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Shiga toxin-producing Escherichia coli (STEC) is a group of bacteria that causes gastrointestinal illness and occasionally causes large foodborne outbreaks. It represents a major public health concern due to its ability to cause severe illness which can sometimes be fatal. This study was undertaken as part of a rapid investigation into a national foodborne outbreak of STEC O145. On 22 May 2024, United Kingdom (UK) public health agencies and laboratories identified an increase in stool specimens submissions and patients testing positive for Shiga toxin-producing E. coli (STEC). Whole genome sequencing (WGS) identified serotype O145:H28 stx2a/eae belonging to the same five single nucleotide polymorphism (SNP) single linkage cluster as the causative agent. By 3 July 2024, 288 cases had been linked to the cluster. Most cases were adults (87%) and females (57%), 49% were hospitalized with a further 10% attending emergency care. Descriptive epidemiology and analytical studies were conducted which identified consumption of nationally distributed pre-packed sandwiches as a common food exposure. The implicated food business operators voluntarily recalled ready-to-eat sandwiches and wraps containing lettuce on 14 June 2024.
Even amidst a decline in religious affiliation, nearly half of the U.S. population still attends religious services at least once a month, and congregations remain the single largest non-profit organizational type across the nation. Therefore, congregational influence on political attitudes and behavior is a crucial line of inquiry. We analyze interviews of 94 congregational leaders to better understand why they address or avoid political issues when preaching. Our research reveals that clergy use theological and pragmatic reasoning to determine whether they explicitly include political discourse in their sermons. Our findings are noteworthy in that clergy from a wide range of religious traditions use similar reasoning, and the same rationale can lead different clergy to adopt contrasting approaches to political content in sermons. Thus, this paper provides nuanced insight into the relationship between religion and politics and may help foster greater mutual understanding in a deeply divided political and social climate.
Looting and plough damage to the eighth–fifth centuries BC tumulus of Creney-le-Paradis, France, hinders interpretation of this potentially significant site. Nevertheless, application of novel microtomographic techniques in combination with optical and scanning electron microscopy allows the first detailed examination of 99 textile fragments recovered from the central pit. The authors argue that the diversity of textiles revealed—at least 16 different items—and the quality of weaving involved confirm earlier interpretations of the high status of this burial, which is comparable, at least in terms of textiles and metal urns, with other ‘aristocratic’ tombs of the European Iron Age.
This chapter, derived mainly from business-to-business serials such as The Bookseller[GK7], represents publishing in the 1860s as a collaborative enterprise comprising several interlocking systems. Basing its viewpoint in business-to-business texts shows that, unlike what is often suggested, it was not revolutionary. Instead, its use of technology and its distribution systems underwent a process of mainstreaming that intensified and refined extant methods of advertising, marketing, transport, wholesale, retail, and lending. Regulation was different, not because the various changes in the law offered anything new, but because details were modified in an attempt to improve them. Unlike many studies of publishing, this one engages with the regulation of labor relations, international distribution, and changing forms of business ownership as well as of the contents and ownership of texts through the laws of copyright, obscenity, and libel.
This study aimed to assess degree of audiovestibular handicap in patients with vestibular schwannoma.
Methods
Audiovestibular handicap was assessed using the Hearing Handicap Inventory, Tinnitus Handicap Inventory and Dizziness Handicap Inventory. Patients completed questionnaires at presentation and at least one year following treatment with microsurgery, stereotactic radiosurgery or observation. Changes in audiovestibular handicap and factors affecting audiovestibular handicap were assessed.
Results
All handicap scores increased at follow up, but not significantly. The Tinnitus Handicap Inventory and Dizziness Handicap Inventory scores predicted tinnitus and dizziness respectively. The Hearing Handicap Inventory was not predictive of hearing loss. Age predicted Tinnitus Handicap Inventory score and microsurgery was associated with a deterioration in Dizziness Handicap Inventory score.
Conclusion
Audiovestibular handicap is common in patients with vestibular schwannoma, with 75 per cent having some degree of handicap in at least one inventory. The overall burden of handicap was, however, low. The increased audiovestibular handicap over time was not statistically significant, irrespective of treatment modality.