Book contents
- Perinatal Neuropathology
- Perinatal Neuropathology
- Copyright page
- Contents
- Preface
- Acknowledgments
- Abbreviations
- Section I Techniques and Practical Considerations
- Section 2 Human Nervous System Development
- Neuroanatomic Site Development
- Chapter 19 Human Nervous System Development: Embryonic and Early Fetal Events
- Chapter 20 Cerebral Cortex, Including Germinal Matrix
- Chapter 21 White Matter, Including Myelination
- Chapter 22 Cerebellum: Development of the Rhombic Lip, Cerebellar Cortex, Dentate Nucleus
- Chapter 23 Spinal Cord
- Chapter 24 Skeletal Muscle and Peripheral Nerve
- Chapter 25 Fetal and Infant Eye
- Growth Parameters
- Section 3 Stillbirth
- Section 4 Disruptions / Hypoxic-Ischemic Injury
- Section 5 Malformations
- Section 6 Perinatal Neurooncology
- Section 7 Spinal and Neuromuscular Disorders
- Section 8 Eye Disorders
- Section 9 Infections: In Utero Infections
- Section 10 Metabolic / Toxic Disorders: Storage Diseases
- Section 11 Forensic Neuropathology
- Appendix 1 Technical Considerations in Perinatal CNS
- Index
- References
Chapter 20 - Cerebral Cortex, Including Germinal Matrix
from Neuroanatomic Site Development
Published online by Cambridge University Press: 07 August 2021
Book contents
- Perinatal Neuropathology
- Perinatal Neuropathology
- Copyright page
- Contents
- Preface
- Acknowledgments
- Abbreviations
- Section I Techniques and Practical Considerations
- Section 2 Human Nervous System Development
- Neuroanatomic Site Development
- Chapter 19 Human Nervous System Development: Embryonic and Early Fetal Events
- Chapter 20 Cerebral Cortex, Including Germinal Matrix
- Chapter 21 White Matter, Including Myelination
- Chapter 22 Cerebellum: Development of the Rhombic Lip, Cerebellar Cortex, Dentate Nucleus
- Chapter 23 Spinal Cord
- Chapter 24 Skeletal Muscle and Peripheral Nerve
- Chapter 25 Fetal and Infant Eye
- Growth Parameters
- Section 3 Stillbirth
- Section 4 Disruptions / Hypoxic-Ischemic Injury
- Section 5 Malformations
- Section 6 Perinatal Neurooncology
- Section 7 Spinal and Neuromuscular Disorders
- Section 8 Eye Disorders
- Section 9 Infections: In Utero Infections
- Section 10 Metabolic / Toxic Disorders: Storage Diseases
- Section 11 Forensic Neuropathology
- Appendix 1 Technical Considerations in Perinatal CNS
- Index
- References
Summary
Basic organization of the CNS is established during the embryonic and early fetal period (see Chapter 19). However, at this stage, the human brain is barely formed. From the 20th to the 40th week of gestation, brain weight increases tenfold. It doubles again during the first year of postnatal life, and continues to increase another 50% during the next 10 to 15 years when adult weight is finally reached (see Chapter 26) (1). Growth is accomplished through several processes. The quantity of brain cells increases at a brisk rate in the periventricular germinal matrix until approximately 30 weeks gestation and at a much lesser rate until approximately full-term gestation (2).
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- Chapter
- Information
- Perinatal Neuropathology , pp. 88 - 100Publisher: Cambridge University PressPrint publication year: 2021
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