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Changes in the composition of plasma very low density lipoprotein during pregnancy and lactation in genetic lines of pigs

Published online by Cambridge University Press:  02 September 2010

M. M. Wright ,
I. J. Lean ,
E. Herrera  and
P. F. Dodds
M. M. Wright
Affiliation:
Department of Biological Sciences
I. J. Lean
Affiliation:
Department of Agriculture, Wye College, University of London, Wye, Ashford, Kent TN25 5AH
E. Herrera
Affiliation:
Departamento de Investigacíon, Centro Ramón y Cajal, 28034-Madrid, Spain
P. F. Dodds
Affiliation:
Department of Biological Sciences
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Abstract

Plasma very low density lipoproteins (VLDL) of gilts were separated into two sub fractions according to their affinity for heparin. The proportion of VLDL present as subfraction 2 (higher affinity for heparin) varied, according to the genetic line of the pigs, between 0·21 and 0·78 in virgin gilts. The proportions were related to the variation in piglet survival in the same nine genetic lines by a quadratic equation, which predicted that greater than 90% survival to weaning was to be found in piglets born to gilts having between about 0·3 and 0·7 of their VLDL as subfraction 2. This observation suggests a simple measurement that could be used in the selection of sows for a breeding programme. The proportion of subfraction 2 fell throughout pregnancy in each of three genetic lines measured and only returned to pre-pregnant values after weaning: these changes did not correlate with the changes in the lipid composition of plasma VLDL measured during pregnancy and lactation. The findings suggest a role for the VLDL subfractions in controlling the nutrition of the neonatal pig.

Keywords

lactationlipoproteinsplasma lipidspregnancysows
Type
Research Article
Information
Animal Science , Volume 61 , Issue 2 , October 1995 , pp. 361 - 368
Copyright
Copyright © British Society of Animal Science 1995

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