fourth parity was slightly lower in the high than in low A and in high than in low P lines. Differences in post-implantation survival were very small. No component of prenatal survival differed substantially at fourth parity between the high and low F lines.

Differences in fertility at each parity and the percentages of females surviving to the end of the study were small. At each litter, dams of the high A lines produced heavier total weights of litters at 12 and 21 days than dams of the low A lines and the corresponding high-low differences in the P lines were larger. There were only small differences in these traits between the F lines. When litter size, fertility and survival were summed over parities, the average total number of young produced per female was substantially higher in the high than in the low A lines (5·0 young born alive or dead) and the P lines (7·2), but the high-low difference was small in the F lines (2-0). For all lines, litter size at first parity gave a reliable indication of reproductive rate during a major portion of the reproductive lifespan.

Type
Research Article
Information
Animal Production , Volume 42 , Issue 3 , June 1986 , pp. 397 - 410
Copyright
Copyright © British Society of Animal Science 1986

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