Schizophrenic patients are referred to frequently as immunologically incompetent or poor antibody responders. However, if the literature comparing the response of immunized chronic schizophrenics with non-schizophrenic controls is examined, contradictory results may be found (1). Development of allergic responsiveness in schizophrenics as compared to control subjects was also studied with controversial results (4, 2). No studies have been reported in which the antibody response of schizophrenic patients was measured quantitatively simultaneously with the development of an allergic skin reaction following sensitization.