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Report on a Pair of Male Monozygotic Twins Concordant for Schizophrenia

  • Henry T. Lynch (a1), Louis Cohen (a2), Arnold R. Kaplan (a3) and Jane Lynch (a3)

Summary

A pair of MZ twins with diagnoses of chronic simple schizophrenia has been studied from the genetic, social, medical, and psychiatric standpoint by members of the several professions. Clinical psychologists studied the patients independently and on the basis of psychometric and projective tests found a remarkable similarity in personality profiles. An in-depth family study failed to reveal any evidence of psychiatric disease in other relatives. Consanguinity was absent. The family unit is typical of that described frequently for a schizophrenogenic household, i.e., dominant mother, passive father. Genetic etiologies are discussed in context with occurrence of schizophrenia in MZ twins in this particular family setting.

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Copyright

Corresponding author

Department of Preventive Medicine and Public Health, Creighton University School of Medicine, 2500 California Street, Omaha, Nebraska 68131, USA

References

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Allen, G. 1954. Discussion. Proceedings of the Conference on Problems and Methods in Human Genetics. Am. J. Hum. Genet., 6: 162164.
Bleuler, M. 1968. A 23-year longitudinal study of 208 schizophrenics and impressions in regard to the nature of schizophrenia. In Rosenthal, D. and Kety, S.S. (Eds.): The Transmission of Schizophrenia. Pergamon Press, Oxford.
Bleuler, M. 1970. Some results of research in schizophrenia. Behav. Sci., 15: 211219.
Böök, J.A. 1953. A genetic and neuropsychiatrie investigation of a North-Swedish population, with special regard to schizophrenia and mental deficiency. Acta Genet. (Basel), 4: 1–100, 133–139, and 345414.
Gottesman, I.I., Shields, J. 1967. A polygenic theory of schizophrenia. Proc. Natl. Acad. Sci. USA., 58: 199205.
Hurst, L.A. 1972. Hypothesis of a single-locus recessive genotype for schizophrenia. In Kaplan, A.R. (Ed.): Genetic Factors in “Schizophrenia”. Charles C. Thomas, Springfield.
Kallmann, F.J. 1946. The genetic theory of schizophrenia: an analysis of 691 schizophrenic twin index families. Am. J. Psychiatry, 103: 309322, 1946.
Kallmann, F.J. 1953. Heredity in Health and Mental Disorder. Norton, New York.
Kaplan, A.R. 1972. Introduction; and, Conclusion: genetics and schizophrenia. In Kaplan, A.R. (Ed.): Genetic Factors in “Schizophrenia”. Charles C. Thomas, Springfield.
Karlsson, J. 1966. The Biologic Basis of Schizophrenia. Charles C. Thomas, Springfield.
Mitsuda, H. 1967. Clinical Genetics in Psychiatry. Igaku Shoin, Tokyo.
Ödegård, Ö. 1963. The psychiatric disease entities in the light of a genetic investigation. Acta Psychiatr. Scand., Suppl, 169: 94104.
Ödegård, Ö. 1972. The multifactoral theory of inheritance of predisposition to schizophrenia. In Kaplan, A.R. (Ed.): Genetic Factors in “Schizophrenia”. Charles C. Thomas, Springfield.
Pollin, W. 1972. A new approach to the use of twin study data, in studies of the pathogenesis of schzoi-phrenia and neurosis. In Kaplan, A.R. (Ed.): Genetic Factors in “Schizophrenia”. Charles C. Thomas, Springfield.
Pollin, W., Stabenau, J.R., Mosher, L., Tupin, J. 1966. Life history differences in identical twins discordant for schizophrenia. Am. J. Orthopsychiatry, 36: 492509.
Pollin, W., Stabenau, J.R. 1968. Biological, psychological and historical differences in a series of monozygotic twins discordant for schizophrenia. In Rosenthal, D. and Kety, S.S. (Eds.): The Transmission of Schizophrenia. Pergamon Press, Oxford.
Slater, E. 1958. The monogenic theory of schizophrenia. Acta Genet. (Basel), 8: 5056.
Stabenau, J.R., Pollin, W. 1967. Early characteristics of monozygotic twins discordant for schizophrenia. Arch. Gen. Psychiatry, 17: 723734.
Stierlin, H. 1972. The impact of relational vicissitudes on the life course of one schizophrenic quadruplet. In Kaplan, A.R. (Ed.): Genetic Factors in “Schizophrenia”. Charles C. Thomas, Springfield.

Report on a Pair of Male Monozygotic Twins Concordant for Schizophrenia

  • Henry T. Lynch (a1), Louis Cohen (a2), Arnold R. Kaplan (a3) and Jane Lynch (a3)

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