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Discordant Anencephaly in a Set of Triplets

Published online by Cambridge University Press:  01 August 2014

M.E. D'Alton ,
E.R. Newton  and
C.L. Cetrulo
M.E. D'Alton*
Affiliation:
Department of Maternal Fetal Medicine, Tufts University School of Medicine, and St. Margaret's Hospital for Women, Boston
E.R. Newton
Affiliation:
Department of Maternal Fetal Medicine, Tufts University School of Medicine, and St. Margaret's Hospital for Women, Boston
C.L. Cetrulo
Affiliation:
Department of Maternal Fetal Medicine, Tufts University School of Medicine, and St. Margaret's Hospital for Women, Boston
*
St. Margaret's Hospital, 90 Cushing Avenue, Boston, MA 02125, USA

Abstract

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A 38-year-old woman, gravida 5, para 3, with a triplet prgnancy discordant for anencephaly, is reported. The diagnosis was made prenatally by ultrasound. Autopsy of the anencephalic member revealed small adrenal glands with absent fetal cortex, and a coincidental tetralogy of Fallot. Studies of the histocompatible lymphocyte antigens of both parents were performed and they failed to demonstrate HLA B-27. The literature on anencephaly in triplets is summarized. The association of congenital heart disease and HLA B-27 with anencephaly is discussed.

Keywords

TripletsAnencephalyAdrenal hypoplasiaTetralogy of FallotHLA B-27
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 33 , Issue 1 , January 1984 , pp. 71 - 73
Copyright
Copyright © The International Society for Twin Studies 1984

References

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