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A variety of testing modalities are available in the emergency department (ED) to enable diagnosis of headache. For an emergency care provider, the goal is to order those tests that will facilitate diagnosis in a timely manner, without burdening the patient and healthcare system with unnecessary tests, particularly those tests that are time-consuming, uncomfortable, or expensive. Available diagnostic tests include analyses of blood, urine, and cerebrospinal fluid (CSF), as well as a variety of neuroimaging modalities. In this chapter, we discuss the utility, indication, and best practice with regard to the many tests commonly available in an ED.
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