Hostname: page-component-77c89778f8-rkxrd Total loading time: 0 Render date: 2024-07-19T06:10:43.107Z Has data issue: false hasContentIssue false
  • English
  • Français

Morbo di Addison familiare (Iposurrenalismo cronico « parzialmente compensato » insorto in padre e figlio dopo l'influenza asiatica)1

Published online by Cambridge University Press:  01 August 2014

R. Toccafondi  and
A. Borghi
R. Toccafondi
Affiliation:
Istituto di Patologia Speciale Medica e Metodologia Clinica dell'Università di Firenze
A. Borghi
Affiliation:
Istituto di Patologia Speciale Medica e Metodologia Clinica dell'Università di Firenze

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Two familial cases (father and son) of Addison disease, occurred after « asian influenza », are reported.

Clinical data suggest tat the pathological basis for adrenal insufficiency could be the so-called « simple fibrosclerosis » and that virus infection has acted as a precipitating factor of an underlying adrenal meyopragy, since both patients as well as other members of the same familyi have a hyperpigmentated skin.

The two patients have shown a Addison syndrome « partially compensate » with incomplete symptomatology for lack of functional adrenal reserve which has been detected only by ACTH stimulation (which was inefficient).

As far as we know, this is the first report of a chronic hypercorticalism occurred in the father and one of his sons.

Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 11 , Issue 4 , October 1962 , pp. 407 - 417
Copyright
Copyright © The International Society for Twin Studies 1962

Footnotes

1

Il lavoro spetta in parti uguali ai due autori. II Direttore.

References

Bibliografia

1. Abu-Haydar, N., St. Marc, J. Q., Reddy, W. J., Laidlaw, J. G. e Thorn, G. W.: Adrenocortical insufficiency with normal basal levels of urinary 17-hydroxycorticosteroids. Diagnostic implications. J. Clin. Endocrinol. & Metab., 18: 121, 1958.Google Scholar
2. Andrews, F. W.: St. Bartolomeus Hosp. Rep., 27: 109, 1891.Google Scholar
3. Bell-Fletscher, : in Ass. Med. J., pag. 1012, 1856 (citato da Lewin).Google Scholar
4. Berlin, R.: Addison's diseases: familial incidence and occurence in association with pernicious anemia. Acta Med. Scand., 144: 1, 1952.Google Scholar
5. Bie, J.: Morbus Addisonii hos born: forekomst hos to soskende. Nord. Med., 55: 193, 1956.Google Scholar
6. Bittorx, H.: Die Pathologie der Nebennieren und des Morbus Addison. Breslau, 1907.Google Scholar
7. Boenheim, F.: Ueber chronische benigne Hypofunktion der Nebennieren; Ein Beitrag zur Kenntniss der vegetativ-endocrinen Fferedodegenartion. Klin. Wschr., 4: 1159, 1925.Google Scholar
8. Borghi, A.: in Teodori U. e coll.: Problemi di genetica medica in campo endocrinologico. Atti del VII Gongresso Nazionale della Società Italiana di Endocrinologia. Firenze, 1957.Google Scholar
9. Borghini, G.: Morbo di Addison familiare. Giorn. Clin. Med., 18: 587, 1937.Google Scholar
10. Briggs, J. N., Goodwin, J. F. e Wilson, A.: Addison's disease occurring in two brothers. Brit. Med. J., 4698: 115, 1951.Google Scholar
11. Brochner-Mortensen, K.: Familial occurrence of Addison's disease. Acta Med. Scand., 156: 205, 1956.Google Scholar
12. Colucci, C. F., Jacono, G. e Villari, A.: Studio di alcuni aspetti della funzionalità corticosurrenale nel corso dell'influenza. Folia endocrinol., 7: 455, 1954.Google Scholar
13. Craig, J. M., Schiff, L. H., e Boone, J. E.: Chronic moniliasis associated with Addison's disease. Am. J. Dis. Child., 89: 669, 1955.Google Scholar
14. Croom, D. H.: Addisonism as a family disease. Lancet, 1: 603, 1909.Google Scholar
15. Curschmann, H.: Ueber familiären Morbus Addison und Addisonismus. Wien. Med. Wschr., 90: 326, 1940.Google Scholar
16. Espargne, A.: in Ann. Clin. Montpellier, 4: 278, 1857 (citato da Levin).Google Scholar
17. Fahr, T. e Reiche, F.: Zur Brage des Morbus Addison. Frankf. Ztschr. e. Path., 22: 231, 1919.Google Scholar
18. Feuerstein, E.: Wien. Bl., 35, 1888 (citato da Lewin).Google Scholar
19. Fleming, R. A. e Miller, J.: A family with Addison's disease. Brit. Med. J., 1: 1014, 1900.Google Scholar
20. Gonzalo-Sanz, L. M.: Resistencia inespecifica del organismo y lesiones cortico-suprarrenales. Rev. Espan. Fisiol., 12: 33, 1956.Google Scholar
21. Green, E. M.: Repost of a case of Addison's disease. Medical Rec., 61: 94, 1902.Google Scholar
22. Guttman, P. H.: Addison's disease. Arch. Path., 10: 742, 1930.Google Scholar
23. Hewitt, P. H.: Addison's disease occurring in sisters. Brit. Med. J., 2: 1530, 1957.Google Scholar
24. Kief, H.: Morphologische Veranderungen der Nebennirenrinde bei Grippenpneumonie und ihrc Funktionelle Bedeutung. Zbl. Allg. Path., 87: 387, 1951.Google Scholar
25. Kovacs, A.: Beiderseitige akutc Nebenniersnblutung bei Influenza. Frankf. Ztschr. f. Path., 38: 387, 1929.Google Scholar
26. Lewin, G.: Ueber Morbus Addisonii Charitè Annalen 17: 536, 1892.Google Scholar
27. Meakin, J. T., Nelson, D. H. e Thorn, G. W.: Addison's disease in two brothers. J. Clin. Endocrinol. & Metab., 19: 726, 1959.Google Scholar
28. Medrei, H. W.: (citato da Weitz).Google Scholar
29. Mitchell, R. G. e Rhaney, K.: Congenital Adrenal Hypoplasia in siblings. Lancet, 1: 7071, 488, 1959.Google Scholar
30. Moehling, R. C.: Addison's disease followed for nine years: case report woth autopsy. J. Clin. Endocrinol. & Metab., 7: 134, 1947.CrossRefGoogle Scholar
31. Morabito, F.: Sul morbo di Addison e le sue forme fruste nell'infanzia. Pediatria, 35: 966, 1927.Google Scholar
32. Mozziconacci, P., L'Hiroudel, J., Girard, F. e Attal, G.: Maladie d'Addison familiale avec insufficience surrénale dissociée. Sem. Hop., 36: 1529, 1960.Google Scholar
33. Roberts, M. H. e Baehren, P. F.: Adrenocortical insufficency observed in three male infants in one family. J. Med. Ass. Georgia, 41: 299, 1952.Google Scholar
34. Rolleston, H.: The Endocrine organs in health and disease. Oxford Univers. Press, New York, N. Y., 1936.Google Scholar
35. Smith, T. W. e Higgins, A. R.: Addison's disease in two brothers with serum hepatitis in one. Military Surgeon, 110: 180, 1952.Google Scholar
36. Stoerk, O. e Epstein, E.: Ueber arterielle Gefassveranderungen bei Grippe. Frankf. Ztschr. f. Path., 23: 163, 1920.Google Scholar
37. Wakefield, E. G. e Smith, E. F.: Addison's disease, superrenalopathies and sclerosis of the glands of internal secretion. Clinical reports and review of the literature. Am. J. Med. Sci., 174: 342, 1927.Google Scholar
38. Weitz, K.: Die Vererbung inneren Krankheiten. Stuttgart, 1936.Google Scholar
39. Winter, E. S.: The suprarenales gland in influenza. Brit. Med. J., 2: 629, 1918.Google Scholar
40. Wolff, S.: Female pseudohermaphroditism with adrenocortical failure in identical twins. Arch. Dis. Child., 29: 132, 1954.Google Scholar
(I) Bierich, J. R., Bohe, E. e Voigt, K. D.: New aspects of the pathogenesis of the adrenogenital syndrome. Acta endocrinol., 18: 512, 1955.Google Scholar
(II) Broster, L. R., Patterson, J. e Camber, B.: Adrenal pseudohermaphroditism. Brit. Med. J., 4890: 1288, 1953.Google Scholar