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Several airborne radar-sounding surveys are used to trace internal reflections around the European Project for Ice Coring in Antarctica Dome C and Vostok ice core sites. Thirteen reflections, spanning the last two glacial cycles, are traced within 200 km of Dome C, a promising region for million-year-old ice, using the University of Texas Institute for Geophysics High-Capacity Radar Sounder. This provides a dated stratigraphy to 2318 m depth at Dome C. Reflection age uncertainties are calculated from the radar range precision and signal-to-noise ratio of the internal reflections. The radar stratigraphy matches well with the Multichannel Coherent Radar Depth Sounder (MCoRDS) radar stratigraphy obtained independently. We show that radar sounding enables the extension of ice core ages through the ice sheet with an additional radar-related age uncertainty of ~1/3–1/2 that of the ice cores. Reflections are extended along the Byrd-Totten Glacier divide, using University of Texas/Technical University of Denmark and MCoRDS surveys. However, core-to-core connection is impeded by pervasive aeolian terranes, and Lake Vostok's influence on reflection geometry. Poor radar connection of the two ice cores is attributed to these effects and suboptimal survey design in affected areas. We demonstrate that, while ice sheet internal radar reflections are generally isochronal and can be mapped over large distances, careful survey planning is necessary to extend ice core chronologies to distant regions of the East Antarctic ice sheet.
Age-related hearing impairment (ARHI) is a common condition with complex etiology but a recognized genetic component. Heritability estimates for pure tone audiogram-determined hearing ability lie in the range 26–75%. The speech-in-noise (SIN) auditory test, however, may be better at encapsulating ARHI symptoms, particularly the diminished ability to segregate environmental sounds into comprehendible auditory streams. As heritability of SIN has not previously been reported, we explored the genetic and environmental contributions to ARHI determined by SIN in 2,076 twins (87.8% female) aged 18–87 (mean age 54.4). SIN was found to be significantly heritable (A, unadjusted for age = 40%; 95% confidence intervals, CI = 32%–47%). With age adjustment, heritability fell (A = 25%; 95% CI = 16–33%), and a relatively strong influence of environmental exposure unshared within twin siblings was identified (E = 75%). To explore the environmental aspects further, we assessed the influence of diet (through the Food Frequency Questionnaire, FFQ), smoking (through self-report and cotinine metabolite levels) and alcohol intake (through the FFQ). A negative influence of high cholesterol diet was observed after adjustment (p = .037). A protective effect of raised serum high-density lipoprotein (HDL) cholesterol levels was observed after adjustment (p = .004). This study is the first assessment of the genetic and environmental influence on SIN perception. The findings suggest SIN is less heritable than pure tone audiogram (PTA) ability and highly influenced by the environment unique to each twin. Furthermore, a possible role of dietary fat in the etiology of ARHI is highlighted.
Introduction
The fertility nurse is an essential member of a multi-professional team whose focus is to ensure the delivery of quality care to patients. Information regarding ovulation induction (OI) and intrauterine insemination (IUI) is introduced to the patient by multiple team members, but most importantly by the nurse. The nurse works with the physicians and other team members, and becomes the primary advocate for the patient.
After the physician designs a plan of treatment based on his or her initial assessment and diagnosis, it is the nurse who coordinates and implements the plan of treatment. During the planning phase, the nurse becomes the primary caregiver and has the majority of interaction with the patient. The nurse's role is to direct couples through their treatment by explaining and defining all procedures and instructions clearly and concisely. It is very important for the nurse to be knowledgeable, compassionate, confident and empathetic.
The nurse implements the physician's plan of treatment by formulating and reviewing the OI patient's cycle calendar, ordering and instructing on the administration of oral or injectable medications, and educating on potential risks and/or side effects. The nurse teaches the patient the purpose of each step in the treatment protocol. The nurse reviews results of ultrasound and labs, and then communicates these results with the physician so as to instruct the patient with her plan of treatment. The nurse has an important role in teaching the patient regarding ovulation predictor kits.
Occasionally the nurse's role includes discussion of costs involved.
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