Overview

The concept that schizophrenia is a grouping of, rather than a single illness, is well accepted. However, it is seldom explored and rarely taken into account when investigating the disorder. This symposium is structured to give a snapshot of different concepts of endophenotypes, starting with those arising from basic research, progressing to an endophenotype associated with a purported risk factor for schizophrenia. We then move into the clinical setting, addressing whether or not testing paradigms define discrete groupings of altered functionality. The symposium ends with a presentation on endophenotypes defined by cognitive testing and the genetic aspect of such deficits.