A new optical delivery system has been developed for the (scanning) transmission electron microscope. Here we describe the in situ and “rapid ex situ” photothermal heating modality of the system, which delivers >200 mW of optical power from a fiber-coupled laser diode to a 3.7 μm radius spot on the sample. Selected thermal pathways can be accessed via judicious choices of the laser power, pulse width, number of pulses, and radial position. The long optical working distance mitigates any charging artifacts and tremendous thermal stability is observed in both pulsed and continuous wave conditions, notably, no drift correction is applied in any experiment. To demonstrate the optical delivery system’s capability, we explore the recrystallization, grain growth, phase separation, and solid state dewetting of a Ag0.5Ni0.5 film. Finally, we demonstrate that the structural and chemical aspects of the resulting dewetted films was assessed.

This paper explores how the Generalized Continuum Hypothesis (GCH) arose from Cantor's Continuum Hypothesis in the work of Peirce, Jourdain, Hausdorff, Tarski, and how GCH was used up to Gödel's relative consistency result.

The Val158Met polymorphism of the catechol-O-methyltransferase (COMT) gene may be related to individual differences in cognition, likely via modulation of prefrontal dopamine catabolism. However, the available studies have yielded mixed results, possibly in part because they do not consistently account for other genes that affect cognition. We hypothesized that COMT Met allele homozygosity, which is associated with higher levels of prefrontal dopamine, would predict better executive function as measured using standard neuropsychological testing, and that other candidate genes might interact with COMT to modulate this effect. Participants were 95 healthy, right-handed adults who underwent genotyping and cognitive testing. COMT genotype predicted executive ability as measured by the Trail-Making Test, even after covarying for demographics and Apolipoprotein E (APOE), brain-derived neurotrophic factor (BDNF), and ankyrin repeat and kinase domain containing 1 (ANKK1) genotype. There was a COMT-ANKK1 interaction in which individuals having both the COMT Val allele and the ANKK1 T allele showed the poorest performance. This study suggests the heterogeneity in COMT effects reported in the literature may be due in part to gene–gene interactions that influence central dopaminergic systems. (JINS, 2011, 17, 1–7)

Each year, more and more of Canada's vast northern territories are being explored in the search for untapped mineral resources. But the area is covered with snow for seven to ten months a year, which hampers most activities connected with mineral exploration. Snow cover also affects changes in albedo and temperature and hydrologic forecasting. The surface hydrology in most areas is only active for two to five months a year. Historically, snow hydrologists have been limited to the use of ground source measurements for estimating the spatial and temporal variability of snow cover. In the Yukon and Northwest Territories hydrometeorological stations are few and tend to be clustered around settlements. Moreover, the ground source data are subject to error and do not necessarily provide a complete picture of current conditions. The synoptic view provided by satellite images presents an economical way to monitor the retreat and advance of the snow-line and of mapping snow cover in remote and sparsely populated areas. The information may eventually be useful for extrapolating conventional ground source data more effectively over the entire Yukon and Northwest Territories.