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Chapter 30 - The Physiology of Blood and Its Administration

Published online by Cambridge University Press:  18 August 2022

By
Suzanne Arulogun  and
Paul Wheeler
Edited by
Daniel Rodger ,
Kevin Henshaw ,
Paul Rawling  and
Scott Miller
Daniel Rodger
Affiliation:
Senior Lecturer in Perioperative Practice, London South Bank University
Kevin Henshaw
Affiliation:
Associate Head of Allied Health Professions, Edge Hill University, Ormskirk
Paul Rawling
Affiliation:
Senior Lecturer in Perioperative Practice, Edge Hill University, Ormskirk
Scott Miller
Affiliation:
Consultant Anaesthetist, St Helens and Knowsley Hospitals NHS Trust
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Summary

An understanding of the physiological role of blood and its role in the supply of oxygen to tissues is important for the perioperative care of the patient. A thorough approach to administration of blood components is vital in this setting. This chapter adresses the special properties of the red blood cells in promoting oxygen carriage, the methods of safe blood component transfusion, and consideration of the hazards of transfusion.

Keywords

Blood transfusionTransfusion reactionsBlood groupingBlood donationOxygen affinity
Type
Chapter
Information
Fundamentals of Operating Department Practice , pp. 334 - 346
Publisher: Cambridge University Press
Print publication year: 2022

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References

Qureshi, H., Massey, E., Kirwan, D., et al. BCSH guideline for the use of anti-D immunoglobulin for the prevention of haemolytic disease of the fetus and newborn. Transfusion Medicine 2014; 24: 8–20.CrossRefGoogle ScholarPubMed
Norfolk, D.. Transfusion handbook, 5th edition: Joint United Kingdom (UK) Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee. Available from www.transfusionguidelines.org/transfusion-handbook/publication-information.pdf.Google Scholar
Narayan, S. (ed.), M. Bellamy, D. Poles, et al., on behalf of the Serious Hazards of Transfusion (SHOT) steering group. The annual SHOT report 2019. Available from: www.shotuk.org/wp-content/uploads/myimages/SHOT-REPORT-2019-Final-Bookmarked-v2.pdf.Google Scholar
Joint United Kingdom (UK) Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee. Guidelines for the Blood Transfusion Services in the United Kingdom (the Red Book). Available from: www.transfusionguidelines.org.uk.Google Scholar
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Green, L., Bolton-Maggs, P., Beattie, C., et al. British Society of Haematology guidelines on the spectrum of fresh frozen plasma and cryoprecipitate products: their handling and use in various patient groups in the absence of major bleeding. British Journal of Haematology 2018; 181: 54–67.Google Scholar
PID UK. Selective IgA deficiency patient information sheet. Available from: https://mft.nhs.uk/app/uploads/sites/7/2018/04/SelectiveIgAdeficiencypatientsheet.pdf.Google Scholar
Hunt, B. J., Allard, S., Keeling, D., et al. A practical guideline for the haematological management of major haemorrhage. British Journal of Haematology 2015; 170: 788–803.CrossRefGoogle ScholarPubMed

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