Fifty to eighty-five percent of schizophrenic patients are impaired on ocular pursuit paradigms. However, results regarding the relatives are more discordant. The aim of this study was to investigate whether eye movement disorders could be a vulnerability marker of schizophrenia.

Recently, we showed that contrast sensitivity for color and high–spatial frequency luminance stimuli is enhanced during smooth pursuit eye movements (Schütz et al., 2008). In this study, we investigated the enhancement over a wide range of temporal and spatial frequencies. In Experiment 1, we measured the temporal impulse response function (TIRF) for colored stimuli. The TIRF for pursuit and fixation differed mostly with respect to the gain but not with respect to the natural temporal frequency. Hence, the sensitivity enhancement seems to be rather independent of the temporal frequency of the stimuli. In Experiment 2, we measured the spatial contrast sensitivity function for luminance-defined Gabor patches with spatial frequencies ranging from 0.2 to 7 cpd. We found a sensitivity improvement during pursuit for spatial frequencies above 2–3 cpd. Between 0.5 and 3 cpd, sensitivity was impaired by smooth pursuit eye movements, but no consistent difference was observed below 0.5 cpd. The results of both experiments are consistent with an increased contrast gain of the parvocellular retinogeniculate pathway.

The effect of attention allocation on smooth pursuit eye movements (SPEM) was investigated. Eye movements were electrooculographically recorded in 27 healthy subjects who tracked a visual target that moved horizontally with constant or unpredictably varying velocity. In some trials, subjects performed additional auditory discrimination tasks varying in difficulty. Pursuit error decreased when attention was divided between both tasks. The pattern of results is incompatible with the assumption made in previous research that attention enhancement improves SPEM accuracy. Rather, ocular smooth pursuit appears to be executed in the automatic mode, although intentional and selective processes must contribute. Moreover, controlled attention directed to the tracking task interfered with smooth pursuit. A reinterpretation of earlier studies in which visual monitoring tasks were used to improve eye tracking is needed.