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1 results

  • Commentary: Genetic modification through oligonucleotide-mediated mutagenesis. A GMO regulatory challenge?

  • Didier Breyer, Philippe Herman, Annick Brandenburger, Godelieve Gheysen, Erik Remaut, Patrice Soumillion, Jan Van Doorsselaere, René Custers, Katia Pauwels, Myriam Sneyers, Dirk Reheul
  • Journal:
    Environmental Biosafety Research / Volume 8 / Issue 2 / April 2009
    Published online by Cambridge University Press:
    10 July 2009, pp. 57-64
    Print publication:
    April 2009
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  • In the European Union, the definition of a GMO is technology-based. This means that a novel organism will be regulated under the GMO regulatory framework only if it has been developed with the use of defined techniques. This approach is now challenged with the emergence of new techniques. In this paper, we describe regulatory and safety issues associated with the use of oligonucleotide-mediated mutagenesis to develop novel organisms. We present scientific arguments for not having organisms developed through this technique fall within the scope of the EU regulation on GMOs. We conclude that any political decision on this issue should be taken on the basis of a broad reflection at EU level, while avoiding discrepancies at international level.