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Human Ring Chromosome Syndromes: An “E” Ring Associated with an Abnormal Phenotype*

Published online by Cambridge University Press:  01 August 2014

Anil K. Sinha
Anil K. Sinha*
Affiliation:
Texas Children's Hospital, Houston, Texas

Summary

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In peripheral blood cultures of a phenotypically abnormal Caucasian girl, a ring-shaped chromosome was observed in place of an E group member. The rest of the chromosomes of the complement did not show any obvious structural anomaly. The ring chromosome was noted in 100% of the recorded cells, and its size in individual metaphases remained fairly constant. It is suggested that this ring chromosome has become a permanent part of the complement of the patient.

Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 17 , Issue 3 , July 1968 , pp. 487 - 494
Copyright
Copyright © The International Society for Twin Studies 1968

Footnotes

*

Supported in part by Baylor University College of Medicine General Research Grant (P-13) and grants from the James Picker Foundation and the Texas Heart Association. Harvey S. Rosenberg, M. D., Director of Laboratories, Texas Children's Hospital, has prepared the case history of the patient. Technical assistance was provided by Miss Marion Gay and Miss Shirley Powell. The editorial assistance of Miss Marilyn Morningstar is also acknowledged.

References

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