We present epistemic multilateral logic, a general logical framework for reasoning involving epistemic modality. Standard bilateral systems use propositional formulae marked with signs for assertion and rejection. Epistemic multilateral logic extends standard bilateral systems with a sign for the speech act of weak assertion (Incurvati & Schlöder, 2019) and an operator for epistemic modality. We prove that epistemic multilateral logic is sound and complete with respect to the modal logic $\mathbf {S5}$ modulo an appropriate translation. The logical framework developed provides the basis for a novel, proof-theoretic approach to the study of epistemic modality. To demonstrate the fruitfulness of the approach, we show how the framework allows us to reconcile classical logic with the contradictoriness of so-called Yalcin sentences and to distinguish between various inference patterns on the basis of the epistemic properties they preserve.

This study examined differences in friendship quality between children with traumatic brain injury (TBI) and orthopedic injury (OI) and behavioral outcomes for children from both groups. Participants were 41 children with TBI and 43 children with OI (M age=10.4). Data were collected using peer- and teacher-reported measures of participants’ social adjustment and parent-reported measures of children’s post-injury behaviors. Participants and their mutually nominated best friends also completed a measure of the quality of their friendships. Children with TBI reported significantly more support and satisfaction in their friendships than children with OI. Children with TBI and their mutual best friend were more similar in their reports of friendship quality compared to children with OI and their mutual best friends. Additionally, for children with TBI who were rejected by peers, friendship support buffered against maladaptive psychosocial outcomes, and predicted skills related to social competence. Friendship satisfaction was related to higher teacher ratings of social skills for the TBI group only. Positive and supportive friendships play an important role for children with TBI, especially for those not accepted by peers. Such friendships may protect children with TBI who are rejected against maladaptive psychosocial outcomes, and promote skills related to social competence. (JINS, 2014, 21, 1–10)

When mice were treated with 1–25 mg cortisone acetate thrice weekly, recovery of Hymenolepis murissylvaticae was significantly higher than in untreated controls, both in oral infections with six cysticercoids and surgical transplantations of one 7-day or 8-day-old worm. Cortisone treatment also resulted in the worms being located more anteriorly in the small intestine. Evidence of an immunological response against the tapeworm in the intestine is given by: (a) an accelerated rejection of a secondary oral cysticercoid infection and a significant difference of the dry weights of the worms recovered on day 10 in CFLP mice; (b) an accelerated rejection of a secondary surgical infection on days 4 and 6 in CFLP mice and on days 3 and 4 in NMRI mice; (c) an accelerated rejection of a secondary surgical infection given 3 and 6 months after the primary immunizing infection in SWlSS-albino mice.

Year 12 students are in a transitional year, academically and interpersonally. This year involves many changes and the need for students to make future plans, which can be a challenge for many adolescents. During times of transition, such as Year 12, expectations and beliefs about relationships and the relational self (i.e., attachment patterns) may undergo changes. Identifying attachment patterns among Australian Year 12 students was the first aim of this 6-month longitudinal study (N = 130, M age = 16.4). A second aim of this study was to determine correlates of attachment change and stability. These correlates included psychological symptoms, loneliness, rejection sensitivity, social competence, and social support. Using an adolescent version of Bartholomew and Horowitz’s (1991) Relationship Questionnaire, self-reported attachment style showed some change, with 36% of adolescents changing attachment style category during the study. Adolescents were classified into groups based on their attachment styles at the two assessments. Groups included adolescents who were stably insecure, stably insecure, changed to insecure and changed to insecure. When groups were compared, most hypothesised differences were found. First, stably insecure individuals had the most positive psychological functioning, and they had the most stable and positive perceptions of self and others when compared to other groups. Second, stably insecure adolescents were less well-adjusted than others. Third, the changed to insecure group showed improvements in functioning over time. However, it was not clear that adjustment had declined in the changed to insecure group.

The spring of 2005 saw major set-backs for the Treaty of Rome of 29 October 2004, establishing what it calls ‘a Constitution for Europe’. On 29 May, the French rejected the Treaty in their referendum by 54,8% (turnout 70%). Then the Dutch rejected it on 1 June by an even more massive 61,7% (turnout 63%). In response to these refusals the member states agreed to a ‘reflection period’ and a suspension of the ratification deadline at the European Council of 16 and 17 June. In the subsequent 10 July Luxembourg referendum 56,2% of the electorate voted in favour (obligatory vote), a significant drop from polls in October 2004, but at least creating a simple majority of 13 member states to ratify the document. But the UK put its ratification on hold, followed by other countries.

Origin of referendum discussion in the Convention. The national debate on referenda. The crucial role of the liberal party. Referendum bill private members initiative. Referendum Act an ad hoc consultative referendum. Referendum the first opportunity for a broad political debate on the EU. Complacency and disorganised arguments of the ‘yes’ campaign. First analyses of referendum.

On 21 September 1792, at Danton's proposal, the French National Assembly declared that ‘there can be no constitution but one approved by the people’. In France, the idea of direct democracy dates back to the Revolution. However, due to the Terror and the practice under Napoleonic Empires, in which they were turned into plebiscites, referendums acquired a negative connotation. Under the Vth Republic, De Gaulle turned referendums into an instrument of personalisation and presidentialisation, and since his day, there have been few referendums staged. In 10 years of office, President Jacques Chirac only used it twice with much less success and political courage.

Gene therapy continues to offer much hope for the future treatment of a variety of clinical conditions. The development of tailored, novel gene transfer vectors will improve the efficiency and stability of therapeutic gene expression in the many settings of gene therapy. In the context of tissue and organ transplantation, gene therapy is being harnessed to prevent the acute and chronic rejection of transplanted tissues by introducing either new genes that are important in preventing rejection (e.g. co-stimulatory blocking molecules or immunosuppressive cytokines) or antisense nucleic acids to block the production of rejection-associated molecules such as adhesion molecules. The delivery of genes by gene therapy vectors that encode foreign donor antigens (alloantigens) might also be an effective means of inducing donor-specific unresponsiveness (immunological tolerance) in the recipient, perhaps eliminating the requirement for potentially harmful whole-body immunosuppression.