Breeding schemes with multiple ovulation and embryo transfer opens up a possibility to enhance genetic improvement through intense female selection and short generation intervals. The potential improvement in genetic response may increase when elite cows produce a number of embryos, instead of one calf per year. Also different ratio of proven bull and young bull semen may be used to inseminate cows in the herd. The objective of this project has been to investigate genetic response and coefficient of inbreeding, when elite cows produce number of embryos during a year, instead of reproducing one calf per year. Also genetic response and inbreeding coefficient were estimated when different ratio of proven bull and young bull semen were used to inseminate cows in the herd.