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1 results

  • Hippocampal volume and 2-year outcome indepression

  • Klaus-Thomas Kronmüller, Johannes Pantel, Sebastian Köhler, Daniela Victor, Frederik Giesel, Vincent A. Magnotta, Christoph Mundt, Marco Essig, Johannes Schröder
  • Journal:
    The British Journal of Psychiatry / Volume 192 / Issue 6 / June 2008
    Published online by Cambridge University Press:
    02 January 2018, pp. 472-473
    Print publication:
    June 2008
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  • Although the hippocampus has been found to be smaller in people withdepression, the clinical relevance of this is unclear. We investigatedhippocampal volume (using high-resolution magnetic resonance imaging) and2-year outcome in 57 patients with major depression. The left and righthippocampal volumes of patients with a depression relapse were significantlysmaller than those of healthy controls. Our results support the hypothesisthat the hippocampus is crucial in the outcome of depression.