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Chapter 23 - Ovarian reserve as a guide for ovarian stimulation

from Section 6: - Procedures before, during, and after ovarian stimulation

Published online by Cambridge University Press:  05 August 2011

By
Luciano G. Nardo  and
Lamiya Mohiyiddeen
Edited by
Mohamed Aboulghar  and
Botros Rizk
Mohamed Aboulghar
Affiliation:
Cairo University and the IVF-ET Center
Botros Rizk
Affiliation:
University of South Alabama
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Summary

This chapter discusses the methods currently used for the assessment of ovarian reserve and the prediction of ovarian response to stimulation. It highlights that even when using very low follicle stimulating hormone (FSH) levels the accuracy in the prediction of ovarian reserve is only modest, making it inferior to other markers currently used. Antral follicle count (AFC) was found to correlate with, but was superior to, biochemical markers such as basal estradiol (E2), inhibin B, and FSH in predicting ovarian responsiveness. The combination of markers has been proposed for a better estimate of functional gonadal capacity. Ovarian reserve tests have only modest predictive value, especially in the prediction of occurrence of pregnancy and live birth. More studies are needed to evaluate the use of anti-Mullerian hormone (AMH) in conjunction with AFC in the prediction of ovarian reserve and ovarian response.
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Ovarian Stimulation , pp. 255 - 261
Publisher: Cambridge University Press
Print publication year: 2010

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