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  3. Introduction to Computational Genomics
  • Cited by 14
Publisher:
Cambridge University Press
Online publication date:
June 2012
Print publication year:
2006
Online ISBN:
9780511808982
DOI:
https://doi.org/10.1017/CBO9780511808982
Subjects:
Computer Science, Computational Biology and Bioinformatics, Scientific Computing, Scientific Software
Information

Book description

Where did SARS come from? Have we inherited genes from Neanderthals? How do plants use their internal clock? The genomic revolution in biology enables us to answer such questions. But the revolution would have been impossible without the support of powerful computational and statistical methods that enable us to exploit genomic data. Many universities are introducing courses to train the next generation of bioinformaticians: biologists fluent in mathematics and computer science, and data analysts familiar with biology. This readable and entertaining book, based on successful taught courses, provides a roadmap to navigate entry to this field. It guides the reader through key achievements of bioinformatics, using a hands-on approach. Statistical sequence analysis, sequence alignment, hidden Markov models, gene and motif finding and more, are introduced in a rigorous yet accessible way. A companion website provides the reader with Matlab-related software tools for reproducing the steps demonstrated in the book.

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