Disarmament and non-proliferation education is a key tool in curbing the spread of nuclear weapons, with a view to their elimination. This article examines the remarkable story of the International School on Disarmament and Research on Conflicts (ISODARCO) on the occasion of its fiftieth anniversary of continuous engagement in educational and training activities. ISODARCO offers a unique forum where nuclear experts from different backgrounds and approaches can meet, debate, and promote action as a transnational knowledge-based network of experts and, equally important, pass on their expertise to the ‘next generation of non-proliferation specialists’. The contribution of this small Italian NGO is indeed noteworthy, highly praised at the national and especially international level, and worth the attention of an audience broader than just non-proliferation and security experts.