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Developments in the Use of X-Rays in Body Composition Analysis

Published online by Cambridge University Press:  06 March 2019

L. E. Preuss  and
F. P. Bolin
L. E. Preuss
Affiliation:
Edsel B. Ford Institute for Medical Research 2799 West Grand Blvd. Detroit, MI 48202
F. P. Bolin
Affiliation:
Edsel B. Ford Institute for Medical Research 2799 West Grand Blvd. Detroit, MI 48202
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Extract

Quantitative assay of body components in the living human is a subject of keen interest. Measurement of such fractions on superficial view seems a simple analysis problem. In fact, the opposite is true. The ‘specimen’ is not amenable to the usual destructive analytical procedures. Due to its importance, a continued effort has been mounted to assay the most basic of such components. This paper and bibliography traces the recent applications of penetrating radiation for such analysis.

Some of the fractions whose measurement has been attempted are; bone mineral, adiposity (lipid to lean ratio), body hydration, tissue density, voids and spaces (i.e. lung). The importance of quantitative analysis of such gross components is apparent when taking mineralization as example.

Type
Research Article
Information
Advances in X-Ray Analysis , Volume 22: Twenty-Seventh Annual Conference on Applications of X-ray Analysis, August 1-4, 1978 , 1978 , pp. 419 - 424
Copyright
Copyright © International Centre for Diffraction Data 1978

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References

Bolin, F.P., Preuss, L.E., Glibert, K.M. and Bugenis, C.K. “Errors in Dual X-Ray Beam Differential Absorptiometry,” Advances in X-Ray Analysis (Plenum Press, NY 1978) Vol. 21 p 155.Google Scholar
Burch, W. and Bloch, P., “Two Wavelength Technique for the Measurement of Bone Mineral Content In Vivo,” Proceedings of Bone Measurement Conference, Conf. 700515, 263 (1970).Google Scholar
Cameron, J.R. and Sorenson, J.A., “Measurement of Bone Mineral In Vivo: an Improved Method,” Science, 142, 230 (1963).Google Scholar
Cameron, J.R. and Sorenson, J.A., “A Reliable Measurement of Bone Mineral Content In Vivo,” (Abst.) Journal of Nuclear Medicine 8 , 268 (1967).Google Scholar
Cameron, J.R., Mazess, R.B., and Sorenson, J.A., “Precision and Accuracy of Bone Mineral Determination by Direct Photon Absorptiometry,” AEC Report COO-1422-32, (1968).Google Scholar
Chan, J.L.H., Alvarez, R.E. and Macovski, A., “Measurement of Soft Tissue Overlying Bone Utilizing Broad Band Energy Spectrum Techniques,” Nuclear Science, NS-13, 551 (1976).Google Scholar
Clarke, R.L. and Van Dyk, G., “A New Method for Measurement of Bone Mineral Content Using both Transmitted and Scattered Beams of Gamma-Rays,” Physics in Medicine and Biology, 18, 532 (1973).Google Scholar
Demling, R.H., Mazess, R.B., Witt, R.M., and Wolberg, W.H., “The Study of Burn Wound Edema Using Dichromatic Absorptiometry,” Journal of Trauma 19 124 (1978).Google Scholar
Dohring, W., Reiss, K.H. and Fabel, H., “Compton Scatter for Local In Vivo Assessment of Density in the Lung,” Pneumonolgie 150, 345 (1974).Google Scholar
Evans, A.L., Davison, M., Kennedy, J., Shimmins, J.G., and Sutherland, G.R., “A Gamma Ray Densitometer for the Investigation of Pulmonary Function,” Physics in Medicine and Biology 20 261 (1975).Google Scholar
Farmer, F.T. and Collins, M.P., “A New Approach to the Determination of Anatomical Cross-Sections of the Body by Compton Scat tering of Gamma-Haya,” Physics in Medicine and Biology 16, 577 (1971).Google Scholar
Garnett, E.S., Kennett, T.J., Kenyon, D.B. and Webber, C.E., “A Photon Scattering Technique for the Measurement of Absolute Bone Density in Man,” Radiology 106, 209 (1973).Google Scholar
Garnett, E.S., Webber, C.E., Coates, G., Cockshott, W.P., Nahmias, C. and Lassen, N., “ Lung Density: Clinical Method for Quantitation of Pulmonary Congestion and Edema,” CMA Journal 116, 153 (1977).Google Scholar
Gershon-Cohen, J., Cherry, N.H. and Boehnke, M., “Bone Density Studies with a Gamma Gauge,” Radiation Research 8 , 509 (1958).Google Scholar
Gustafsson, L., Jacobson, B. and Kusoffsky, L., “X Ray Spectrophotometry for Bone-Mineral Determinations,” Medical and Biological Engineering p 113 (Jan 1974).Google Scholar
Hudepohl, R., Kedem, D., Price, R.R., Wagner, J. and Brill, A.B., “Three Photon Absorption Techniques,” Physics in Canada 32, 15.5 (1976).Google Scholar
Jacobson, B. and Bjorn, Lindberg, “X-Ray Spectrophotometer for Simultaneous Analysis of Several Elements,” Review of Scientific Instruments 35, 1316 (1964).Google Scholar
Judy, P.F., Cameron, J.R. and Vogel, J.M., “A Method to Estimate the Error Caused by Adipose Tissue in the Absorptiometric Measurement of Bone Mineral Mass,” AEC Report COO-1422-141 (1973).Google Scholar
Kairento, A.L. and Spring, E., “Measurement of Bone Mineral and Body Composition by the Attenuation of Three Low-Energy Radiations from 241Am,” Annals of Clinical Research 6 , 80 (1974).Google Scholar
Kan, W.C., Wilson, C.R., Witt, R.M. and Mazess, R.B., “Direct Readout of Bone Mineral Content with Dichromatic Absorptiometry,” International Conference on Bone Mineral Measurement, (NIH) 75–683 66 1973.Google Scholar
Kaufman, L., Gamsu, O., Savoca, C.H., and Swann, S., “Three Dimensional Lung Densitometer Using CdTe Detectors for Diagnosis and Evaluation of the Progress of Pulmonary Edema,” Revue de Physique Appliquee 12, 369 (1977).Google Scholar
Krokowski, E., “Calcium Determination in the Skeleton by Means of X-Ray Beams of Different Energies,” Symposium Ossium, Editors Jelliffe, A.M., and Strickland, B. (E&S Livingstone, Edinburgh and London, (1970) p 154.Google Scholar
Mazess, R.B., Cameron, J.R., Sorenson, J.A., “Determining Body Composition by Radiation Absorption Spectrometry, “Nature 228, 771 (1970).Google Scholar
Mazess, R.B., Cameron, J.R., O'Connor, R. and Knutzen, D., “Accuracy of Bone Mineral Measurement,” Science 145, 388 (1964).Google Scholar
Olkkonen, H., Puumalainen, P., Karjalainen, P., Alhava, E.M., “Measurement of Bone Mineral Density Using Coherent and Compton Scattering,” American Journal of Roentgenology, 126: 1279 (1976).Google Scholar
Pelc, N., “Body Composition Measurements Using 109cd,” AEC Report COO-1422-185 (1974).Google Scholar
Fiper, D.G., Preuss, L.E., “Absolute Bone Density Measurement Using Compton Scattered Radiation,” American Journal of Roentgenology, 126: 1279 (1976).Google Scholar
Preuss, L.E. and Schmonsees, W.G., “109Cd for Compositional Analysis of Soft Tissue,” International Journal of Applied Radiation and Isotopes, 24, 9 (1972).Google Scholar
Preuss, L.E. and Bolin, F.P., “in Vivo Analysis of Lipid-Protein Ratios in Human Muscle by Differential X-Ray Absorption Using 109Cd Photons,” Advances in X-Ray Analysis 16, 111 (1972).Google Scholar
Preuss, L.E. and Bolin, F.P., “In Vivo Tissue Analysis with 109cd,” Isotopes and Radiation Technology 9, 501 (1972).Google Scholar
Preuss, L.E. and Leachy, D.M., “Low-Energy Photons in the Life Sciences,” Proceedings of Symposium on Low-Energy X- and Gamma Sources and Applications, 0RNL-11C-10 Vol. 1, 197 (1965).Google Scholar
Price, R.R., Wagner, J., Larsen, K., Patton, J., Brill, A.E., “Regional and Whole-Body Bone Mineral Content Measurement with a Rectilinear Scanner,” American Journal of Roentgenology, 126: 1277 (1976).Google Scholar
Puumalainen, P., Olkkonen, H. and Sikanen, P., “Assessment of Fat Content of Liver by a Photon Scattering Technique,” International Journal of Applied Radiation and Isotopes 28, 785 (1977).Google Scholar
Reiss, K. H. and Steinle, B., “Medical Application of the Compton Effect,” Siemens Forsch.-Entwickl-Ber Bd. 2 (1973).Google Scholar
Reiss, K. H. and Schuster, W., “Quantitative Measurements of Lung Function in Children by Means of Compton Backscatter,” Radiology 102, 613 (1972).Google Scholar
Sandrik, J.M. and Judy, P.F., “Effects of the Polyenergetic Character of the Spectrum of 125j on the Measurement of Bone Mineral Content,” Investigative Radiology 8 , 143 (1973).Google Scholar
Waggener, R.G., Rogers, L.F. and Zanca, P., “A Polychromatic X-Ray Beam to Represent n Monoenergetic Photon Sources,” Proceedings of Bone Mineral Conference Conf, 700515, 314 (1970).Google Scholar
Watt, D.E., “Optimum Photon Energies for the Measurement of Bone Mineral and Fat Fractions,” British Journal of Radiology 48, 265 (1975).Google Scholar
Webber, C.E. and Kennett, T.J., “Bone Density Measured by Photon Scattering I. A System for Clinical Use,” Physics in Medicine and Biology, 21, 760 (1976).Google Scholar
Wilson, C.R., Cameron, J.R., Ritman, E.L., Sturm, E.R. and Robb, R.A., “Video-Roentgen Absorptiometry for the Measurement of Bone Mineral Mass,” AEC Report COO-1422-152 (1973).Google Scholar
Wooten, W.W., Judy, P.F. and Greenfield, M.A., “Analysts of the Effects of Adipose Tissue on the Absorptiometric Measurement of Bone Mineral Mass,” Investigative Radiology 8 , 84 (1973).Google Scholar
Zeitz, L., “Effect of Subcutaneous Fat on Bone Mineral Content Measurement, with the ‘Single-Energy’ Photon Absorptiometry Technique,” ACTA Radiologica 11, 401 (1972).Google Scholar
Zimmerman, R.E., Griffiths, H.J. and D'Orsi, C., “Bone Mineral Measurement by Means of Photon Absorption,“Radiology 106 561 (1973).Google Scholar