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The effect of age on halothane susceptibility in pigs

Published online by Cambridge University Press:  02 September 2010

A. E. Carden  and
A. J. Webb
A. E. Carden
Affiliation:
AFRC Animal Breeding Research Organisation, West Mains Road, Edinburgh EH9 3JQ
A. J. Webb
Affiliation:
AFRC Animal Breeding Research Organisation, West Mains Road, Edinburgh EH9 3JQ
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Abstract

The effect of age on incidence of susceptibility to halothane anaesthesia in pigs was studied on animals that were repeatedly exposed to the anaesthetic. In three trials, 232 Piétrain/Hampshire and 201 Landrace pigs were given three 3-min halothane tests, at 19, 35 and 54 days of age. In a fourth trial 253 Landrace pigs received four 5-min tests, at 21, 35, 49 and 63 days. All pigs were offspring of positive × positive matings. Maximum-likelihood estimates of the probability of positive reactions were 0·47, 0·73 and 0·88 at the three ages in Pietrain/Hampshire; 0·20, 0·63 and 0·60 in the first Landrance trial; and 0·64, 0·86, 0·84 and 0·90 in the second Landrace trial. Thus, in all trials, the incidence of halothane positive reactions increased with age. In both breeds and at all ages, the incidence was lower in males than in females.

Type
Research Article
Information
Animal Production , Volume 38 , Issue 3 , June 1984 , pp. 469 - 475
Copyright
Copyright © British Society of Animal Science 1984

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References

REFERENCES

Baker, R. J. and Nelder, J. A. 1978. The GLIM System, Release 3. Numerical Algorithms Group, Oxford.Google Scholar
Batschelet, E. 1963. Testing hypotheses and estimating parameters in human genetics if the age of onset is random. Biometrika 50: 265–279.CrossRefGoogle Scholar
Carden, A. E. 1982. The genetics of halothane sensitivity in pigs. Ph.D Thesis, Univ. Edinb.Google Scholar
Carden, A. E., Hill, W. G. and Webb, A. J. 1983. The inheritance of halothane susceptibility in pigs. Gènet. Sèl. Evol. 15: 65–81.Google ScholarPubMed
Falconer, D. S. 1967. The inheritance of liability to diseases with variable age of onset, with particular reference to diabetes mellitus. Ann. hum. Genet. 31:1–20.CrossRefGoogle ScholarPubMed
Finney, D. J. 1970. Statistical Method in Biological Assay. 2nd ed. Griffin, London.Google Scholar
Mabry, J. W., Christian, L. L., Kuhlers, D. L. 1981.Inheritance of porcine stress syndrome. J. Hered. 72: 429–430.Google ScholarPubMed
Mabry, J. W., Christian, L. L., Kuhlers, D. L. and Rasmusen, B. A. 1983. Prediction of susceptibility to the porcine stress syndrome. J. Hered. 74: 23–26.CrossRefGoogle Scholar
Smith, C. and Bampton, P. R. 1977. Inheritance of reaction to halothane anaesthesia in pigs. Genet. Res 29: 287–292.CrossRefGoogle ScholarPubMed
Webb, A. J. 1980. The effect of age on the expression of the halothane gene in pigs. 31st A. Mtg Eur. Ass. Anim. Prod., Munich, Paper P5/6.22.Google Scholar
Webb, A. J. 1981. The halothane sensitivity test. In Porcine Stress and Meat Quality: Causes and Possible Solutions to the Problems (ed. Frøystein, T., Slinke, E. and Standal, N.), pp. 105–124. Agricultural Food Research Society, ås.Google Scholar
Webb, A. J., Carden, A. E., Smith, C. and Imlah, P. 1982. Porcine stress syndrome in pig breeding. Proc. 2nd Wld Congr. Genet. Appl. Livest. Prod., Madrid, Vol. 5, pp. 588–608.Google Scholar
Webb, A. J. and Jordan, C. H. C. 1978. Halothane sensitivity as a field test for stress-susceptibility in the pig. Anim. Prod. 26: 157–168.Google Scholar