Abraham, M.H., Hassanisadi, M., Jalali-Heravi, M., Ghafourian, T., Cain, W.S. and Cometto-Muniz, J.E. 2003. Draize rabbit eye test compatibility with eye irritation thresholds in humans: a quantitative structure-activity relationship analysis. Toxicological Sciences 76: 384–391.
Adams, R. 1977. The Plague Dogs. Harmondsworth: Penguin.
Akhtar, A. 2015. The flaws and human harms of animal experimentation. Cambridge Quarterly of Healthcare Ethics 24: 407–419.
American Medical Association Council on Scientific Affairs 1989. Council report on animals in research. Journal of the American Medical Association 261: 3602–3606.
Animal Welfare Committee 2007. National Health and Medical Research Council Guidelines for the Generation, Breeding, Care, and Use of Genetically Modified and Cloned Animals for Scientific Purposes. Canberra: Australian Government.
Anon. 1992. Scientific procedures on living animals, cited in Porter, D.G. Ethical scores for animal experiments. Nature 356: 101–102.
Ashall, V. and Millar, K. 2014. Endpoint matrix: a conceptual tool to promote consideration of the multiple dimensions of humane endpoints. Alternatives to Animal Experimentation 31: 209–213.
Association for the Study of Animal Behaviour 2012. Guidelines for the treatment of animals in behavioural research and teaching. Animal Behaviour 83: 301–309.
Australian Government, Senate Select Committee on Animal Welfare 1989. Animal Experimentation. Canberra: Australian Government Publishing Service.
Bacon, F. 1605/2001. The Advancement of Learning (1605), Gould, S.J. (ed.). New York: Random House.
Bailey, K.R., Rustay, N.R. and Crawley, J.N. 2006. Behavioral phenotyping of transgenic and knockout mice: practical concerns and potential pitfalls. ILAR Journal 47: 124–131.
Baker, K.C. and Dettmer, A.M. 2016. The well-being of laboratory non-human primates. American Journal of Primatology doi:10.1002/ajp.22520.
Balcombe, J.P., Barnard, N.D. and Sandusky, C. 2004. Laboratory routines cause animal stress. Journal of the American Association for Laboratory Animal Science 43: 42–51.
Balls, M. 1990. Recent progress toward reducing the use of animal experimentation in biomedical research. In Garattini, S. and van Bekkum, D.W. (eds.), The Importance of Animal Experimentation for Safety and Biomedical Research, pp. 223–235. Dordrecht: Kluwer.
Battye, J. 1994. Ethics and animal welfare - where do we go from here? In Baker, R.M., Mellor, D.J. and Nicol, A.M. (eds.) Animal Welfare in the Twenty-First Century: Ethical, Educational and Scientific Challenges, pp. 3–10. Adelaide: ANZCCART.
Baumans, V., Coke, C., Green, J., Moreau, E., Morton, D., Patterson-Kane, E., Reinhardt, A., Reinhardt, V. and Van Loo, P. (eds.) 2007. Making Lives Easier for Animals in Research Labs. Washington DC: Animal Welfare Institute. www.awionline.org/pubs/LAREF/LAREF-bk.html
Bayne, K. and Würbel, H. 2014. The impact of environmental enrichment on the outcome variability and scientific validity of laboratory animal studies. Scientific and Technical Review of the Office International des Epizooties (Paris) 33: 273–280.
Bayne, K., Ramachandra, G.S., Rivera, E.A. and Wang, J. 2015. The evolution of animal welfare and the 3Rs in Brazil, China, and India. Journal of the American Association for Laboratory Animal Science 54: 181–191.
Behrens, K.G. 2014. Genetic modification (GMOs): Animals. In ten Have, H. (ed.) Encyclopedia of Global Bioethics, pp. 1–10. doi:10.1007/978-3-319-05544-2_209-1.
Bekoff, M. (ed.) 2013. Ignoring Nature No More: The Case for Compassionate Conservation. Chicago: University of Chicago Press.
Benassi, L., Bertazzoni, G. and Seidenari, S. 1999. In vitro testing of tensides employing monolayer cultures: a comparison with results of patch tests on human volunteers. Contact Dermatitis 40: 38–44.
Benison, S. 1970. In defense of medical research. Harvard Medical, Alumni Bulletin 44: 16–23.
Bentham, J. 1789/1970. An introduction to the principles of morals and legislation. In Burns, J.H. and Hart, H.L.A. (eds.), The Collected Works of Jeremy Bentham, Vol. 2.1. London: Athlone.
Bernard, C. 1865/1957. An Introduction to the Study of Experimental Medicine, trans. Greene, H.C., 1957. New York: Dover.
Bilbo, S.D. and Nelson, R.J. 2001. Behavioral phenotyping of transgenic and knockout animals: a cautionary tale. Lab Animal 30: 24–29.
Birch, C. 1993. Regaining Compassion for Humanity and Nature. Kensington: New South Wales University Press, pp. 86–96.
Bliss, M. 1982. The Discovery of Insulin. Chicago: University of Chicago Press.
Brabazon, J. 1976. Albert Schweitzer: A Biography. London: Victor Gollancz.
Britt, D. 1984. Ethics, ethical committees and animal experimentation. Nature 311: 503–506.
Bronowski, J. 1956. Science and Human Values, revised edition 1965. New York: Harper and Row.
Brown, M.J. and Murray, K.A. 2006. Phenotyping of genetically engineered mice: humane, ethical, environmental, and husbandry issues. ILAR Journal 47: 118–123.
Bruce, D. and Bruce, A. 2003. Genetic engineering and animal welfare. In Armstrong, S.J. and Botzler, R.G. (eds.), The Animal Ethics Reader, pp. 313–322. London: Routledge.
Buehr, M., Hjorth, J.P. and Hansen, A.K. 2003. Genetically modified laboratory animals – what welfare problems do they face? Journal of Applied Animal Welfare Science 6: 319–338.
Burden, N., Sewell, F. and Chapman, K. 2015. Testing chemical safety: what is needed to ensure the widespread application of non-animal approaches? PLOS Biology 13(5) e1002156. doi:10.1371/journal.pbio.1002156.
Calisi, R.M. and Bentley, G.E. 2009. Lab and field experiments: are they the same animal? Hormones and Behavior 56: 1–10.
Callicott, J.B. 1989. In Defense of the Land Ethic: Essays in Environmental Philosophy. New York: State University of New York Press.
Caplan, A. 1989. Cited in Animal Experimentation, Australian Government, Senate Select Committee on Animal Welfare. Canberra: Australian Government Publishing Service.
CIOMS and ICLAS, Council for International Organizations of Medical Sciences (CIOMS), International Council for Laboratory Animal Science (ICLAS) 2012. International Guiding Principles for Biomedical Research Involving Animals. www.cioms.ch.
Clark, S.R.L. 1984. The Moral Status of Animals. Oxford: Oxford University Press.
Clark, S.R.L. 1997. Animals and Their Moral Standing. London: Routledge.
Cloutier, S., Panksepp, J. and Newberry, R.C. 2012. Playful handling by caretakers reduces fear of humans in the laboratory rat. Applied Animal Behaviour Science 140: 161–171.
Cordelli, E., Fresegna, A.M., D’Alessio, A., Spano, M., Villani, P. and Pacchierotti, F. 2007. A new in vitro method to assess DNA damage in sperm as an alternative to animal testing in reproductive toxicology. Toxicology Letters 172: S76. doi:10.1016/j.toxlet.2007.05.218.
Cottingham, J. 1978. A brute to the brutes?: Descartes’ treatment of animals. Philosophy 53: 551–559.
Cranefield, P.F. 1974. The Way In and the Way Out: François Magendie, Charles Bell, and the Roots of the Spinal Nerves. New York: Futura.
Cressey, D. 2011. Animal research: battle scars. Nature 470: 452–453.
Crettaz von Roten, F. 2012. Public perceptions of animal experimentation across Europe. Public Understanding of Science 22: 691–703.
Curtright, A., Rosser, M., Goh, S. Keown, B., Wagner, E., Sharifi, J., Raible, D.W. and Dhaka, A. 2015. Modeling nociception in zebrafish: a way forward for unbiased analgesic discovery. PloS One 10(1): e0116766. doi:10.1371/journal.pone.0116766.
Daneshian, M., Busquet, F., Hartung, T. and Leist, M. 2015. Animal use for science in Europe. Alternatives to Animal Experimentation 32: 261–274.
Darwin, C. 1859/2009. On the Origin of Species by Natural Selection. New York: Oxford University Press.
Darwin, C. 1871/2004. The Descent of Man, and Selection in Relation to Sex. London: Penguin Classics.
Darwin, C. 1881/1985. The Formation of Vegetable Mould, through the Action of Worms. Facsimile of the first edition reprinted by the University of Chicago Press, Chicago.
Daston, G., Knight, D.J., Schwarz, M., Gocht, T., Thomas, R.S., Mahony, C. and Whelan, M. 2015. SEURAT: Safety evaluation ultimately replacing animal testing – recommendations for future research in the field of predictive toxicology. Archives of Toxicology 89: 15–23.
Davies, J. (ed.) 2012a. Replacing Animal Models: A Practical Guide to Creating and Using Culture-based Biomimetic Alternatives. Hoboken, NJ: John Wiley.
Davies, J. 2012b. Potential advantages of using biomimetic alternatives. In Davies, J. (ed.) Replacing Animal Models: A Practical Guide to Creating and Using Culture-based Biomimetic Alternatives, pp. 3–11. Hoboken, NJ: John Wiley.
Denton, D. 1993. The Pinnacle of Life: Consciousness and Self-Awareness in Humans and Animals. Sydney: Allen and Unwin.
Descartes, R. 1637/1984. Discours de la Méthode, trans. Curtis, D. London: Grant and Cutler.
Dewhurst, D. 2008. Is it possible to meet the learning objectives of undergraduate pharmacology classes with non-animal models? Alternatives to Animal Testing and Experimentation 14: 207–212.
Di Marco, P.N., Howell, J.McC. and Dorling, P.R. 1984. Bovine glycogenosis type II. Biochemical and morphological characteristics of skeletal muscle in culture. Neuropathology and Applied Neurobiology 10: 379–395.
Draize, J.H., Woodward, G. and Calvery, H.O. 1944. Methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membranes. Journal of Pharmacology and Experimental Therapy 82: 377–390.
Duckworth, W.L.H., Lyons, M.C. and Towers, B. (eds.) 1962. Galen, On Anatomical Procedures: The Later Books. Cambridge: Cambridge University Press.
Eisemann, C.H., Jorgensen, W.K., Merritt, D.J., Rice, M.J., Cribb, B.W., Webb, P.D. and Zalucki, M.P. 1984. Do insects feel pain? - A biological view. Experientia 40: 164–167.
Elwood, R.W. 2011. Pain and suffering in invertebrates? ILAR Journal 52: 175–184.
Enders, J.F., Weller, T.H. and Robbins, F.C. 1949. Cultivation of the Lansing strain of poliomyelitis virus in cultures of various human embryonic tissue. Science 109: 85–87.
European Commission 2009. EC Regulation No 1223/2009 of the European Parliament and of the Council of 30 November 2009 on cosmetic products. In Official Journal of the European Union. Brussels: EC, 2009, pp. 52–59.
European Commission 2010. Directive 2010/63/EU of the European Parliament and of the Council of 22 September 2010 on the protection of animals used for scientific purposes. In Official Journal of the European Union. Brussels: EC, 2010, pp. 33–79.
Feng, W., Dai, Y., Mou, L., Cooper, D.K.C., Shi, D. and Cai, Z. 2015. The potential of the combination of CRISPR/Cas9 and pluripotent stem cells to provide human organs from chimaeric pigs. International Journal of Molecular Science 16: 6545–6556.
Fisher, J.A. 1987. Taking sympathy seriously: a defense of our moral psychology toward animals. Environmental Ethics 9: 197–215.
Fleetwood, G., Chlebus, M., Coenen, J., Dudoignon, N., Lecerf, C., Maisonneuve, C. and Robinson, S. 2015. Making progress and gaining momentum in global 3Rs efforts: how the European pharmaceutical industry is contributing. Journal of the American Association for Laboratory Animal Science 54: 192–197.
Flemming, A.H. 1984. Ethical Considerations, cited in US Congress, Office of Technology Assessment, 1986, Alternatives to Animal Use in Research, Testing, and Education, p. 74. New York: Marcel Dekker.
Flexner, S. and Lewis, P.A. 1909. The transmission of acute poliomyelitis to monkeys. Journal of the American Medical Association 53(20): 1639. doi:10.1001/jama.1909.92550200027002g.
FRAME Toxicity Committee 1991. Animals and alternatives in toxicology: present status and future prospects. Alternatives to Laboratory Animals 19: 116–138.
Franco, N.H. 2013. Animal experiments in biomedical research: a historical perspective. Animals 3: 238–273.
Franco, N.H. and Olsson, I.A.S. 2014. Scientists and the 3Rs: attitudes to animal use in biomedical research and the effect of mandatory training in laboratory animal science. Laboratory Animals 48: 50–60.
Franco, N.H., Correia-Neves, M. and Olsson, I.A.S. 2012. How “humane” is your endpoint?—Refining the science-driven approach for termination of animal studies of chronic infection. PLoS Pathogens 8(1): e1002399. doi:10.1371/journal.ppat.1002399.
Franklin, A. 2007. Human-nonhuman animal relationships in Australia: an overview of results from the first national survey and follow-up case studies 2000–2004. Society and Animals 15: 7–27.
French, R.D. 1975. Antivivisection and Medical Science in Victorian Society. Princeton, NJ: Princeton University Press.
French, R.D. 1978. Animal experimentation: historical aspects. In Reich, W.T. (ed.), Encyclopedia of Bioethics, Vol. 1, pp. 75–79. New York: Free Press.
French, R.D. 1999. Dissection and Vivisection in the European Renaissance. Aldershot, UK: Ashgate Publishing.
Galen, , 1956. On Anatomical Procedures, trans. Singer, C. Oxford: Oxford University Press.
Galvin, S.L. and Herzog, H.A. 1998. Attitudes and dispositional optimism of animal rights demonstrators. Society and Animals 6: 1–11.
Gärtner, K., Büttner, D., Döhler, K., Friedel, R., Lindena, J. and Trautschold, I. 1980. Stress response of rats to handling and experimental procedures. Laboratory Animals 14: 267–274.
Gaughen, S. (ed.) 2005. Animal Rights: Contemporary Issues Companion. Farmington Hills, MI: Greenhaven Press.
Gauthier, C. and Griffin, G. 2005. Using animals in research, testing and teaching. Scientific and Technical Review of the Office International des Epizooties 24: 735–745.
Gerner, I., Liebsch, M. and Spielmann, H. 2005. Assessment of the eye irritating properties of chemicals by applying alternatives to the Draize rabbit eye test: the use of QSARs and in vitro tests for the classification of eye irritation. Alternatives to Laboratory Animals 33: 215–237.
Goodman, J.R. and Sanders, C.R. 2011. In favor of tipping the balance: animal rights activists in defense of residential picketing. Society and Animals 19: 137–155.
Gott, M. and Monamy, V. 2004. Ethics and transgenesis: towards a policy framework incorporating intrinsic objections and societal perceptions. Alternative to Laboratory Animals 32, Supplement 1A: 391–396.
Graham, D.M. 2016. Methods for measuring pain in laboratory animals. Lab Animal 45: 99–101.
Grant, L., Hopkinson, P., Jennings, G. and Jenner, F.A. 1971. Period of adjustment of rats used for experimental studies. Nature 232: 135.
Gray, G.E., Laher, F., Lazarus, E., Ensoli, B. and Corey, L. 2016. Approaches to preventative and therapeutic HIV vaccines. Current Opinion in Virology 17: 104–109.
Gross, D. and Tolba, R.H. 2015. Ethics in animal-based research. European Surgical Research 55: 43–57.
Gruen, L. 1991. Animals. In Singer, P. (ed.), A Companion to Ethics, pp. 343–353. Oxford: Blackwell Reference.
Gruen, L. 2011. Ethics and Animals: An Introduction. New York: Cambridge University Press.
Guillén, J., Prins, J.B., Smith, D. and Degryse, A.D. 2014. The European framework on research animal welfare regulations and guidelines. In Guillén, J. (ed.), Laboratory Animals: Regulations and Recommendations for Global Collaborative Research, pp. 117–188. New York: Elsevier.
Hakkinen, P.J. and Green, D.K. 2002. Alternatives to animal testing: information resources via the internet and world wide web. Toxicology 173: 3–11.
Harmon, T.M., Fisher, K.A., McGlynn, M.G., Stover, J., Warren, M.J., Teng, Y. and Näveke, A. 2016. Exploring the potential health impact and cost-effectiveness of AIDS vaccine within a comprehensive HIV/AIDS response in low- and middle-income countries. PLoS ONE 11(1): e0146387. doi:10.1371/journal.pone.0146387.
Hartung, T. 2011. From alternative methods to a new toxicology. European Journal of Pharmaceutics and Biopharmaceutics 77: 338–349.
Harvey, W. 1628/1978. Exercitatio anatomica de motu cordis et sanguinis in animalibus: being a facsimile of the 1628 Francofurti edition, together with the Keynes English translation of 1928. Birmingham, AL: Classics of Medicine Library.
Hodgson, J.C. and Koh, L.P. 2016. Best practice for minimising unmanned aerial vehicle disturbance to wildlife in biological field research. Current Biology 26: R404-R405 doi:10.1016/j.cub.2016.04.001.
Hoggatt, J., Hoggatt, A.F., Tate, T.A., Fortman, J. and Pelus, L.M. 2016. Bleeding the laboratory mouse: not all methods are equal. Experimental Hematology 44: 132–137.
Hooijmans, C.R., Tillema, A., Leenaars, M. and Ritskes-Hoitinga, M. 2010. Enhancing search efficiency by means of a search filter for finding all studies on animal experimentation in PubMed. Laboratory Animals 44: 170–175.
Howell, J.McC., Dorling, P.R. and Cook, R.D. 1983. Generalized glycogenosis type II. Comparative Pathology Bulletin 15: 2–4.
Hubrecht, R.C. 2014. The Welfare of Animals Used in Research: Practice and Ethics. Oxford: Wiley-Blackwell.
Hubrecht, R.C. and Kirkwood, J. (eds.) 2010. The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals, eighth edition. Hoboken, NJ: Wiley-Blackwell.
Hume, C.W. 1962. Man and Beast. London: Universities Federation for Animal Welfare.
Humphrey, N.K. 1983. Consciousness Regained: Chapters in the Development of Mind. Oxford: Oxford University Press.
Infield, L. 1963. Immanuel Kant: Lectures on Ethics. New York: Harper and Row.
Jackson, S.J., Andrews, N., Ball, D., Bellantuono, I., Gray, J., Hachoumi, L., Holmes, A., Latcham, J., Petrie, A., Potter, P., Rice, A., Ritchie, A., Stewart, M., Strepka, C., Yeoman, M. and Chapman, K. 2016. Does age matter? The impact of rodent age on study outcomes. Laboratory Animals doi:10.1177/0023677216653984.
Joffe, A.R., Bara, M., Anton, N. and Nobis, N. 2016. The ethics of animal research: a survey of the public and scientists in North America. BMC Medical Ethics 17: 17 doi:10.1186/s12910-016-0100-x.
Jung, K., Lee, S., Jang, W., Jung, H., Heo, Y., Park, Y., Bae, S., Lim, K. and Seok, S. 2014. KeraSkinTM_VM: a novel reconstructed human epidermis model for skin irritation tests. Toxicology in Vitro 28: 742–750.
Kar, S. and Roy, K. 2014. Quantification of contributions of molecular fragments for eye irritation of organic chemicals using QSAR study. Computers in Biology and Medicine 48: 102–108.
Kew, O. 2012. Reaching the last one per cent: progress and challenges in global polio eradication. Current Opinion in Virology 2: 188–198.
Kilkenny, C., Browne, W.J., Cuthill, I.C., Emerson, M. and Altman, D.G. 2010. Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research. PloS Biology 8(6): e1000412. doi:10.1371/journal.pbio.1000412.
Kilkenny, C., Parsons, N., Kadyszewski, E., Festing, M.F.W., Cuthill, I.C., Fry, D., Hutton, J. and Altman, D.G. 2009. Survey of the quality of experimental design, statistical analysis and reporting of research using animals. PloS One 4(11): e7824. doi:10.1371/journal.pone.0007824.
Kitchell, R.L. and Erickson, H.H. 1983. Introduction. In Kitchell, R.L. and Erickson, H.H. (eds.), Animal Pain: Perception and Alleviation, p. vii. Bethesda: American Physiological Society.
Knight, A. 2007. The effectiveness of humane teaching methods in veterinary education. Alternatives to Animal Testing and Experimentation 24: 91–109.
Knight, A. 2008. 127 million non-human vertebrates used worldwide for scientific purposes in 2005. Alternatives to Laboratory Animals 36: 494–496.
Knight, A. 2011. The Costs and Benefits of Animal Experiments. Basingstoke, UK: Palgrave MacMillan.
Lairmore, M.D. and Ilkiw, J. 2015. Animals used in research and education, 1966–2016: evolving attitudes, policies, and relationships. Journal of Veterinary Medical Education 42: 425–440.
Langley, G. 1989. Plea for a sensitive science. In Langley, G. (ed.), Animal Experimentation: The Consensus Changes, pp. 193–218. Oxford: MacMillan Press.
Lappin, G., Noveck, R. and Burt, T. 2013. Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology 9: 817–834.
Leahman, J., Latter, J. and Clemence, M. 2014. Attitudes to Animal Research in 2014: A Report by Ipsos MORI for the Department for Business Innovation and Skills. London: Ipsos MORI, Social Research Institute.
Lederer, S.E. 1987. The controversy over animal experimentation in America, 1880–1914. In Rupke, N.A. (ed.), Vivisection in Historical Perspective, pp. 236–258. London: Croom Helm.
Leopold, A. 1949. A Sand County Almanac. Oxford: Oxford University Press.
Lindsjö, J., Fahlman, A. and Törnqvist, E. 2016. Animal welfare from mouse to moose – implementing the principles of the 3Rs in wildlife research. Journal of Wildlife Diseases 52(2) Suppl.: S65-S77 doi:10.7589/52.2S.S65.
Linzey, A. 1989. Reverence, responsibility and rights. In Paterson, D. and Palmer, M. (eds.), The Status of Animals: Ethics, Education and Welfare, pp. 20–50. Oxford: CABI.
Linzey, A. and Clarke, P.A.B. 2004. Animal Rights: A Historical Anthology. Irvington, NY: Columbia University Press.
Littin, K.E. 2010. Animal welfare and pest control: meeting both conservation and animal welfare goals. Animal Welfare 19: 171–176.
Maehle, A-H. and Tröhler, U. 1987. Animal experimentation from antiquity to the end of the eighteenth century: attitudes and arguments. In Rupke, N.A. (ed.), Vivisection in Historical Perspective, pp. 14–47. London: Croom-Helm.
Manning, H. 1887/1934. Cardinal Manning, Archbishop of Westminster on Vivisection. London: Victoria Street Society for the Protection of Animals from Vivisection. Republished Melbourne.
Mather, J.A. 2011. Philosophical background of attitudes toward and treatment of invertebrates. ILAR Journal 52: 205–212.
Medina, L.V., Coenen, J. and Kastello, M.D. 2015. Global 3Rs efforts – making progress and gaining momentum. Journal of the American Association for Laboratory Animal Science 54: 115–118.
Mellor, D.J. 2015a. Positive animal welfare states and encouraging environment-focused and animal-to-animal interactive behaviours. New Zealand Veterinary Journal 63: 9–16.
Mellor, D.J. 2015b. Positive animal welfare states and reference standards for welfare assessment. New Zealand Veterinary Journal 63: 17–23.
Mellor, D.J. 2016. Updating animal welfare thinking: moving beyond the “five freedoms” towards “a life worth living.” Animals 6: 21. doi:10.3390/ani6030021.
Mellor, D., Patterson-Kane, K. and Stafford, K.J. 2009. The Sciences of Animal Welfare. Oxford: Wiley-Blackwell.
Miles, A., Berthet, A., Hopf, N.B., Gilliet, M., Raffoul, W., Vernez, D. and Spring, P. 2014. A new alternative method for testing skin irritation using a human skin model: a pilot study. Toxicology in Vitro 28: 240–247.
Mitchell, A. 2001. How to measure welfare of transgenic farm animals. Proceedings of a workshop, The Welfare of Transgenic Animals, p. 20. Adelaide: ANZCCART.
Moberg, G.P. 2000. Biological response to stress: implications for animal welfare. In Moberg, G.P. and Mench, J.A. (eds.), The Biology of Animal Stress: Basic Principles and Implications for Animal Welfare, pp. 1–22. Wallingford, UK: CAB International.
Monamy, V. 2007. Hot iron branding of seals and sea lions: why the ban will remain. Australian Veterinary Journal 85: 485–486.
Monamy, V. and Gott, M. 2001. Practical and ethical considerations for students conducting ecological research involving wildlife. Austral Ecology 26: 293–300.
Morton, D.B. 2000. A systematic approach for establishing humane endpoints. ILAR Journal 41: 80–86.
Morton, D.B. and Griffiths, P.H.M. 1985. Guidelines on the recognition of pain, distress and discomfort in experimental animals and an hypothesis for assessment. Veterinary Record 116: 431–436.
Mukerjee, M. 1997. Trends in animal research. Scientific American 276: 86–93.
Nash, R.F. 1990. The Rights of Nature. Sydney: Primavera Press.
National Centre for the Replacement Refinement and Reduction of Animals in Research 2006. NC3Rs Guidelines: Non-Human Primate Accommodation, Care and Use. London: National Centre for the Replacement, Refinement and Reduction of Animals in Research. www.nc3rs.org.uk/non-human-primate-accommodation-care-and-use.
National Health and Medical Research Council 1990. Strategies for Minimising the Numbers of Animals used in Research Projects. Canberra: Australian Government Printer.
National Health and Medical Research Council 2013. Australian Code for the Care and Use of Animals for Scientific Purposes, eighth edition. Canberra: National Health and Medical Research Council.
National Research Council 1985. Models for Biomedical Research: A New Perspective. Washington DC: National Academy Press.
National Research Council 1988. Use of Laboratory Animals in Biomedical and Behavioral Research. Washington DC: National Academy Press.
National Research Council 2007. Toxicity Testing in the 21st Century: A Vision and a Strategy. Washington DC: National Academies Press.
National Research Council 2008. Recognition and Alleviation of Distress in Laboratory Animals. Washington DC: National Academies Press.
National Research Council 2011. Guide for the Care and Use of Laboratory Animals, eighth edition, Washington DC: National Academies Press.
Nuffield Council on Bioethics 2016. Genome Editing: An Ethical Review. London: Nuffield Council on Bioethics.
OECD 2012. Fish Toxicity Testing Framework. OECD Series on Testing and Assessment, No. 171 ENV/JM/MONO(2012)16. Paris: Organisation for Economic Cooperation and Development.
Orlans, F.B. 1993. In the Name of Science: Issues in Responsible Animal Experimentation. New York: Oxford University Press.
Ormandy, E.H. and Schuppli, C.A. 2014. Public attitudes toward animal research: a review. Animals 4: 391–408.
Ormandy, E.H., Dale, J. and Griffin, G. 2011. Genetic engineering of animals: ethical issues, including welfare concerns. Canadian Veterinary Journal 52: 544–550.
Ormandy, E.H., Schuppli, C.A. and Weary, D.M. 2012. Factors affecting people’s acceptance of the use of zebrafish and mice in research. Alternatives to Laboratory Animals 40: 321–333.
Osterrieder, S.K., Kent, C.S., Anderson, C.J.R., Parnum, I.M. and Robinson, R.W. 2015. Whisker spot patterns: a noninvasive method of individual identification of Australian sea lions (Neophoca cinerea). Journal of Mammalogy 96: 988–997.
Parker, R.M.A. and Browne, W.J. 2014. The place of experimental design and statistics in the 3Rs. ILAR Journal 55: 477–485.
Paton, W.D.M. 1993. Man and Mouse: Animals in Medical Research, second edition. Oxford: Oxford University Press.
Paul, E., Sikes, R.S., Beaupre, S.J. and Wingfield, J.C. 2015. Animal welfare policy: implementation in the context of wildlife research – policy review and discussion of fundamental issues. ILAR Journal 56: 312–334.
Perry, P. 2007. The ethics of animal research: a UK perspective. ILAR Journal 48: 42–46.
Phillips, M.T. and Sechzer, J.A. 1989. Animal Research and Ethical Conflict: An Analysis of the Scientific Literature 1966–1986. New York: Springer-Verlag.
Pifer, L., Shimizu, K. and Pifer, R. 1994. Public attitudes toward animal research: some international comparisons. Society and Animals 2: 95–113.
Plint, A.C., Moher, D., Morrison, A., Schulz, K., Altman, D.G., Hill, C. and Gaboury, I. 2006. Does the CONSORT checklist improve the quality of reports of randomised controlled trials? A systematic review. Medical Journal of Australia 185: 263–267.
Poling, A., Schlinger, H., Starin, S. and Blakely, E. 1990. Psychology: A Behavioral Overview. New York: Plenum Press.
Porter, D.G. 1992. Ethical scores for animal experiments. Nature 356: 101–102.
Poumay, Y. and Coquette, A. 2007. Modelling the human epidermis in vitro: tools for basic and applied research. Archives of Dermatological Research 298: 361–369.
Regan, T. 1981. Animal rights and animal experimentation. In Basson, M.D. (ed.), Rights and Responsibilities in Modern Medicine, pp. 69–83. New York: Alan R. Liss.
Regan, T. 1982. All That Dwell Therein: Animal Rights and Environmental Ethics. Berkeley: University of California Press.
Regan, T. 1983. The Case for Animal Rights. Berkeley: University of California Press.
Regan, T. 1985. The case for animal rights. In Singer, P. (ed.), In Defense of Animals, pp. 13–26. Oxford: Basil Blackwell.
Regan, T. 1990. The struggle for animal rights. In Clarke, P.A.B. and Linzey, A. (eds.), Political Theory and Animal Rights, pp. 176–186. London: Pluto Press.
Regan, T. and Singer, P. (eds.) 1976. Animal Rights and Human Obligations. Englewood Cliffs, NJ: Prentice-Hall.
Remfry, J. 1987. Ethical aspects of animal experimentation. In Tuffery, A.A. (ed.), Laboratory Animals: An Introduction for New Experimenters, pp. 5–19. Chichester: John Wiley and Sons.
Riordan, S.M., Heruth, D.P., Zhang, L.Q. and Ye, S.Q. 2015. Application of CRISPR/Cas9 for biomedical discoveries. Cell & Bioscience 5: 33. doi:10.1186/s13578-015-0027-9.
Rodd, R. 1990. Biology, Ethics and Animals. Oxford: Clarendon Press.
Rollin, B.E. 1981. Animal Rights and Human Morality. New York: Prometheus.
Rolston, H. 1988. Environmental Ethics: Duties to and Values in the Natural World. Philadelphia: Temple University Press.
Rose, M. and Adams, D. 1989. Evidence for pain and suffering in other animals. In Langley, G. (ed.), Animal Experimentation: The Consensus Changes, pp. 42–71. Oxford: MacMillan Press.
Rosenfield, L.C. 1940. From Beast-Machine to Man-Machine. Oxford: Oxford University Press.
Rossi, J. 2015. Research: animals. Encyclopedia of Global Bioethics doi:10.1007/978-3-319-05544-2_373-1.
Rothschild, M. 1986. Animals and Man. The Romanes Lecture for 1984–85. Oxford: Clarendon Press.
Rowan, A.N. 1984. Of Mice, Models and Men: A Critical Evaluation of Animal Research. Albany, NY: State University of New York Press.
Rowan, A.N. and Rollin, B.E. 1983. Animal research - for and against: a philosophical, social, and historical perspective. Perspectives in Biology and Medicine 27: 1–17.
RSPCA and LASA 2015. Guiding Principles on Good Practice for Animal Welfare and Ethical Review Bodies. A report by the RSPCA Research Animals Department and LASA Education, Training and Ethics Section. (Jennings, M., ed.).
Rubin, S.A. 2011. Toward replacement of the monkey neurovirulence test in vaccine safety testing. Procedia in Vaccinology 5: 261–265.
Rupke, N.A. 1987. Introduction. In Rupke, N.A. (ed.), Vivisection in Historical Perspective, pp. 1–13. London: Croom-Helm.
Russell, W.M.S. and Burch, R.L. 1959/1992. The Principles of Humane Experimental Technique. London: UFAW.
Rutherford, K.M.D. 2002. Assessing pain in animals. Animal Welfare 11: 31–53.
Ryder, R.D. 1975. Victims of Science: The Use of Animals in Research. London: Davis-Poynter.
Ryder, R.D. 2000. Animal Revolution: Changing Attitudes towards Speciesism, second edition. Oxford: Berg Publishers.
Sagan, C. and Druyan, A. 1992. Shadows of Forgotten Ancestors: A Search for Who We Are. Sydney: Random House.
Schweitzer, A. 1936. Indian Thought and Its Development. London: Adam and Charles Black.
Schweitzer, A. 1955. Civilization and Ethics, third edition. London: Adam and Charles Black.
Schweitzer, A. 1966. My Life and Thought: An Autobiography. London: Unwin Books.
Selye, H. 1975. The Stress of Life, second edition. New York: McGraw-Hill.
Selye, H. 1976. Stress in Health and Disease. Boston: Butterworths.
Seruggia, D. and Montoliu, L. 2014. The new CRISPR-Cas system: RNA-guided genome engineering to efficiently produce any desired genetic alteration in animals. Transgenic Research 23: 707–716.
Seyfarth, R. M., Cheney, D. L. and Marler, P. 1980. Monkey responses to three different alarm calls: evidence of predator classification and semantic communication. Science 210: 801–803.
Shaw, G.B. 1912. The Uselessness of the Vivisection Inspector. London: British Union for the Abolition of Vivisection.
Shugg, W. 1968a. Humanitarian attitudes in the early animal experiments of the royal society. Annals of Science 24: 227–238.
Shugg, W. 1968b. The Cartesian beast-machine in English literature (1663–1750). Journal of the History of Ideas 29: 279–292.
Sikes, R.S. and Bryan, J.A. II. 2015. Institutional animal care and use committee considerations for the use of wildlife in research and education. ILAR Journal 56: 335–341.
Sikes, R.S. and the Animal Care and Use Committee of the American Society of Mammalogists 2016. 2016 guidelines of the American Society of Mammalogists for the use of wild mammals in research and education. Journal of Mammalogy 97: 663–688.
Singer, C.J. 1957. A Short History of Anatomy from the Greeks to Harvey, second edition. New York: Dover Publications.
Singer, P. 1975. Animal Liberation. New York: Avon Books.
Singer, P. 1978. Animal experimentation: philosophical perspectives. In Reich, W.T. (ed.), Encyclopedia of Bioethics, Vol. 1, pp. 79–83. New York: Free Press.
Singer, P. 1979. Practical Ethics. Cambridge: Cambridge University Press.
Singer, P. 1990. Animal Liberation, second edition. London: Jonathan Cape.
Singer, P. 1993. Practical Ethics, second edition. Cambridge: Cambridge University Press.
Singer, P. 2011. Practical Ethics, third edition. Cambridge: Cambridge University Press.
Singh, P., Schimenti, J.C. and Bolcun-Filas, E. 2015. A mouse geneticist’s practical guide to CRISPR applications. Genetics 199: 1–15.
Smith, J.A. and Boyd, K.M. (eds.) 1991. Lives in the Balance: The Ethics of Using Animals in Biomedical Research. Oxford: Oxford University Press.
Smyth, D.H. 1978. Alternatives to Animal Experiments. London: Scolar Press.
Sneddon, L.U., Elwood, R.W., Adamo, S.A. and Leach, M.C. 2014. Defining and assessing animal pain. Animal Behaviour 97: 201–212.
Stephens, M.L. 1986. Maternal Deprivation Experiments in Psychology: A Critique of Animal Models. Jenkinstown, PA: The American Anti-Vivisection Society.
Stephens, M.L. and Mak, N.S. 2014. History of the 3Rs in toxicity testing: from Russell and Burch to 21st century toxicology. In Allen, D.G. and Waters, M.D. (eds.), Reducing, Refining and Replacing the Use of Animals in Toxicity Testing, pp. 1–43. Cambridge: The Royal Society of Chemistry.
Stevens, C. 1990. Laboratory animal welfare. In Leavett, E.S. (ed.), Animals and their Legal Rights, pp. 66–105. Washington DC: Animal Welfare Institute.
Stone, M. 1989. Cited in Animal Experimentation, Australian Government, Senate Select Committee on Animal Welfare. Canberra: Australian Government Publishing Service.
Swami, V., Furnham, A. and Christopher, A.N. 2008. Free the animals? Investigating attitudes toward animal testing in Britain and the United States. Scandinavian Journal of Psychology 49: 269–276.
Tannenbaum, J. and Bennett, B.T. 2015. Russell and Burch’s 3Rs then and now: the need for clarity in definition and purpose. Journal of the American Association for Laboratory Animal Science 54: 120–132.
Taylor, K., Gordon, N., Langley, G. and Higgins, W. 2008. Estimates for worldwide laboratory animal use in 2005. Alternatives to Laboratory Animals 36: 327–342.
Townsend, P. and Morton, D.B. 1995. Laboratory animal care policies and regulations: United Kingdom. ILAR Journal 37: 68–74.
Tsunoda, M., Kido, T., Mogi, S., Sugiura, Y., Miyajima, E., Kudo, Y., Kumazawa, T. and Aizawa, Y. 2014. Skin irritation to glass wool or continuous glass filaments as observed by a patch test among human Japanese volunteers. Industrial Health 52: 439–444.
Turner, J. 1980. Reckoning with the Beast: Animals, Pain and Humanity in the Victorian Mind. Baltimore, MD: Johns Hopkins University Press.
Tyebkhan, G. 2003. Declaration of Helsinki: the ethical cornerstone of human clinical research. Indian Journal of Dermatology, Venereology and Leprology 69: 245–247.
US Congress, Office of Technology Assessment 1986. Alternatives to Animal Use in Research, Testing, and Education. Washington DC: US Government Printing Office.
Use of Fishes in Research Committee 2013. Guidelines for the Use of Fishes in Research. Bethesda, MD: American Fisheries Society.
van der Ploeg, A.T. and Reuser, A.J.J. 2008. Pompe’s disease. Lancet 372: 1342–1353.
Voltaire, , 1764/1962. Philosophical Dictionary, pp. 112–113, trans. Gay, P. New York: Basic Books.
Wade, N. 1978. New vaccine may bring man and chimpanzee into tragic conflict. Science 200: 1027–1030.
Wall, P.D. 1992. Humane treatment of animals does not mean treating animals as humans. In Kuchel, T.R., Rose, M. and Burrell, J. (eds.), Animal Pain: Ethical and Scientific Perspectives, pp. 1–12. Adelaide: ACCART.
Walsh, M. and Richmond, J. 2005. Regulation of animal experimentation in the United Kingdom. School Science Review 87 (319): 85–89.
Waugh, C. and Monamy, V. 2016. Opposing lethal wildlife research when non-lethal methods exist: scientific whaling as a case study. Journal of Fish and Wildlife Management 7: 231–236.
Weiss, J.M. 1972. Psychological factors in stress and disease. Scientific American 226: 104–113.
Wells, D.J., Playle, L.C., Enser, W.E., Flecknell, P.A., Gardiner, M.A., Holland, J., Howard, B.R., Hubrecht, R., Humphreys, K.R., Jackson, I.J., Lane, N., Maconochie, M., Mason, G., Morton, D.B., Raymond, R., Robinson, V., Smith, J.A. and Watt, N. 2006. Assessing the welfare of genetically altered mice. Laboratory Animals 40: 111–114.
White, J.R. 2014. A brief history of the development of diabetes medications. Diabetes Spectrum 27 : 82–86.
Whittaker, A.L. and Howarth, G.S. 2014. Use of spontaneous behaviour measures to assess pain in laboratory rats and mice: how are we progressing? Applied Animal Behaviour Science 151: 1–12.
Wick, P. Chortarea, S., Guenat, O.T., Roesslein, M., Stucki, J.D., Hirn, S., Petri-Fink, A. and Rothen-Rutishauser, B. 2015. In vitro-ex vivo model systems for nanosafety assessment. European Journal of Nanomedicine 7: 169–179.
Wickens, S.M. 2007. Science in the Service of Animal Welfare: A Chronicle of Eighty Years of Service. London: UFAW.
Wise, S.M. 2000. Rattling the Cage: Towards Legal Rights for Animals. Cambridge, MA: Perseus Books.
Wise, S.M. 2002. Drawing the Line: Science and the Case for Animal Rights. Cambridge, MA: Perseus Books.
Wolfensohn, S. and Lloyd, M. 2013. Handbook of Laboratory Animal Management and Welfare, fourth edition. Oxford: Wiley-Blackwell.
Wong, J. 1995. Laboratory animal care policies and regulations: Canada. ILAR Journal 37: 57–59.
Yum, S., Woo, S., Lee, A., Won, H. and Kim, J. 2014. Hydra, a candidate for an alternative model in environmental genomics. Molecular and Cellular Toxicology 10: 339–346.
Zhang, J., Hsieh, J. and Zhu, H. 2014. Profiling animal toxicants by automatically mining public bioassay data: a big data approach for computational toxicology. PloS One 9(6): e99863. doi: 10.1371/journal.pone.0099863.
Zheng, F., Fu, F., Cheng, Y., Wang, C., Zhao, Y. and Gu, Z. 2016. Organ-on-a-chip systems: microengineering to biomimic living systems. Small 12: 2253–2282.
Zhu, H., Kim, M., Zhang, L. and Sedykh, A. 2014. Computers instead of cells: computational modelling of chemical toxicity. In Allen, D.G. and Waters, M.D. (eds.), Reducing, Refining and Replacing the Use of Animals in Toxicity Testing, pp. 163–182. Cambridge: The Royal Society of Chemistry.