Space matters for global politics but the treatment thereof in International Relations (IR) has been uneven. There is broad interest in spatial aspects across many research communities but only a nascent theoretical discussion and little cross-field communication. This article argues for a fuller engagement of IR scholars with sociospatial concepts and proposes a spatial approach to global politics based on four essential dimensions: a spatial ontology, the constructedness of space, a scalar perspective, and the interaction of materiality and ideas. As one possible way of integrating these aspects into a more specific concept, the article elaborates a framework of spatial practices and uses the example of Arctic Security research to illustrate the upsides of such a spatial approach for IR research.